Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
First Claim
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1. An inhalation pharmaceutical composition comprising a unit dose of an antiarrhythmic agent in a liquid solution that is therapeutically effective for treating atrial arrhythmia in a human subject in need thereof, wherein said antiarrhythmic agent is selected from the group consisting of:
- flecainide, a salt thereof, and a solvate thereof, wherein said unit dose of said antiarrhythmic agent is about 50 mg to about 350 mg, wherein a concentration of said antiarrhythmic agent in said unit dose is about 35 to about 60 mg/mL, and wherein said pharmaceutical composition is formulated for administration via inhalation.
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Abstract
Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also contemplated.
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Citations
23 Claims
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1. An inhalation pharmaceutical composition comprising a unit dose of an antiarrhythmic agent in a liquid solution that is therapeutically effective for treating atrial arrhythmia in a human subject in need thereof, wherein said antiarrhythmic agent is selected from the group consisting of:
- flecainide, a salt thereof, and a solvate thereof, wherein said unit dose of said antiarrhythmic agent is about 50 mg to about 350 mg, wherein a concentration of said antiarrhythmic agent in said unit dose is about 35 to about 60 mg/mL, and wherein said pharmaceutical composition is formulated for administration via inhalation.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
Specification