Oxa spiro derivative, preparation method therefor, and applications thereof in medicines
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Abstract
The present invention relates to an oxa spiro derivative, a preparation method therefor, and applications thereof in medicines. Particularly, the present invention relates to an oxa spiro derivative represented by formula (I), a preparation method therefor, and a pharmaceutical composition comprising the derivative, applications thereof as an MOR receptor agonist, and applications in the preparation of drugs for treating and/or preventing pains and pains-related diseases. Substituent groups in the formula (I) are same as definitions in the specification.
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24 Claims
- 1. A compound of formula (I):
- 8. A compound selected from the group consisting of:
Specification