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Bioactive components conjugated to substrates of microneedle arrays

  • US 10,441,768 B2
  • Filed: 03/18/2016
  • Issued: 10/15/2019
  • Est. Priority Date: 03/18/2015
  • Status: Active Grant
First Claim
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1. A dissolvable microneedle array for transdermal insertion into a patient comprising:

  • a substrate comprising a biocompatible material that forms base portion and a plurality of microneedles extending from the base portion; and

    one or more bioactive components conjugated to the biocompatible material,wherein the one or more bioactive components are cleavable in vivo by an enzyme to release the bioactive component from the biocompatible material, or the bioactive component retains function when conjugated to the biocompatible material.

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