Methods and systems for assisting persons, product providers and/or service providers

• US 10,441,202 B2
• Filed: 05/23/2014
• Issued: 10/15/2019
• Est. Priority Date: 05/23/2013
• Status: Active Grant

• Current Assignee: Capia Ip, Co.
• Original Assignee: Iphenotype LLC
• Inventors: Short, Jay M., Briggs, Steve
• Primary Examiner(s): Hong, Thomas J
• Application Number:
  US14/892,186
• Publication Number:
  US 20160374600A1
• Time in Patent Office: 1,971 Days
• Field of Search: 434236
• CPC Class Codes: A61B 3/113 for determining or recording eye movement
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/165 Evaluating the state of mind, e.g. depression, anxiety
• CPC Class Codes: A61B 5/4875 Hydration status, fluid retention of the body
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: G06F 16/285 Clustering or classification
• CPC Class Codes: G06F 16/9535 Search customisation based on user profiles and personalisation
• CPC Class Codes: G06Q 30/02 Marketing; Price estimation or determination; Fundraising
• CPC Class Codes: G06Q 30/0631 Item recommendations
• CPC Class Codes: G09B 19/00 Teaching not covered by other main groups of this subclass teaching or practice apparatus for gun-aiming or gun-laying F41G3/26
• CPC Class Codes: G09B 5/12 different stations being capable of presenting different information simultaneously G09B5/14 takes precedence
• CPC Class Codes: G16B 20/00 ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
• CPC Class Codes: G16B 20/20 Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
• CPC Class Codes: G16B 40/00 : ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
• CPC Class Codes: G16B 40/30 : Unsupervised data analysis
• CPC Class Codes: G16H 10/20 : for electronic clinical trials or questionnaires
• CPC Class Codes: G16H 20/00 : ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
• CPC Class Codes: G16H 40/63 : for local operation
• CPC Class Codes: G16H 50/70 : for mining of medical data, e.g. analysing previous cases of other patients

Abstract

A method of assisting daily living for an individual, comprising the steps of measuring a presence and/or concentration of one or more biomarkers in a sample from the individual; predicting a behavior or emotional state of the individual based on the measured presence and/or concentration of the one or more biomarkers by applying a correlation between human biological phenotype and human behavioral and/or emotional phenotype; and altering the living environment of the individual or providing information, advice or guidance to the individual based on the predicted behavior or emotional state of the individual, where the correlation between human biological phenotype and human behavioral and/or emotional phenotype comprises a correlation between the one or more biomarkers and a behavior or emotional state. A system for assisting daily living for an individual is also provided. The present invention is useful for product and service providers and industries for purposes of standardizing or rating product quality and efficacy, and/or for promotion and selling purposes.

Claims

1. A method of assisting daily living of an individual, comprising the steps of:

measuring a presence and/or concentration of at least two biomarkers comprising a polypeptide and a metabolite in a urine sample from the individual with a measuring device located in a urinal or toilet;

predicting a behavior or emotional state of the individual based on the measured presence and/or concentration of the at least two biomarkers comprising a polypeptide and a metabolite by applying a correlation between human biological phenotype and human behavioral and/or emotional phenotype; and

altering the living environment of the individual based on the predicted behavior or emotional state of the individual,

wherein the correlation between human biological phenotype and human behavioral and/or emotional phenotype comprises a correlation between the at least two biomarkers comprising a polypeptide and a metabolite and a behavior or emotional state.

2. The method of claim 1, wherein the at least two biomarkers further comprises at least one of polynucleotides, microbes, inorganic compounds, and ions.

3. The method of claim 2, wherein the presence or concentration of the at least two biomarkers is measured by using recognition molecules selected from antibodies, antigens, aptamers, natural receptors, synthetic receptors, ligands, enzymes, enzymatic substrates, nuclei acid probes.

4. The method of claim 2, wherein the measuring step is carried out using one or more biosensors comprising a transducer selected from optical transducers, mass-based transducers, magnetic field based transducers, electrochemical transducers, and calorimetric transducers.

5. The method of claim 2, wherein the presence or concentration of at least two biomarkers in the sample is measured by one or more electrodes selected from potentiometric electrodes, amperometric electrodes and conductometric electrodes.

6. The method of claim 2, wherein the presence or concentration of the at least two biomarkers is measured by an array of recognition molecules selected from antibodies, aptamers, oligonucleotides and combinations thereof.

7. The method of claim 1, wherein the measuring step further comprises measuring a physiological parameter of the individual selected from body temperature, pulse rate, blood pressure, respiratory rate, hydration status, electromuscular activity, eye movement and combinations thereof.

8. The method of claim 1, wherein the presence and/or concentration measured in said measuring step is correlated with location data associated with a location wherein said measurement is made.

9. The method of claim 8, wherein the location data is data associated with the location selected from temperature, altitude noise, altitude, wind, humidity, pollution, oxygen, sunshine, pollen, crowd density, concrete, grass, night, day, near highway and traffic density at that time, aircraft flying, cosmic radiation levels, radon exposure, clothing and combinations thereof.

