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Systems and methods for medical data processing and analysis

  • US 10,446,264 B2
  • Filed: 01/30/2014
  • Issued: 10/15/2019
  • Est. Priority Date: 01/30/2013
  • Status: Active Grant
First Claim
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1. A method for treating a patient following a surgical procedure, the method comprising:

  • inputting acute phase response (APR) biomarker data defining a level of an acute phase response (APR) biomarker in said patient at a succession of biomarker measurement times following said medical procedure, said APR biomarker data defining a biomarker time course representing an evolution over time of said acute phase response;

    processing said APR biomarker data to determine a derivative with respect to time of said time course from said APR biomarker data to provide APR time series data, wherein said processing of said APR biomarker data to determine said derivative with respect to time of said time course further comprises correcting for a clearance rate of said biomarker in said patient;

    identifying one or both of a maximum and a minimum in said APR time series data;

    determining a value for an alert state variable responsive to said APR time series data; and

    if the alert state variable has a first value then treating the patient for infection.

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