Stent with anti-migration feature

• US 10,426,641 B2
• Filed: 07/11/2016
• Issued: 10/01/2019
• Est. Priority Date: 01/17/2008
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Inventors: Clerc, Claude O., Tupil, Sri
• Primary Examiner(s): Mathew, Seema
• Application Number:
  US15/206,577
• Publication Number:
  US 20160317330A1
• Time in Patent Office: 1,177 Days
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/30322 differing in surface structures
• CPC Class Codes: A61F 2002/8486 provided on at least one of the ends
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2250/0026 differing in surface structures
• CPC Class Codes: A61F 2250/0037 differing in height or in length
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/125 having a macromolecular matrix
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials

Abstract

An intraluminal prosthesis includes an outer three-dimensional (3D) anti-migration structure that is attached to the outer wall of a fully covered or partially covered stent to prevent migration and still allow stent removal at a later period of time. A method of manufacturing the intraluminal prosthesis includes attaching the anti-migration structure by usage of a polymer such as polyurethane.

Claims

1. An intraluminal prosthesis comprising:

a radially expandable tubular stent structure having a circumference and a length defining a longitudinal axis, the expandable tubular stent structure having an interior surface, an exterior surface, and a plurality of openings extending through the tubular stent structure from the interior surface to the exterior surface, and wherein the tubular stent structure includes first and second flared end regions and a body region therebetween; and

a polymeric covering surrounding the tubular stent structure and covering the plurality of openings, the polymeric covering having a first end, a second end and a length measured from the first end to the second end along the longitudinal axis;

wherein the polymeric covering includes a plurality of projections extending radially outward from an outer surface of the polymeric covering, wherein an inner surface of the polymeric covering opposite each projection is devoid of projections or recesses along the entire length of the polymeric covering, wherein the plurality of projections include a plurality of polymeric annular rings integrally formed with the polymeric covering, wherein each annular ring extends continuously around the entire circumference of the expandable tubular stent structure, the plurality of projections configured to contact an inner surface of a body lumen to prevent migration of the prosthesis in the body lumen.

2. The intraluminal prosthesis of claim 1, wherein the plurality of projections further includes a plurality of beads spaced apart circumferentially around the tubular stent structure.

3. The intraluminal prosthesis of claim 1, further comprising an adhesive layer disposed between the polymeric covering and the exterior surface of the tubular stent structure to attach the polymeric covering to the expandable tubular stent structure.

4. The intraluminal prosthesis of claim 3, wherein the polymeric covering is non-continuously attached to the tubular stent structure with the adhesive layer at discrete areas.

5. The intraluminal prosthesis of claim 3, wherein the polymeric covering is continuously attached to the tubular stent structure with the adhesive layer throughout the entire length of the tubular stent structure.

6. The intraluminal prosthesis of claim 3, wherein the polymeric covering is a preformed covering attached to the tubular stent structure with the adhesive layer subsequent to formation of the polymeric covering.

7. An intraluminal prosthesis comprising:

a radially expandable tubular stent structure having a length defining a longitudinal axis, the expandable tubular stent structure having an interior surface, an exterior surface, and a plurality of openings extending through the tubular stent structure from the interior surface to the exterior surface, wherein the tubular stent structure includes a first flared end region and a body region; and

a polymeric covering surrounding the tubular stent structure and covering the plurality of openings, the polymeric covering having a first end, a second end and a length measured from the first end to the second end along the longitudinal axis;

wherein the polymeric covering includes a plurality of projections extending radially outward from an outer surface of the polymeric covering, wherein an inner surface of the polymeric covering opposite each projection is devoid of projections or recesses along the entire length of the polymeric covering, wherein the plurality of projections include a plurality of polymeric annular rings integrally formed with the polymeric covering, the plurality of projections configured to contact an inner surface of a body lumen to prevent migration of the prosthesis in the body lumen.

8. The intraluminal prosthesis of claim 7, wherein the plurality of projections are arranged circumferentially around the first flared end region.

9. The intraluminal prosthesis of claim 7, further comprising an adhesive layer disposed between the polymeric covering and the exterior surface of the tubular stent structure to attach the polymeric covering to the expandable tubular stent structure.

10. The intraluminal prosthesis of claim 9, wherein the polymeric covering is non-continuously attached to the tubular stent structure with the adhesive layer at discrete areas.

11. The intraluminal prosthesis of claim 9, wherein the polymeric covering is continuously attached to the tubular stent structure with the adhesive layer throughout the entire length of the tubular stent structure.

12. The intraluminal prosthesis of claim 9, wherein the polymeric covering is a preformed covering attached to the tubular stent structure with the adhesive layer subsequent to formation of the polymeric covering.

13. An intraluminal prosthesis comprising:

a radially expandable tubular stent structure having a first end, a second end, and a length extending therebetween, the expandable tubular stent structure having an interior surface, an exterior surface, and a plurality of openings extending through the tubular stent structure from the interior surface to the exterior surface, wherein the tubular stent structure includes a first flared end region at the first end; and

a polymeric covering surrounding the tubular stent structure and covering the plurality of openings, the polymeric covering having a first end at the first end of the tubular stent structure and a second end at the second end of the tubular stent structure such that the polymeric covering extends along the entire length of the tubular stent structure;

an adhesive layer disposed between the polymeric covering and the exterior surface of the tubular stent structure to attach the polymeric covering to the expandable tubular stent structure;

wherein the polymeric covering is a preformed covering attached to the tubular stent structure with the adhesive layer subsequent to formation of the polymeric covering;

wherein the polymeric covering includes a plurality of projections extending radially outward from an outer surface of the polymeric covering, wherein an inner surface of the polymeric covering opposite each projection is devoid of projections or recesses along the entire length of the tubular stent structure, the plurality of projections arranged circumferentially around the first flared end region, wherein the plurality of projections include a plurality of polymeric annular rings integrally formed with the polymeric covering, the plurality of projections integrally formed with the polymeric covering, the plurality of projections configured to contact an inner surface of a body lumen to prevent migration of the prosthesis in the body lumen.

14. The intraluminal prosthesis of claim 13, wherein the polymeric covering is non-continuously attached to the tubular stent structure with the adhesive layer at discrete areas.

15. The intraluminal prosthesis of claim 13, wherein the polymeric covering is continuously attached to the tubular stent structure with the adhesive layer throughout the entire length of the tubular stent structure.

16. The intraluminal prosthesis of claim 13, wherein the tubular stent structure includes a second flared end region at the second end, wherein the plurality of projections are arranged circumferentially around the first and second flared end regions.

17. The intraluminal prosthesis of claim 13, wherein the plurality of projections are a plurality of beads spaced apart circumferentially around the tubular stent structure.