Delivery devices and methods

• US 10,441,761 B2
• Filed: 06/29/2017
• Issued: 10/15/2019
• Est. Priority Date: 07/01/2016
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Christakis, Laura, Peterson, Ashleigh, Bean, Jeffrey, Clerc, Claude, Pic, Andrew, Fredrickson, Gerald, Gilbert, Stan, Smith, Amanda, Vega, Jose
• Primary Examiner(s): Stigell, Theodore J
• Application Number:
  US15/637,743
• Publication Number:
  US 20180001067A1
• Time in Patent Office: 838 Days
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 2017/00676 promotion of self-sealing of the puncture
• CPC Class Codes: A61M 1/304 Treatment chamber used as reservoir, e.g. centrifuge bowl or filter with movable membrane
• CPC Class Codes: A61M 11/007 Syringe-type or piston-type sprayers or atomisers
• CPC Class Codes: A61M 11/02 operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised sprayers for horticulture A01G, A01H; killing insects A01M; air humidifying by nozzles F24F6/14, F24F6/18; cooling by spraying F28B, F28C
• CPC Class Codes: A61M 13/00 Insufflators for therapeutic or disinfectant purposes , i.e. devices for blowing a gas, powder or vapour into the body hand-held units in which gas flow is produced by muscular energy at the moment of use B05B11/062
• CPC Class Codes: A61M 15/0008 rotating by airflow
• CPC Class Codes: A61M 2202/0007 introduced into the body
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 2206/11 Laminar flow
• CPC Class Codes: A61M 2206/16 Rotating swirling helical flow, e.g. by tangential inflows
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50

Abstract

Implementations of a delivery device and method are disclosed. One implementation is a delivery device comprising a flow chamber with an inlet port for receiving a fluid flow in the flow chamber, and an outlet port for exiting a material from the flow chamber. The flow chamber may include a formation portion in which a suspension of the material is formed, and a collection portion that directs the suspension toward and/or into the outlet port. An amount of the material may collect in the collection portion adjacent the outlet port. The device may further comprise an insertion port for permitting insertion of the material in the flow chamber, and/or a pusher operable to move the amount of material through the outlet port. Related devices and methods also are disclosed.

Claims

1. A device comprising:

a flow chamber including an inlet port for receiving a fluid flow in the flow chamber, and an outlet port for exiting a material from the flow chamber;

a formation portion of the flow chamber in which a suspension of the material is formed;

a collection portion of the flow chamber that directs the suspension toward the outlet port, wherein an amount of the material collects in the collection portion adjacent the outlet port; and

a pusher operable to move the amount of material through the outlet port, wherein the pusher is biased toward or away from the outlet port by a resilient element, wherein the pusher is configured to move between a first position outside the outlet port and a second position at least partially within the outlet port when the resilient element moves from a compressed state to an expanded state, wherein a distalmost end of the pusher is configured to contact the material to move the material toward the outlet port, wherein the pusher is longitudinally aligned with a central longitudinal axis of the outlet port.

2. The device of claim 1, wherein the outlet port is in communication with an exit lumen, and the distal end of the pusher is movable through a portion of the exit lumen.

3. The device of claim 1, wherein the formation portion includes a semi-spherical surface defining a volume in which the fluid flow expands.

4. The device of claim 3, wherein the formation portion includes a semi-frustoconical surface that funnels the suspension towards the collection portion.

5. The device of claim 1, further comprising a stopper movable between a first position to compress the resilient element, and a second position to release the resilient element.

6. The device of claim 1, further comprising a sheath extending distally from the outlet port, wherein the pusher is operable to push the amount of material into the sheath, and a distal end of the sheath includes at least one opening configured to distribute the amount of material.

7. The device of claim 6, wherein the at least one opening of the distal end of the sheath is moveable between an open position and a closed position.

8. The device of claim 6, further comprising a removable plug or cap for the at least one opening of the distal end of the sheath.

9. The device of claim 6, wherein at least the distal end of the sheath includes a hydrophilic coating.

10. The device of claim 1, wherein an interior surface of the flow chamber is configured to cause turbulent fluid flow or a vortex.

11. The device of claim 1, wherein the pusher includes a stopper portion protruding from a radially outer surface of pusher, wherein a body defining the flow chamber includes an offshoot configured to allow the stopper portion to pass through the offshoot, wherein alignment of the stopper portion and the offshoot is configured to cause the resilient member to move from the compressed state to the expanded state.

12. A device comprising:

a body defining a flow chamber with an inlet port for receiving a fluid flow in the flow chamber;

an insertion port on the body for receiving a material in the flow chamber;

an outlet port on the body for exiting the material from the flow chamber; and

a pusher operable to move the material out of the outlet port, wherein the pusher is biased toward or away from the outlet port by a resilient element, wherein the pusher is configured to move between a first position outside the outlet port and a second position at least partially within the outlet port when the resilient element moves from a compressed state to an expanded state, wherein a distalmost end of the pusher is configured to contact the material to move the material toward the outlet port, wherein the pusher is longitudinally aligned with a direction of the fluid flow through the outlet port and configured to move through the flow chamber in the direction of the fluid flow through the outlet port;

wherein the fluid flow forms a suspension of the material in the flow chamber, an amount of the material collects in the flow chamber adjacent the outlet port, and the fluid flow is operable with an interior surface of the flow chamber to push the amount of the material through the outlet port.

13. The device of claim 12, further comprising a cap operable to permit insertion of the material in the flow chamber through the insertion port when the cap is disengaged from the body, and seal the insertion port when the cap is engaged with the body.

14. The device of claim 12, wherein the body has a handle portion.

15. The device of claim 12, further comprising a sheath extending distally from the outlet port, wherein the pusher is operable to push the amount of material into the sheath, and a distal end of the sheath includes at least one opening configured to distribute the amount of material.

16. The device of claim 15, wherein the at least one opening of the distal end of the sheath is moveable between an open position and a closed position.

17. The device of claim 12, wherein the pusher includes a stopper portion protruding from a radially outer surface of pusher, wherein the body includes an offshoot configured to allow the stopper portion to pass through the offshoot, wherein alignment of the stopper portion and the offshoot is configured to cause the resilient member to move from the compressed state to the expanded state.

18. A device comprising:

a body defining a flow chamber with an inlet port for receiving a fluid flow in the flow chamber;

an insertion port on the body for receiving a material in the flow chamber;

an outlet port on the body for exiting the material from the flow chamber;

a pusher operable to move the material out of the outlet port and biased toward or away from the outlet port by a resilient element, wherein the pusher is configured to move between a first position outside the outlet port and a second position at least partially within the outlet port when the resilient element moves from a compressed state to an expanded state, wherein a distalmost end of the pusher is configured to contact the material to move the material toward the outlet port; and

a sheath including a proximal end attached to the outlet port and a distal end including at least one sealed opening configured to be unsealed to exit the material.

19. The device of claim 18, wherein:

the fluid flow forms a suspension of the material in the flow chamber, an amount of the material collects in the flow chamber adjacent the outlet port, and the fluid flow is operable with an interior surface of the flow chamber to push the amount of the material through the outlet port and into the sheath; and

the at least one sealed opening of the distal end of the sheath includes a removable plug or cap.

20. The device of claim 18, wherein the pusher includes a stopper portion protruding from a radially outer surface of pusher, wherein the body includes an offshoot configured to allow the stopper portion to pass through the offshoot, wherein alignment of the stopper portion and the offshoot is configured to cause the resilient member to move from the compressed state to the expanded state.