Scanning system

• US 10,434,331 B2
• Filed: 04/20/2017
• Issued: 10/08/2019
• Est. Priority Date: 02/20/2014
• Status: Active Grant

• Current Assignee: Mevion Medical Systems Incorporated
• Original Assignee: Mevion Medical Systems Incorporated
• Inventors: O'Neal, III, Charles D., Molzahn, Adam C.
• Primary Examiner(s): Stoffa, Wyatt A
• Application Number:
  US15/492,132
• Publication Number:
  US 20170281968A1
• Time in Patent Office: 901 Days
• CPC Class Codes: A61N 2005/1085 characterised by the type of particles applied to the patient
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/103 Treatment planning systems
• CPC Class Codes: A61N 5/1043 Scanning the radiation beam, e.g. spot scanning or raster scanning
• CPC Class Codes: A61N 5/1048 Monitoring, verifying, controlling systems and methods
• CPC Class Codes: A61N 5/1049 for verifying the position of the patient with respect to the radiation beam
• CPC Class Codes: A61N 5/1065 Beam adjustment
• CPC Class Codes: A61N 5/1067 in real time, i.e. during treatment
• CPC Class Codes: A61N 5/1071 for verifying the dose delivered by the treatment plan
• CPC Class Codes: A61N 5/1081 Rotating beam systems with a specific mechanical construction, e.g. gantries
• CPC Class Codes: H05H 13/02 Synchrocyclotrons, i.e. frequency modulated cyclotrons
• CPC Class Codes: H05H 13/04 Synchrotrons
• CPC Class Codes: H05H 2007/002 for modifying beam trajectory, e.g. gantries
• CPC Class Codes: H05H 2007/004 for modifying beam energy, e.g. spread out Bragg peak devices
• CPC Class Codes: H05H 2007/048 for modifying beam trajectory, e.g. gantry systems
• CPC Class Codes: H05H 7/04 Magnet systems , e.g. undulators, wigglers free-electron laser H01S3/0903; Energisation thereof

Abstract

An example particle therapy system includes: a particle accelerator to output a beam of charged particles; and a scanning system to scan the beam across at least part of an irradiation target. An example scanning system includes: a scanning magnet to move the beam during scanning; and a control system (i) to control the scanning magnet to produce uninterrupted movement of the beam over at least part of a depth-wise layer of the irradiation target so as to deliver doses of charged particles to the irradiation target; and (ii) to determine, in synchronism with delivery of a dose, information identifying the dose actually delivered at different positions along the depth-wise layer.

Claims

1. A particle therapy system comprising:

a particle accelerator to output a beam of charged particles, the particle accelerator being configured to produce the beam in accordance with a radio frequency (RF) cycle; and

a scanning system to perform scanning on at least part of an irradiation target, the scanning system comprising;

a scanning magnet to move the beam across the at least part of the irradiation target during scanning, where movement of the beam is based on a current of the scanning magnet; and

a control system (i) to control the current of the scanning magnet independently of the RF cycle in order to move the beam across the at least part of the irradiation target to deliver doses of charged particles, (ii) for positions on the irradiation target at which the particle beam delivers a dose of charged particles, to store information identifying a location and an amount of the dose delivered, (iii) to compare a cumulative dose delivered at each position to a target cumulative dose, and (iv) if the cumulative dose does not match the target cumulative dose at specific positions, to control the current of the scanning magnet in order to move the beam so as to deliver additional dose to the specific positions.

2. The particle therapy system of claim 1, wherein the control system is configured to measure the cumulative dose delivered at each position;

and

wherein measuring the cumulative dose delivered at each position is substantially synchronous with the RF cycle.

3. The particle therapy system of claim 1, wherein the control system is configured to measure the cumulative dose delivered at each position;

and

wherein measuring the cumulative dose delivered at each position is substantially synchronous with delivery of dose at each position.

4. The particle therapy system of claim 1, wherein the information comprises an amount of dose delivered at each position and at least one of:

a location of each position within the irradiation target or a magnet current corresponding to each position within the irradiation target.

5. The particle therapy system of claim 1, wherein the location corresponds to three-dimensional coordinates for the irradiation target.

6. The particle therapy system of claim 1, wherein the particle therapy system further comprises:

memory to store a treatment plan that identifies, for each position, a target cumulative dose of charged particles, the treatment plan omitting information about individual doses of charged particles to be delivered to individual positions during scanning to achieve the target cumulative dose.

7. The particle therapy system of claim 1, wherein the scanning system further comprises:

a degrader to change an energy of the beam prior to the beam reaching the irradiation target, the degrader being down-beam of the scanning magnet relative to the particle accelerator;

wherein the control system is configured to control movement of at least part of the degrader into, or out of, a path of the beam during scanning in order to affect the energy of the beam and thereby set a layer of the irradiation target to which charged particles are to be delivered.

8. The particle therapy system of claim 7, wherein the particle accelerator comprises an ion source to provide pulses of charged particles, the pulses of charged particles forming the beam;

and

wherein, during at least part of the movement of the degrader, the ion source is deactivated.

9. The particle therapy system of claim 7, wherein the particle accelerator comprises:

an ion source to provide pulses of charged particles, the pulses of charged particles forming the beam; and

a voltage source to provide an RF voltage at the RF cycle to a cavity to accelerate the charged particles, the cavity having a magnetic field for causing the charged particles to move orbitally within the cavity;

wherein, during at least part of the movement of the degrader, the voltage source is deactivated.

