Disposable diagnostic device with vented priming fluid passage for volumetric control of sample and reagents and method of performing a diagnosis therewith
First Claim
1. A disposable diagnostic device, comprising:
- a body having a sample receiving chamber, configured for receipt of a fluid sample, and an analysis chamber;
a rupturable fluid dispensing member operably fixed to said body and containing a fluid therein; and
a valve member coupled to said body for selective translatable movement from a first state to a second state, said valve member having a fluid passage extending between an inlet and an outlet with a hydroscopic, gas permeable first vent covering at least a portion of said fluid passage, said fluid passage being out of fluid communication with said sample receiving chamber and in fluid communication, upon said fluid dispensing member being ruptured, with said fluid in said fluid dispensing member while in said first state, said first vent preventing fluid from passing therethrough and allowing air to vent outwardly from said fluid passage while a priming volume of the fluid flows from said fluid dispensing member through said outlet into said fluid passage in said first state, said outlet of said fluid passage being brought into fluid communication with said sample receiving chamber and said inlet being brought into fluid communication with said rupturable fluid dispensing member in said second state to allow said priming volume of fluid within said fluid passage to transport the fluid sample to said analysis chamber.
2 Assignments
0 Petitions
Accused Products
Abstract
A diagnostic cartridge and method of performing a diagnostic test are provided. The cartridge includes a body having a sample chamber for receipt of a sample, an analysis chamber, and a reagent-containing dispensing member. A valve member is coupled to the body for selective movement between first and second states. The valve member has a fluid passage with a hydroscopic, gas permeable vent. In the first state, the fluid passage is out of fluid communication with the sample chamber and is registered for fluid communication with the reagent-containing dispensing member. The vent prevents fluid from passing therethrough and allows air to vent therefrom as reagent flows into and fills the fluid passage. In the second state, the fluid passage remains in fluid communication with the reagent-containing dispensing member and is brought into fluid communication with the sample chamber to facilitate transporting the sample to the analysis chamber.
12 Citations
15 Claims
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1. A disposable diagnostic device, comprising:
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a body having a sample receiving chamber, configured for receipt of a fluid sample, and an analysis chamber; a rupturable fluid dispensing member operably fixed to said body and containing a fluid therein; and a valve member coupled to said body for selective translatable movement from a first state to a second state, said valve member having a fluid passage extending between an inlet and an outlet with a hydroscopic, gas permeable first vent covering at least a portion of said fluid passage, said fluid passage being out of fluid communication with said sample receiving chamber and in fluid communication, upon said fluid dispensing member being ruptured, with said fluid in said fluid dispensing member while in said first state, said first vent preventing fluid from passing therethrough and allowing air to vent outwardly from said fluid passage while a priming volume of the fluid flows from said fluid dispensing member through said outlet into said fluid passage in said first state, said outlet of said fluid passage being brought into fluid communication with said sample receiving chamber and said inlet being brought into fluid communication with said rupturable fluid dispensing member in said second state to allow said priming volume of fluid within said fluid passage to transport the fluid sample to said analysis chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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Specification