Systems, devices, and methods including implantable devices with anti-microbial properties
First Claim
Patent Images
1. An insertable device, comprising:
- a body structure having an outer surface and an inner surface defining one or more fluid-flow passageways;
circuitry configured to detect one or more microorganisms present proximate at least one of the outer surface, the inner surface, or the one or more fluid-flow passageways; and
one or more actively controllable anti-microbial regions included on at least one of the outer surface or the inner surface, or embedded in the body structure, at least one of the one or more actively controllable anti-microbial regions having a wettability switchable feature configured to actuate between a first anti-microbial state and a second anti-microbial state responsive to detection of at least one microorganism by the circuitry.
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Abstract
Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.
384 Citations
30 Claims
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1. An insertable device, comprising:
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a body structure having an outer surface and an inner surface defining one or more fluid-flow passageways; circuitry configured to detect one or more microorganisms present proximate at least one of the outer surface, the inner surface, or the one or more fluid-flow passageways; and one or more actively controllable anti-microbial regions included on at least one of the outer surface or the inner surface, or embedded in the body structure, at least one of the one or more actively controllable anti-microbial regions having a wettability switchable feature configured to actuate between a first anti-microbial state and a second anti-microbial state responsive to detection of at least one microorganism by the circuitry. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. An insertable device, comprising:
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a body structure having an outer surface and an inner surface defining one or more fluid-flow passageways; circuitry configured to detect one or more microorganisms present proximate at least one of the outer surface, the inner surface, or the one or more fluid-flow passageways; and one or more actively controllable anti-microbial regions included on at least one of the outer surface or the inner surface, or embedded in the body structure, at least one of the one or more actively controllable anti-microbial regions having a structure configured to actuate between a first anti-microbial state and a second anti-microbial state responsive to detection of at least one microorganism by the circuitry, wherein the structure includes at least a first nanostructure and a second nanostructure, the structure configured to at least one of extend or contract at least one of the first nanostructure or the second nanostructure responsive to detection of at least one microorganism by the circuitry, to increase a spacing between the first nanostructure and the second nanostructure responsive to detection of at least one microorganism by the circuitry, or to decrease a spacing between the first nanostructure and the second nanostructure responsive to detection of at least one microorganism by the circuitry.
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17. An insertable device, comprising:
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a body structure having an outer surface and an inner surface defining one or more fluid-flow passageways; one or more actively controllable anti-microbial regions included on at least one of the outer surface or the inner surface, or embedded in the body structure, at least one of the one or more actively controllable anti-microbial regions having a wettability switchable feature configured to actuate between a first anti-microbial state and a second anti-microbial state; and circuitry configured to actuate the wettability switchable feature responsive to detection of at least one microorganism proximate at least one of the outer surface, the inner surface, or the one or more fluid-flow passageways. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification