MRI with motion correction using navigators acquired using a dixon technique

• US 10,444,315 B2
• Filed: 02/04/2013
• Issued: 10/15/2019
• Est. Priority Date: 02/09/2012
• Status: Active Grant

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Beck, Gabriele Marianne, Nielsen, Tim, Simonetti, Arjan Willem, Herigault, Gwenael Henri, Visser, Mathijs
• Primary Examiner(s): Gillman, Amelie R
• Application Number:
  US14/377,213
• Publication Number:
  US 20150323637A1
• Time in Patent Office: 2,444 Days
• Field of Search: None
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: G01R 33/34 Constructional details, e.g. resonators , specially adapted to MR
• CPC Class Codes: G01R 33/385 using gradient magnetic field coils
• CPC Class Codes: G01R 33/4828 Resolving the MR signals of different chemical species, e.g. water-fat imaging
• CPC Class Codes: G01R 33/56509 due to motion, displacement or flow, e.g. gradient moment nulling G01R33/567 takes precedence
• CPC Class Codes: G01R 33/5673 Gating or triggering based on a physiological signal other than an MR signal, e.g. ECG gating or motion monitoring using optical systems for monitoring the motion of a fiducial marker
• CPC Class Codes: G01R 33/5676 Gating or triggering based on an MR signal, e.g. involving one or more navigator echoes for motion monitoring and correction

Abstract

At least a portion of a body (10) is placed in a main magnetic field Bo within the examination volume of a MR device. The portion of the body (10) is subject to an imaging sequence including one or more RF pulses and switched magnetic field gradients to acquire imaging signals. The portion of the body (10) is subject to a navigator sequence applied at least once before, during, or after the imaging sequence. The navigator sequence includes one or more RF pulses and switched magnetic field gradients controlled to acquire navigator signals with a single-point or multi-point Dixon technique. Translation and/or rotation and/or shear data reflecting motion of the body are derived from the navigator signals during the acquisition of the imaging signals. The translation and/or rotation and/or shear data are used for adapting the imaging sequence and/or for motion correction during reconstruction of an MR image.

Claims

1. A method of magnetic resonance (MR) imaging of at least a portion of a body placed in a main magnetic field B₀ within an examination volume of a MR device, the method comprising:

subjecting the portion of the body to an imaging sequence comprising one or more RF pulses and switched magnetic field gradients for acquiring imaging signals;

subjecting the portion of the body to a navigator sequence applied at least once before, during, or after the imaging sequence, the navigator sequence including one or more radio frequency (RF) pulses and switched magnetic field gradients controlled so that separate water navigator signals and fat navigator signals are acquired by means of a single-point or multi-point Dixon technique from a navigator volume of the navigator sequence when motion data indicative of motion occurring within the body exceeds a preselected threshold, the motion data being monitored by k-space navigators or one or more external sensors;

deriving translation and/or rotation and/or shear data from the water navigator signals and the fat navigator signals, wherein the translation and/or rotation and/or shear data reflect the motion occurring within the body;

reconstructing MR images from the imaging signals,

wherein the translation and/or rotation and/or shear data are used for adapting the imaging sequence and/or for motion correction during reconstruction of the MR images.

2. The method of claim 1, wherein the imaging sequence is a single-point or multi-point Dixon technique which generates separate water imaging signals and fat imaging signals, and wherein reconstructing the MR images includes reconstructing the water imaging signals into a water image and reconstructing the fat imaging signals into a fat image.

3. The method of claim 1, further including:

generating a B₀ map indicating spatial and/or temporal variations of the main magnetic field using the multi-point Dixon technique; and

adjusting shim settings of the MR device during acquisition of the imaging signals on the basis of the B₀ map.

4. The method of claim 1, further including:

extracting a B₀ map indicating spatial and/or temporal variations of the main magnetic field in regions containing predominantly water using the multi-point Dixon technique; and

from a homogeneous B₀ region containing predominantly water, determining an actual MR resonance frequency of water.

5. The method of claim 4, further including:

with the B₀ map, correcting for the spatial variations of the main magnetic field during the reconstructing of the MR images.

6. A magnetic resonance (MR) device comprising at least one main magnet coil configured to generate a main magnetic field B₀ within an examination volume, a plurality of gradient coils configured to generate switched magnetic field gradients in different spatial directions within the examination volume, at least one radio frequency (RF) coil configured to generate RF pulses within the examination volume and to receive MR signals from a body of a patient positioned in the examination volume, a reconstruction processor configured to reconstruct MR images from the received MR signals, and a control processor configured to:

control the gradient coils and the at least one RF coil to subject a portion of the body to an imaging sequence comprising one or more RF pulses and switched magnetic field gradients for acquiring imaging signals;

control the gradient coils and the at least one RF coil to subject the portion of the body to a navigator sequence applied at least once before, during, or after the imaging sequence, the navigator sequence comprising one or more RF pulses and switched magnetic field gradients used to acquire Dixon water navigator signals and Dixon fat navigator signals by a single-point or multi-point Dixon technique and to acquire non-Dixon k-space navigator signals when motion data indicative of motion occurring within the body exceeds a preselected threshold, the motion data being monitored by k-space navigators or one or more external sensors;

derive translation and/or rotation and/or shear data from the Dixon water and fat navigator signals, wherein the translation and/or rotation and/or shear data reflect the motion occurring within the body;

reconstruct MR images from the imaging signals; and

use the translation and/or rotation and/or shear data for adapting the imaging sequence and/or for motion correction during the reconstruction of the MR images.

7. A non-transitory computer-readable medium carrying a computer program which controls one or more computers of a magnetic resonance (MR) device to control the MR device to:

generate an imaging sequence comprising one or more RF pulses and switched magnetic field gradients for acquiring imaging signals;

generate a Dixon navigator sequence and a non-Dixon k-space navigator sequence in an interleaved manner, the navigator sequences being applied at least once before, during, or after the imaging sequence;

derive translation and/or rotation and/or shear data from water navigator signals and fat navigator signals acquired by applying the Dixon navigator sequence, wherein the translation and/or rotation and/or shear data reflect motion occurring within a body;

wherein the water navigator signals and the fat navigator signals are acquired when motion data indicative of the motion occurring within the body exceeds a threshold, the motion data being monitored by non-Dixon k-space navigator signals acquired by applying the non-Dixon k-space navigator sequence or by one or more external sensors;

reconstruct a MR image from the imaging signals; and

use the translation and/or rotation and/or shear data for adapting the imaging sequence and/or for motion correction during reconstruction of the MR image.

8. The non-transitory computer-readable medium of claim 7, wherein the computer program controls the one or more computers of a magnetic resonance (MR) device to control the MR device to:

generate a main field homogeneity map from the Dixon water and fat navigator signals; and

from regions containing predominantly water and a homogeneous main magnetic field, determine an actual MR frequency of water.

9. A magnetic resonance (MR) device comprising at least one main magnet coil configured to generate a main magnetic field B₀ within an examination volume, a plurality of gradient coils configured to generate switched magnetic field gradients in different spatial directions within the examination volume, at least one radio frequency (RF) coil configured to generate RF pulses within the examination volume and to receive MR signals from a body of a patient positioned in the examination volume, a reconstruction processor configured to reconstruct MR images from the received MR signals, and a control processor configured to:

control the gradient coils and the at least one RF coil to subject a portion of the body to an imaging sequence comprising one or more RF pulses and switched magnetic field gradients for acquiring imaging signals;

control the gradient coils and the at least one RF coil to generate non-Dixon k-space navigator sequences and Dixon navigator sequences, at least one of the non-Dixon and Dixon navigator sequences being generated at least once before, during, or after the imaging sequence, each Dixon navigator sequence comprising one or more RF pulses and switched magnetic field gradients controlled to acquire Dixon water navigator signals and Dixon fat navigator signals by a single-point or multi-point Dixon technique when motion data indicative of motion occurring within the body exceeds a preselected threshold, the motion data being monitored by k-space navigators or one or more external sensors; and

derive translation and/or rotation and/or shear data from the Dixon water and fat navigator signals, wherein the translation and/or rotation and/or shear data reflect the motion occurring within the body.

10. The magnetic resonance device of claim 9, wherein the control processor is further configured to:

correct spatial and/or temporal variations of the main magnetic field in regions of the body portion that are primarily water based on the Dixon water navigator signals;

correct spatial and/or temporal variations of the main magnetic field in regions of the body portion that are primarily fat based on the Dixon fat navigator signals.

11. A method of magnetic resonance (MR) imaging of at least a portion of a body placed in a main magnetic field B₀ within an examination volume of an MR device, the method comprising:

subjecting the portion of the body to an imaging sequence comprising one or more RF pulses and switched magnetic field gradients for acquiring imaging signals;

subjecting the portion of the body to a navigator sequence applied at least once before, during, or after the imaging sequence, the navigator sequence comprising one or more RF pulses and switched magnetic field gradients controlled in such a manner that non-Dixon k-space navigator signals and Dixon navigator signals are acquired from a navigator volume, the Dixon navigator signals being acquired using a single-point or multi-point Dixon technique when motion data indicative of motion occurring within the body exceeds a preselected threshold, the motion data being monitored by k-space navigators or one or more external sensors, wherein the Dixon navigator signals include separate water navigator signals and fat navigator signals;

deriving translation and/or rotation and/or shear data from the water navigator signals and fat navigator signals of the Dixon navigator signals, wherein the translation and/or rotation and/or shear data reflect motion occurring within the body;

reconstructing MR images from the imaging signals,

wherein the translation and/or rotation and/or shear data are used for adapting the imaging sequence and/or for motion correction during the reconstruction of the MR images.