Devices, systems and methods for actuation and retraction in fluid collection

• US 10,426,390 B2
• Filed: 12/21/2016
• Issued: 10/01/2019
• Est. Priority Date: 12/21/2015
• Status: Active Grant

• Current Assignee: Tasso, Inc.
• Original Assignee: Tasso, Inc.
• Inventors: Berthier, Erwin, Casavant, Ben, Moga, Ben
• Primary Examiner(s): McCrosky, David J.
• Application Number:
  US15/387,177
• Publication Number:
  US 20170172481A1
• Time in Patent Office: 1,014 Days
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150167 Adjustable piercing speed of skin piercing element, e.g. blade, needle, lancet or canula, for example with varying spring force or pneumatic drive
• CPC Class Codes: A61B 5/150175 Adjustment of penetration depth
• CPC Class Codes: A61B 5/150221 Valves
• CPC Class Codes: A61B 5/150236 Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150908 by disconnecting components, e.g. breaking or rupturing of connected parts, e.g. piston and rod
• CPC Class Codes: A61B 5/150916 by blocking components, e.g. piston, driving device or fluid passageway
• CPC Class Codes: A61B 5/150984 Microneedles or microblades
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15115 Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/15144 comprising driving means, e.g. a spring, for retracting the piercing unit into the housing

Abstract

The disclosed apparatus, systems and methods relate to devices, systems and methods for the collection of bodily fluids involving a single-use actuation and retraction mechanism disposed within a collector.

Claims

1. A collector for collecting fluid from a subject, the collector comprising:

a housing having a base and an elongate guide, wherein the housing defines a lumen, and wherein a distal surface of the base is configured to be positioned against a skin surface of the subject;

an actuator positioned at least partially within the lumen and having an actuator arm, wherein a distal portion of the elongate guide and a distal portion of the actuator arm together define a locking feature, and wherein the actuator is configured to be moved through the lumen toward the base;

a platform positioned at least partially within the lumen between the actuator and the base, wherein the platform includes a platform projection configured to engage the locking feature;

and

a plunger operably coupled to the platform and having a lancet,

wherein the actuator is movable from (a) a first position relative to the base in which the lancet extends past the distal surface of the base and (b) a second position nearer to the base than the first position in which the lancet is withdrawn into the lumen of the housing, and

wherein movement of the actuator from the first position to the second position moves the platform projection out of engagement with the locking feature to permit the platform to move through the lumen relative to the actuator in a direction away from the base.

2. The collector of claim 1, further comprising a membrane disposed within the lumen, wherein the membrane is configured to create a fluidic seal within the lumen.

3. The collector of claim 2, wherein the membrane comprises a membrane lumen and a one way valve configured to create a vacuum within the membrane lumen.

4. The collector of claim 2, wherein the membrane comprises a bellows.

5. The collector of claim 1 wherein the distal portion of the actuator arm includes a distal face and a catch face extending from the distal face at a non-zero angle relative to the distal face.

6. The collector of claim 5 wherein the platform projection engages the catch face in the first position.

7. The collector of claim 5 wherein the platform projection is configured to move along the distal face when the actuator is moved toward the base, and wherein the catch face is configured to delay the platform projection from moving out of engagement with the locking feature to increase the total time the lancet extends past the distal surface of the base.

8. The collector of claim 1 wherein movement of the actuator toward the base rotates the platform relative to the base.

9. The collector of claim 1 wherein the actuator engages the platform when the actuator is in the first position, and wherein the actuator does not engage the platform when the actuator is in the second position.

10. The collector of claim 1, further comprising a spring operably coupling the platform to the base, wherein the spring is configured to drive the platform in the direction away from the base when the actuator is moved to the second position and the platform projection disengages the locking feature.

11. The collector of claim 1 wherein the elongate guide is positioned further toward the interior of the lumen than the actuator arm.