Systems and methods for drug delivery, treatment, and monitoring
First Claim
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1. A treatment method, comprising:
- implanting a plurality of catheters in respective locations in a patient'"'"'s brain, each catheter having first and second discrete fluid channels therein;
attaching a skull anchor to which the plurality of catheters are coupled to the patient'"'"'s skull;
coupling a plurality of branch lines, each having a plurality of fluid lumens, to respective ones of the plurality of catheters, such that respective ones of the fluid lumens of each branch line are in fluid communication with respective ones of the first and second discrete fluid channels of the respective catheter to which that branch line is coupled, androuting the plurality of branch lines through a manifold to a trunk line, the trunk line having a plurality of independent fluid lumens extending therethrough, each of the plurality of independent fluid lumens of the trunk line being in fluid communication with the fluid lumens of a respective branch line and with a plurality of ports formed in a crosscutaneous access device, such that the number of independent fluid lumens of the trunk line entering the manifold is equal to the total number of the plurality of fluid lumens of the plurality of branch lines; and
delivering fluid through the access device to the trunk line, the plurality of branch lines, and the plurality of catheters into the patient'"'"'s brain.
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Abstract
Systems and methods for delivering a drug or other therapy over an extended period of time (e.g., several hours, days, weeks, months, years, and so forth) are disclosed herein, as are systems and methods for monitoring various parameters associated with the treatment of a patient. Systems and methods are also disclosed herein that generally involve CED devices with various features for reducing or preventing backflow.
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Citations
20 Claims
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1. A treatment method, comprising:
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implanting a plurality of catheters in respective locations in a patient'"'"'s brain, each catheter having first and second discrete fluid channels therein; attaching a skull anchor to which the plurality of catheters are coupled to the patient'"'"'s skull; coupling a plurality of branch lines, each having a plurality of fluid lumens, to respective ones of the plurality of catheters, such that respective ones of the fluid lumens of each branch line are in fluid communication with respective ones of the first and second discrete fluid channels of the respective catheter to which that branch line is coupled, and routing the plurality of branch lines through a manifold to a trunk line, the trunk line having a plurality of independent fluid lumens extending therethrough, each of the plurality of independent fluid lumens of the trunk line being in fluid communication with the fluid lumens of a respective branch line and with a plurality of ports formed in a crosscutaneous access device, such that the number of independent fluid lumens of the trunk line entering the manifold is equal to the total number of the plurality of fluid lumens of the plurality of branch lines; and delivering fluid through the access device to the trunk line, the plurality of branch lines, and the plurality of catheters into the patient'"'"'s brain. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification