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Automated control of cell growth rates for induction and transformation

  • US 10,435,662 B1
  • Filed: 03/21/2019
  • Issued: 10/08/2019
  • Est. Priority Date: 03/29/2018
  • Status: Active Grant
First Claim
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1. A cell growth device comprising:

  • a housing;

    a motor;

    a thermal control device;

    a spectrophotometer;

    a processor;

    an electrical connection configured to be electrically coupled to the thermal control device; and

    a rotating growth vial comprisinga vial;

    a drive engagement mechanism configured to engage with the motor to spin the vial; and

    a light path through the vial for a light beam generated by the spectrophotometer, wherein the spectrophotometer is configured to measure and deliver to the processor an optical density of cells in the vial;

    wherein the processor accepts input from a user, receives from the spectrophotometer the optical density of the cells in the vial, and through the electrical connection directs the thermal control device to adjust the temperature of the vial to grow the cells to a target value at a target time; and

    wherein the processor is programmed to use wavelength values for blanks commensurate with growth medium in the vial.

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