10. The particle therapy system of claim 9, wherein, during the movement of the at least part of the degrader, the ion source is deactivated at a same time that the voltage source is deactivated.

11. The particle therapy system of claim 1, wherein the particle accelerator is a variable-energy particle accelerator;

and

wherein the control system is configured to set an energy level of the particle accelerator prior to scanning, the energy level comprising an energy level of the beam.

12. The particle therapy system of claim 1, wherein the particle accelerator is a variable-energy particle accelerator;

and

wherein the control system is configured to change an energy level of the particle accelerator during scanning, the energy level comprising an energy level of the beam.

13. The particle therapy system of claim 1, wherein, for a target position at which the particle beam delivers a dose of charged particles, multiple individual deliveries of the dose of charged particles comprise a percentage of a total cumulative dose at the target position.

14. The particle therapy system of claim 13, wherein the percentage is less than 100% of the total cumulative dose at the target position.

15. The particle therapy system of claim 13, wherein the percentage is about 100% of the total cumulative dose at the target position.

16. The particle therapy system of claim 1, wherein the scanning magnet has an air core.

17. The particle therapy system of claim 1, wherein the scanning magnet has a ferromagnetic core.

18. The particle therapy system of claim 1, further comprising:

a gantry on which the particle accelerator is mounted, the gantry for rotating the particle accelerator around the irradiation target;

wherein the control system is configured to control the scanning system based on a rotational angle of the gantry.

19. The particle therapy system of claim 1, wherein the particle accelerator is a synchrocyclotron;

and

wherein the beam is a pulsed beam comprised of pulses of charged particles, the charged particles in the beam being output from the synchrocyclotron in accordance with the RF cycle.

20. A particle therapy system comprising:

a particle accelerator to output a beam of charged particles, the particle accelerator being configured to produce the beam in accordance with a radio frequency (RF) cycle; and

a scanning system to perform scanning on least part of an irradiation target, the scanning system comprising;

a scanning magnet to move the beam across the at least part of the irradiation target during scanning, where movement of the beam is based on a current of the scanning magnet; and

a control system (i) to control the current of the scanning magnet independently of the RF cycle in order to move the beam across the at least part of the irradiation target so as to deliver doses of charged particles to positions on the irradiation target; and

(ii) to determine, in synchronism with delivery of a dose of charged particles to a position on the irradiation target, information identifying an amount of the dose actually delivered to the position.

21. The particle therapy system of claim 20, wherein the particle accelerator is configured to output pulses of charged particles in accordance with the RF cycle, the pulses of charged particles forming the beam.

22. The particle therapy system of claim 20, further comprising:

a gantry on which the particle accelerator is mounted, the gantry for rotating the particle accelerator around the irradiation target;

wherein the control system is configured to control the scanning system based on a rotational angle of the gantry.

23. The particle therapy system of claim 22, wherein the scanning magnet comprises an air core;

and

wherein controlling the scanning system based on a rotational angle of the gantry comprises controlling the current of the scanning magnet based on the rotational angle of the gantry.

24. The particle therapy system of claim 20, further comprising:

a gantry on which the particle accelerator is mounted, the gantry for rotating the particle accelerator around the irradiation target;

wherein the scanning magnet comprises a ferromagnetic core.

25. The particle therapy system of claim 20, wherein there is a linear correlation between the current of the scanning magnet and the movement of the beam during at least part of the movement of the beam.

26. The particle therapy system of claim 20, wherein the control system is configured to measure a cumulative dose of charged particles delivered to positions on the irradiation target;

and

wherein measuring the cumulative dose delivered at each of the positions is substantially synchronous with the RF cycle.

27. The particle therapy system of claim 20, wherein the scanning magnet comprises a core comprised of both air and ferromagnetic material.

28. The particle therapy system of claim 27, further comprising:

a gantry on which the particle accelerator is mounted, the gantry for rotating the particle accelerator around the irradiation target;

wherein the control system is configured to control the scanning system based on a rotational angle of the gantry.

29. The particle therapy system of claim 22, wherein controlling the scanning system based on a rotational angle of the gantry comprises controlling the current of the scanning magnet based on the rotational angle of the gantry.

30. The particle therapy system of claim 20, further comprising:

a range modulator comprising plates configured to move into, and out of, a path of the particle beam during scanning of the irradiation target.

31. The particle therapy system of claim 20, wherein the control system is configured to change an intensity of the beam for different scans of the particle beam.

32. The particle therapy system of claim 31, wherein the control system is configured to cause the beam to move across the at least part of the irradiation target multiple times;

and

wherein, for different times that the beam moves across the at least part of the irradiation target, the control system is configured to change the intensity of the beam.

33. The particle therapy system of claim 20, wherein the particle therapy system further comprises:

memory to store a treatment plan that identifies, for each position to which a dose is to be delivered on the irradiation target, a target cumulative dose of charged particles, the treatment plan omitting information about individual doses of charged particles to be delivered to individual positions during scanning to achieve the target cumulative dose;

wherein the scanning system is configured to perform scanning based on the treatment plan.

34. The particle therapy system of claim 20, wherein determining the information identifying an amount of the dose actually delivered to the position comprises measuring the amount of the dose actually delivered to the position as the dose is delivered.