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Chiral auxiliaries

  • US 10,428,019 B2
  • Filed: 09/22/2011
  • Issued: 10/01/2019
  • Est. Priority Date: 09/24/2010
  • Status: Active Grant
First Claim
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1. A nucleic acid derivative comprising a chiral auxiliary, wherein the chiral auxiliary is represented by formula (II) and binds to a phosphorus atom of a phosphite moiety of the nucleic acid derivative through the oxygen atom of the chiral auxiliary, wherein the squiggly line represents the point of attachment to a phosphorus atom of a phosphite moiety of the nucleic acid derivative:

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