Skincare compositions

• US 10,441,822 B2
• Filed: 05/24/2018
• Issued: 10/15/2019
• Est. Priority Date: 07/17/2009
• Status: Active Grant

• Current Assignee: Reckitt Benckiser Incorporated (Reckitt Benckiser Group PLC)
• Original Assignee: Reckitt Benckiser Incorporated (Reckitt Benckiser Group PLC)
• Inventors: Buckley, Carolyn, Jackson, Stuart, Kilcullen, Neil, Pavis, Diane Marie
• Primary Examiner(s): Rosenthal, Andrew S
• Application Number:
  US15/988,595
• Publication Number:
  US 20180264292A1
• Time in Patent Office: 509 Days
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 2800/28 Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
• CPC Class Codes: A61K 31/045 Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
• CPC Class Codes: A61K 31/19 Carboxylic acids, e.g. valproic acid salicylic acid A61K31/60
• CPC Class Codes: A61K 31/4166 having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
• CPC Class Codes: A61K 31/60 Salicylic acid; Derivatives thereof
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61K 8/0208 Tissues; Wipes; Patches
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/365 Hydroxycarboxylic acids; Ketocarboxylic acids
• CPC Class Codes: A61K 8/368 with carboxyl groups directly bound to carbon atoms of aromatic rings
• CPC Class Codes: A61K 8/442 substituted by amido group(s)
• CPC Class Codes: A61K 8/4913 having five membered rings, e.g. pyrrolidone carboxylic acid
• CPC Class Codes: A61K 8/4946 Imidazoles or their condensed derivatives, e.g. benzimidazoles
• CPC Class Codes: A61K 8/602 Glycosides, e.g. rutin
• CPC Class Codes: A61K 8/63 Steroids; Derivatives thereof
• CPC Class Codes: A61K 8/675 Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde tocopheryl nicotinate A61K8/678
• CPC Class Codes: A61K 8/9789 Magnoliopsida [dicotyledons]
• CPC Class Codes: A61K 9/0014 Skin, i.e. galenical aspects of topical compositions non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00
• CPC Class Codes: A61P 17/10 : Anti-acne agents
• CPC Class Codes: A61P 29/00 : Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61P 31/00 : Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• CPC Class Codes: A61P 31/04 : Antibacterial agents
• CPC Class Codes: A61P 31/10 : Antimycotics
• CPC Class Codes: A61P 31/12 : Antivirals
• CPC Class Codes: A61Q 19/00 : Preparations for care of the skin
• CPC Class Codes: A61Q 19/008 : Preparations for oily skin

Abstract

This invention relates to skincare compositions, in particular compositions effective in the treatment of acne vulgaris, and to methods of treatment of the skin that involve the application of such compositions, wherein the compositions comprise salicylic acid or a salt thereof in combination with at least two actives selected from the group consisting of lactic acid or a salt thereof; glycyrrhizinic acid or a salt or a derivative thereof; bisabolol; cetylhydroxyproline palmitamide; allantoin; niacinamide; and Epilobium angustifolium extract.

Claims

1. A cosmetic method for improving the appearance of skin afflicted by acne lesions, said method comprising reducing the redness of said lesions by the topical application of a skincare composition consisting of:

salicylic acid or a salt thereof in a concentration of 2 wt %;

glycyrrhizinic acid or a salt thereof in a concentration of 0.05 wt %;

cetylhydroxyproline palmitamide in a concentration of 0.025 wt %;

lactic acid or a salt thereof in a concentration of 1.998 wt %;

bisabolol in a concentration of 0.025 wt %;

niacinamide in a concentration of 2 wt %;

a chelating agent in a concentration of 0.01 wt % to 0.1 wt %;

a gelling/thickening agent in a concentration of 0.1 wt % to 5 wt %;

an emulsifier in a concentration of 0.75 wt % to 12 wt %;

a mixed solvent system comprising water and a co-solvent wherein the co-solvent is present in a concentration of 0 wt % to about 5 wt % and the water forms the remainder of the composition;

an emollient in a concentration of 0 wt % to 8 wt %;

a humectant or moisturizer in a concentration of 0 wt % to 10 wt %;

a surfactant in a concentration of 0 wt % to about 38 wt %;

a preservative in a concentration of 0 wt % to 0.3 wt %;

an abrasive in a concentration of 0 wt % to 8.5 wt %;

an opacifying agent in a concentration of 0 wt % to 15 wt %;

a pH adjuster in a concentration of 0 wt % to 3 wt %;

a conditioning agent in a concentration of 0 wt % to 1.5 wt %;

a perfume in a concentration of 0 wt % to 0.35 wt %; and

a coloring in a concentration of 0 wt % to 0.00315 wt %,

wherein the composition has a viscosity of from about 10,000 mPa/s to about 200,000 mPa/s.

2. The method as claimed in claim 1, wherein the pH of the skincare composition is in the range from 3.5 to 6.0.

3. The method as claimed in claim 1, wherein the skincare composition has the form of one of an aqueous solution surfactant wash, an oily solution surfactant wash, a dispersion, an emulsion, or a gel.

4. The method as claimed in claim 3, wherein the skincare composition has the form of an emulsion comprising an oil-in-water emulsion.

5. The method as claimed in claim 3, wherein the skincare composition has the form of a gel comprising an aqueous gel.

6. An article comprising a fibrous substrate configured for topical application of the skincare composition according to claim 1.

7. The article as claimed in claim 6, the fibrous substrate selected from the group consisting of cellulose fibers, cotton fibers, and a mixture thereof.

8. A method for the treatment of acne comprising:

topically applying a skincare composition according to claim 1 to the skin of a patient.

9. The method as claimed in claim 8, which is a cosmetic method.

10. The method as claimed in claim 8, which is a therapeutic method.

11. The use of the composition according to claim 1 in a composition for the treatment of acne by topical application of the composition to the skin.

12. A method for reducing irritancy associated with the topical application of a skincare composition comprising topical application of a skincare composition according to claim 1.

13. A cosmetic method for improving the appearance of skin afflicted by acne lesions comprising reducing the redness of lesions by the topical application of a skincare composition according to claim 1.

14. The method as claimed in claim 3, wherein the skincare composition has the form of an emulsion selected from the group consisting of an oil-in-water emulsion, a water-in-oil emulsion, and a microemulsion.