Dietary composition and method for preventing, reducing, alleviating or treating idiopathic vomiting

• US 10,441,623 B2
• Filed: 03/06/2014
• Issued: 10/15/2019
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Mars Incorporated
• Original Assignee: Mars Incorporated
• Inventors: Park, Jean Soon, Hu, Ping, Lin, Yakang, Reinsalu, Lori Ann
• Primary Examiner(s): McKelvey, Terry A
• Assistant Examiner(s): Chen, Catheryne
• Application Number:
  US14/198,662
• Publication Number:
  US 20140271943A1
• Time in Patent Office: 2,049 Days
• Field of Search: None
• CPC Class Codes: A61K 36/00 Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines antigens from pollen A61K39/36
• CPC Class Codes: A61K 36/15 Pinaceae (Pine family), e.g. pine or cedar
• CPC Class Codes: A61K 36/16 Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 36/19 Acanthaceae (Acanthus family)
• CPC Class Codes: A61K 36/23 Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
• CPC Class Codes: A61K 36/28 Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• CPC Class Codes: A61K 36/324 Boswellia, e.g. frankincense
• CPC Class Codes: A61K 36/41 Crassulaceae (Stonecrop family)
• CPC Class Codes: A61K 36/45 Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
• CPC Class Codes: A61K 36/47 Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
• CPC Class Codes: A61K 36/48 Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
• CPC Class Codes: A61K 36/484 Glycyrrhiza (licorice)
• CPC Class Codes: A61K 36/53 Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
• CPC Class Codes: A61K 36/54 Lauraceae (Laurel family), e.g. cinnamon or sassafras
• CPC Class Codes: A61K 36/55 Linaceae (Flax family), e.g. Linum
• CPC Class Codes: A61K 36/61 Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
• CPC Class Codes: A61K 36/634 Forsythia
• CPC Class Codes: A61K 36/67 Piperaceae (Pepper family), e.g. Jamaican pepper or kava
• CPC Class Codes: A61K 36/708 Rheum (rhubarb)
• CPC Class Codes: A61K 36/718 : Coptis (goldthread)
• CPC Class Codes: A61K 36/736 : Prunus, e.g. plum, cherry, peach, apricot or almond
• CPC Class Codes: A61K 36/752 : Citrus, e.g. lime, orange or lemon
• CPC Class Codes: A61K 36/77 : Sapindaceae (Soapberry family), e.g. lychee or soapberry
• CPC Class Codes: A61K 36/81 : Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
• CPC Class Codes: A61K 36/82 : Theaceae (Tea family), e.g. camellia
• CPC Class Codes: A61K 36/835 : Aquilaria
• CPC Class Codes: A61K 36/87 : Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
• CPC Class Codes: A61K 36/88 : Liliopsida (monocotyledons)
• CPC Class Codes: A61K 36/889 : Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
• CPC Class Codes: A61K 36/9066 : Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• CPC Class Codes: A61K 36/9068 : Zingiber, e.g. garden ginger
• CPC Class Codes: A61K 45/06 : Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61P 1/08 : for nausea, cinetosis or vertigo; Antiemetics
• CPC Class Codes: A61P 1/12 : Antidiarrhoeals
• CPC Class Codes: A61P 43/00 : Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The present invention relates to compositions containing plant materials or extracts with inhibitory effect on a 5-HT3a and/or NK-1 receptor for preventing or treating idiopathic vomiting.

Claims

1. A method for treating idiopathic vomiting in a companion animal, comprising the step of orally administering to said companion animal one or more plant materials or extracts thereof in an effective amount for inhibiting a 5-hydroxytryptamine-3a serotonin (5-HT3a) receptor and/or a neurokinin-1 (NK-1) receptor, wherein the one or more plant materials or extracts thereof consists of Curcuma longa (turmeric) and licorice, ginger, rhubarb, or a combination thereof.

2. The method of claim 1, wherein said plant materials or extracts are orally administered to the companion animal as a part of a dietary composition.

3. The method of claim 2, wherein said dietary composition is a pet food comprising from 0.1 ppm to 75,000 ppm of said plant materials or extracts thereof, and wherein said pet food further comprises a source of carbohydrate, a source of protein, and optionally a source of fat.

4. The method of claim 2, wherein said dietary composition is a pet food supplement comprising from 0.1% to 99% of said plant materials or extracts thereof by weight, and wherein the step of orally administering comprises feeding the pet food supplement to the companion animal either separately from or in combination with a pet food.

5. The method of claim 2, wherein said dietary composition is orally administered to the companion animal at a frequency ranging from once a month to six times a day.

6. The method of claim 2, wherein said dietary composition is orally administered to the companion animal for a duration ranging from five days to twenty five years.