Therapeutic window determination
First Claim
1. A method comprising:
- prior to implantation of a lead comprising a plurality of electrodes at a target implantation site within a patient, determining, by a processor, for each electrode of the plurality of electrodes and for each implantation site of a plurality of implantation sites, a therapeutic window of an electrical stimulation parameter based on an efficacy threshold value of the electrical stimulation parameter and an adverse-effects threshold value of the stimulation parameter, wherein the therapeutic window indicates at least one value of the electrical stimulation parameter associated with delivery of efficacious electrical stimulation via the electrode at the implantation site to the patient; and
selecting, by the processor, at least one implantation site of the plurality of implantation sites as the target implantation site based on therapeutic windows associated with the at least one implantation site.
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Accused Products
Abstract
A therapeutic window for at least one electrode of a medical system may be determined based on a volume of tissue expected to be activated (“VTA”) by electrical stimulation delivered by the at least one electrode. In some examples, a processor determines the therapeutic window for a particular electrode by at least determining an efficacy threshold based on the VTA expected to result from the delivery of electrical stimulation according to a set of electrical stimulation parameter values including the stimulation parameter at the efficacy threshold, and determining an adverse-effects threshold based on the VTA expected to result from the delivery of electrical stimulation according to a set of electrical stimulation parameter values including the stimulation parameter at the adverse-effects threshold.
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Citations
31 Claims
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1. A method comprising:
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prior to implantation of a lead comprising a plurality of electrodes at a target implantation site within a patient, determining, by a processor, for each electrode of the plurality of electrodes and for each implantation site of a plurality of implantation sites, a therapeutic window of an electrical stimulation parameter based on an efficacy threshold value of the electrical stimulation parameter and an adverse-effects threshold value of the stimulation parameter, wherein the therapeutic window indicates at least one value of the electrical stimulation parameter associated with delivery of efficacious electrical stimulation via the electrode at the implantation site to the patient; and selecting, by the processor, at least one implantation site of the plurality of implantation sites as the target implantation site based on therapeutic windows associated with the at least one implantation site. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A system comprising:
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a memory configured to store information identifying a plurality of implantation sites; and a processor configured to; determine, prior to implantation of a lead comprising a plurality of electrodes at a target site within a patient, for each electrode of the plurality of electrodes, and for each implantation site of the plurality of implantation sites, a therapeutic window of an electrical stimulation parameter based on an efficacy threshold value of the electrical stimulation parameter and an adverse-effects threshold value of the stimulation parameter, wherein the therapeutic window indicates at least one value of the electrical stimulation parameter associated with delivery of efficacious electrical stimulation via the electrode at the implantation site to the patient; and select at least one implantation site of the plurality of implantation sites as the target implantation site based on therapeutic windows associated with the at least one implantation site. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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26. A system comprising:
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means for determining, prior to implantation of a lead comprising a plurality of electrodes at a target implantation site within a patient, for each electrode of the plurality of electrodes, and for each implantation site of a plurality of implantation sites, a therapeutic window of an electrical stimulation parameter based on an efficacy threshold value of the electrical stimulation parameter and an adverse-effects threshold value of the stimulation parameter, wherein the therapeutic window indicates at least one value of the electrical stimulation parameter associated with delivery of efficacious electrical stimulation via the electrode at the implantation site to the patient; and means for selecting at least one implantation site of the plurality of implantation sites as the target implantation site based on therapeutic windows associated with the at least one implantation site. - View Dependent Claims (27, 28)
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29. A non-transitory computer-readable medium comprising instructions that, when executed by a processor, cause the processor to:
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determine, prior to implantation of a lead comprising a plurality of electrodes at a target site within a patient, for each electrode of the plurality of electrodes, and for each implantation site of a plurality of implantation sites, a therapeutic window of an electrical stimulation parameter based on an efficacy threshold value of the electrical stimulation parameter and an adverse-effects threshold value of the stimulation parameter, wherein the therapeutic window indicates at least one value of the electrical stimulation parameter associated with delivery of efficacious electrical stimulation via the electrode at the implantation site to the patient; and select at least one implantation site of the plurality of implantation sites as the target implantation site based on therapeutic windows associated with the at least one implantation site. - View Dependent Claims (30, 31)
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Specification