Systems and methods for vagal nerve stimulation
First Claim
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1. A method of treating or preventing a disorder in a patient, the method comprising:
- positioning a contact surface of a device in contact with an outer skin surface of a neck of the patient, wherein the device comprises a housing and an energy source, wherein the energy source is located within the housing, wherein the contact surface is coupled to the energy source, and wherein the housing comprises an outer surface that includes the contact surface; and
applying, via the device, when the contact surface is in contact with the outer skin surface of the neck of the patient, one or more electrical impulses transcutaneously and non-invasively via the contact surface through the outer skin surface of the neck of the patient to a vagus nerve of the patient according to a treatment paradigm, wherein the energy source generates the one or more electrical impulses; and
wherein the treatment paradigm is based at least in part on an application of the electrical impulse as a single dose from two times to five times during the day.
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Abstract
Devices, systems and methods are disclosed for electrical stimulation of the vagus nerve to treat or prevent disorders in a patient. The methods comprise transmitting impulses of energy to the vagus nerve according to a treatment paradigm that includes single doses of 30 seconds to 5 minutes of continuous stimulation. The treatment paradigm further comprises one or more daily treatment sessions that each include one or more doses for prophylactic or acute treatment of the patient'"'"'s condition. Vagus nerve stimulation is used to modulate the release of inhibitory neurotransmitters in the brain, such as GABA, norepinephrine, and/or serotonin.
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Citations
22 Claims
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1. A method of treating or preventing a disorder in a patient, the method comprising:
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positioning a contact surface of a device in contact with an outer skin surface of a neck of the patient, wherein the device comprises a housing and an energy source, wherein the energy source is located within the housing, wherein the contact surface is coupled to the energy source, and wherein the housing comprises an outer surface that includes the contact surface; and applying, via the device, when the contact surface is in contact with the outer skin surface of the neck of the patient, one or more electrical impulses transcutaneously and non-invasively via the contact surface through the outer skin surface of the neck of the patient to a vagus nerve of the patient according to a treatment paradigm, wherein the energy source generates the one or more electrical impulses; and wherein the treatment paradigm is based at least in part on an application of the electrical impulse as a single dose from two times to five times during the day. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method of treating or preventing a disorder in a patient, the method comprising:
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positioning a contact surface of a device in contact with an outer skin surface of a neck of the patient, wherein the device comprises a housing and an energy source, wherein the energy source is located within the housing, wherein the contact surface is coupled to the energy source, and wherein the housing comprises an outer surface that includes the contact surface; and applying, via the device, when the contact surface is in contact with the outer skin surface of the neck of the patient, an electrical impulse transcutaneously and non-invasively via the contact surface through the outer skin surface of the neck of the patient to a vagus nerve of the patient according to a treatment paradigm, wherein the energy source generates the electrical impulse; and wherein the treatment paradigm is based at least in part on an application of the electrical impulse as a single dose every 4 to 5 hours during the day.
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Specification