10. The method of claim 1, wherein altering the living environment of the individual comprises an alteration selected from adjusting brightness and/or color of lighting, adjusting room temperature, adjusting humidity, rearranging furniture, playing music, adjusting a volume of music or audio, changing a TV channel, playing a recorded voice or sound, changing an appearance of a wall or screen, retracting a roof, opening or closing a window, adjusting oxygen concentration in air, adding or adjusting a scent in air, introducing one or more air-borne chemicals into air, and altering one or more of a display and web search results.

11. The method of claim 1, further comprising the step of providing information, advice or guidance to the individual, wherein the information, advice or guidance comprises a course of action selected from a course of action for performing the predicted behavior, a course of action for preventing or mitigating the predicted behavior, a course of action for better coping with the predicted emotional state and combinations thereof.

12. The method of claim 1, further comprising the step of providing information, advice or guidance to the individual, wherein the information, advice or guidance comprises

suggesting one or more products selected from supplements, vitamins, beverages, beauty products, personal care products, weight loss products, skin care products, sports supplements, extracts, probiotics, seasonings, flavors, sweeteners, taste/aroma blockers/modifiers, bulking agents, video games, electronics, reading materials, music, movies, TV programs, live shows, apparel, accessories, footwear, home appliances, exercise equipment, types of food, boats, automobiles, bikes, restaurants, office supplies, furniture, and vacation resorts/destinations;

suggesting one or more services selected from messaging, financial services, dating services, catering services, home cleaning services, home improvement services, hair dressing services, cosmetic services, professional counseling services, travel services, casino gaming services, shopping services, real estate services, sports-related services, entertainment services, online auction services and hospitality services;

or

suggesting at least one promotion or coupon for a product or service.

13. The method of claim 12, further comprising the step of suggesting a local business and/or providing a map location of a local business in relation to the information, advice or guidance, wherein the information, advice or guidance involves suggesting a product or a service, and the local business provides the suggested product or service.

14. A system for assisting an individual in daily living, comprising:

a measuring device located in a toilet or urinal for measuring a presence and/or concentration of at least two biomarkers comprising a polypeptide and a metabolite in a urine sample from the individual;

a predictor for predicting a behavior or emotional state of the individual based on the measured presence and/or concentration of the at least two biomarkers comprising a polypeptide and a metabolite by applying a correlation between human biological phenotype and human behavioral and/or emotional phenotype;

an assistance device for altering the living environment of the individual based on the predicted behavior or emotional state of the individual; and

a database for storing correlations between human biological phenotype and human behavioral and/or emotional phenotype, wherein the correlation between human biological phenotype and human behavioral and/or emotional phenotype comprises a correlation between the at least two biomarkers comprising a polypeptide and a metabolite and a behavior or emotional state.

15. The system of claim 14, wherein the predictor and the assistance device are part of an electronic device selected from smartphones, tablet computers, notebook computers, e-book readers, mobile internet devices, personal digital assistants, internet phones, holographic devices, holographic phones, cable internet devices, satellite internet devices, internet televisions, digital subscriber line (DSL) internet devices and remote controls.

16. The system of claim 14, further comprising a supplementary measuring device for measuring at least one physiological parameter selected from body temperature, pulse rate, blood pressure, respiratory rate, hydration status, eye movement, electromuscular activity and combinations thereof.

17. The system of claim 14, further comprising an apparatus for correlating measured presence and/or concentration of the at least two biomarkers with time at a location wherein said measurement is made.

18. The system of claim 17, wherein the predictor considers additional data from the location selected from temperature, altitude noise, altitude, wind, humidity, pollution, oxygen, sunshine, pollen, crowd density, concrete, grass, night, day, near highway and traffic density at that time, aircraft flying, cosmic radiation levels, radon exposure, clothing and combinations thereof that are correlated with one or more measurements taken in said measuring step.

19. The system of claim 14, wherein the measuring device comprises one or more biosensors including a structure selected from a giant magnetoresistance structure, a nanowire, a microfluidic circuit, a nanotube and a biochip.

20. The system of claim 14, wherein the measuring device comprises one or more electrodes selected from potentiometric electrodes, amperometric electrodes and conductometric electrodes.

21. The system of claim 14, wherein the measuring device comprises an array selected from antibody arrays, aptamer arrays, oligonucleotide arrays and combinations thereof.

22. The system of claim 14, wherein the assistance device further provides information, advice or guidance to the individual,

the system further comprises an apparatus for suggesting a local business and/or providing a map location of a local business in relation to the information, advice or guidance, wherein the information, advice or guidance involves suggesting a product or a service, and the local business provides the suggested product or service.

23. The system of claim 14, wherein the system is implemented using an electronic device selected from smartphones, tablet computers, notebook computers, e-book readers, mobile internet devices, personal digital assistants, internet phones, holographic devices, holographic phones, cable internet devices, satellite internet devices, internet televisions, digital subscriber line (DSL) internet devices and remote controls.

24. The system of claim 23, wherein the assistance device further provides information, advice or guidance to the individual, and the electronic device is configured for providing a map location of business in relation to the information, advice or guidance, wherein the information, advice or guidance is suggesting a product or a service, and the business provides the product or service.

25. The system of claim 23, wherein the assistance device further provides information, advice or guidance to the individual, and the electronic device is configured for obtaining feedback on a suggested product or a service, and the feedback is suitable for being used to rank the product or service, and wherein the information, advice or guidance is suggesting the product or service.