Methods and apparatuses for flow restoration and implanting members in the human body

• US 10,426,644 B2
• Filed: 05/06/2015
• Issued: 10/01/2019
• Est. Priority Date: 10/01/2010
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Shrivastava, Sanjay, Cam, Anh
• Primary Examiner(s): Tyson, Melanie R
• Application Number:
  US14/705,019
• Publication Number:
  US 20150297375A1
• Time in Patent Office: 1,609 Days
• Field of Search: 606159, 606200
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61F 2/844 folded prior to deployment
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/92 Stents in the form of a rolled-up sheet expanding after insertion into the vessel , e.g. with a spiral shape in cross-section
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/962 having an outer sleeve
• CPC Class Codes: A61F 2002/9505 having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
• CPC Class Codes: A61F 2002/9534 for repositioning of stents
• CPC Class Codes: A61F 2210/0076 multilayered, e.g. laminated structures

Abstract

A medical device for blood flow restoration and/or for use as an implantable member in a human vessel includes a self-expanding member, a guidewire, and a connection mechanism. The self-expanding member includes a plurality of cells and filaments having specific ranges of thicknesses, widths, and heights. The self-expanding member can take on a volume-reduced coiled form with overlapped edges, and can generate optimal radial forces against a vessel wall and/or thrombus when deployed and expanded.

Claims

1. A medical device comprising:

a guidewire having a proximal end and a distal end;

a connection mechanism; and

a self-expanding member attached to the distal end of the guidewire via the connection mechanism, the self-expanding member being non-detachable from the guidewire, wherein the self-expanding member has a mesh configuration and comprises;

a proximal portion having a first plurality of cells, the proximal portion being tapered along a longitudinal portion of its length; and

a distal portion having a second plurality of cells, the distal portion forming a generally tube-like configuration having a central, longitudinal axis; and

wherein the first plurality of cells comprises filaments having a filament thickness of between 0.045 mm and 0.080 mm, and a filament width of between 0.040 mm and 0.090 mm;

wherein the second plurality of cells comprises filaments having a filament thickness of between 0.040 mm and 0.075 mm, and a filament width of between 0.038 mm and 0.082 mm;

wherein the self-expanding member has a radial force measurement greater than or equal to 0.0010 N/mm; and

wherein a plurality of independent filament ends are bent and project distally and radially inwardly toward the central, longitudinal axis.

2. The medical device of claim 1, wherein the second plurality of cells comprises cells having a width of between 3.50 mm to 5.50 mm and a height of between 2.50 mm to 4.5 mm.

3. The medical device of claim 1, wherein the connection mechanism comprises an interface or point between the guidewire and self-expanding member.

4. The medical device of claim 1, wherein the second plurality of cells comprises filaments that have an average thickness of between 0.048 mm and 0.067 mm, and an average width of between 0.053 mm and 0.067 mm.

5. The medical device of claim 1, wherein the distally and radially inwardly projecting filaments are bent radially inwardly at an angle between approximately ten to thirty degrees.

6. The medical device of claim 1, further comprising a seam oriented along a longitudinal axis of the distal portion or at an angle relative to the longitudinal axis of the distal portion, the seam forming two edges extending generally longitudinally along the self-expanding member or at an angle relative to the longitudinal axis of the self-expanding member.

7. The medical device of claim 6, wherein the self-expanding member can be modified into a volume-reduced form having a generally coiled, tubular configuration for insertion within a microcatheter, the edges of the distal portion being overlapped in the volume-reduced coiled configuration such that in the volume-reduced coiled configuration the self-expanding member has multiple layers in at least one radial direction.

8. The medical device of claim 1, wherein at least some of the distally and radially inwardly projecting filaments comprise distal elements.

9. The medical device of claim 8, wherein distal elements comprise markers.

10. The medical device of claim 9, wherein the markers comprise marker bands.

11. A medical device comprising:

a guidewire having a proximal end and a distal end; and

a self-expanding member attached to the distal end of the guidewire, the self-expanding member being non-detachable from the guidewire, the self-expanding member comprising;

a proximal portion having a first plurality of cells, the proximal portion being tapered along a longitudinal portion of its length;

a tubular distal portion having a central, longitudinal axis and a second plurality of cells; and

wherein the first plurality of cells comprises filaments having a filament thickness of between 0.045 mm and 0.080 mm, and a filament width of between 0.040 mm and 0.090 mm;

wherein the second plurality of cells comprises filaments having a filament thickness of between 0.040 mm and 0.075 mm, and a filament width of between 0.038 mm and 0.082 mm;

wherein the self-expanding member has a radial force measurement greater than or equal to 0.0010 N/mm; and

wherein a plurality of independent filament ends are bent and project distally and radially inwardly toward the central, longitudinal axis.

12. The medical device of claim 11, wherein the second plurality of cells comprises cells having a width of between 3.50 mm to 5.50 mm and a height of between 2.50 mm to 4.5 mm.

13. The medical device of claim 11, wherein the second plurality of cells comprises filaments that have an average thickness of between 0.048 mm and 0.067 mm, and an average width of between 0.053 mm and 0.067 mm.

14. The medical device of claim 11, wherein the distally and radially inwardly projecting filaments are bent radially inwardly at an angle between approximately ten to thirty degrees.

15. The medical device of claim 11, further comprising a seam oriented along a longitudinal axis of the distal portion or at an angle relative to the longitudinal axis of the distal portion, the seam forming two edges extending generally longitudinally along the self-expanding member or at an angle relative to the longitudinal axis of the self-expanding member.

16. The medical device of claim 15, wherein the self-expanding member can be modified into a volume-reduced form having a generally coiled, tubular configuration for insertion within a microcatheter, the edges of the distal portion being overlapped in the volume-reduced coiled configuration such that in the volume-reduced coiled configuration the self-expanding member has multiple layers in at least one radial direction.

17. The medical device of claim 11, wherein at least some of the distally and radially inwardly projecting filaments comprise distal elements.

18. The medical device of claim 17, wherein distal elements comprise markers.

19. The medical device of claim 18, wherein the markers comprise marker bands.