System and method for bioelectric localization and navigation of interventional medical devices

• US 10,448,860 B2
• Filed: 03/13/2013
• Issued: 10/22/2019
• Est. Priority Date: 03/13/2013
• Status: Active Grant

• Current Assignee: Johns Hopkins University
• Original Assignee: Johns Hopkins University
• Inventors: Navab, Nassir, Cowan, Noah, Fuerst, Bernhard, Fortune, Eric S.
• Primary Examiner(s): Henson, Devin B
• Assistant Examiner(s): Nguyen, Huong Q
• Application Number:
  US13/798,637
• Publication Number:
  US 20140276190A1
• Time in Patent Office: 2,414 Days
• CPC Class Codes: A61B 2034/2053 Tracking an applied voltage gradient
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 5/066 Superposing sensor position on an image of the patient, e.g. obtained by ultrasound or x-ray imaging
• CPC Class Codes: A61B 5/068 using impedance sensors

Abstract

A system and method for tracking a position of an interventional medical device configured to be deployed into a subject during a medical procedure. An anatomical dataset of the subject is acquired while at least one electrical sensor is disposed along the interventional medical device. A feedback signal is generated from the electrical sensor and is processed and analyzed to identify positional information of the interventional medical device. A position of the interventional medical device with respect to the anatomical dataset is identified and the position of the interventional medical device with respect to the anatomical dataset is shown on a display.

Claims

1. A system for tracking a position of an interventional medical device configured to be deployed into a subject during a medical procedure, the system comprising:

the interventional medical device configured to be deployed into the subject during the medical procedure, wherein the interventional medical device is configured to be displaced within the subject during the medical procedure;

wherein an electrical source is disposed on or in the interventional medical device, and

wherein the electrical source is configured to emit an electrical signal to a region of a body away from the interventional medical device being displaced within the subject during the medical procedure;

wherein one or more electrical sensors is disposed on or in the interventional medical device, and

wherein the one or more electrical sensors is configured to receive response electrical signals from the region of the body in response to the emitted electrical signal from the electrical source when the interventional medical device is displaced within the subject during the medical procedure to generate a feedback signal based on the received response electrical signals;

a non-transitive memory configured to store therein an anatomical dataset including anatomical information that is specific to an anatomy of the subject;

a processor configured to access the anatomical dataset from the non-transitive memory and communicatively coupled to the one or more electrical sensors to receive and analyze the feedback signal, based at least on the anatomical information that is specific to the anatomy of the subject, to identify positional information of the interventional medical device relative to the anatomical dataset and the anatomy of the subject during the displacement of the interventional medical device within the subject, wherein the positional information comprises a first position of the interventional medical device and a second position of the interventional medical device different from the first position and indicative of the displacement of the interventional medical device; and

a display coupled to the processor to communicate at least the first position and the second position of the interventional medical device with respect to the anatomical dataset.

2. The system as recited in claim 1 wherein the feedback signal indicates bio-electric signals received by the one or more sensors.

3. The system as recited in claim 1 wherein the processor is further configured to determine at least one of a velocity and a positional change of the interventional medical device to identify the positional information of the interventional medical device.

4. The system as recited in claim 3, wherein the one or more electrical sensors comprises a plurality of electrical sensors disposed on or in the interventional medical device at a distal position to a proximal position and are configured to generate a plurality of feedback signals, wherein the processor is further configured to determine time delays reflected in the feedback signals in order to determine the velocity of the interventional medical device.

5. The system as recited in claim 1 wherein the interventional medical device is at least one of a catheter, guidewire, laparoscope or endoscope.

6. The system as recited in claim 1 wherein the anatomical dataset includes at least one of a prior fluoroscopy, computed tomography (CT), and magnetic resonance imaging (MRI) dataset.

7. The system as recited in claim 1 wherein the feedback signal is configured to create an electrical image of a local volume surrounding the interventional medical device.

8. A method for tracking a placement of an interventional medical device deployed into a subject, the method comprising the steps of:

a) acquiring an anatomical dataset of that is specific to an anatomy of the subject;

b) providing an interventional medical device having one or more electrical sensors disposed on or in the interventional medical device;

c) positioning the interventional medical device within the subject during a medical procedure, wherein the interventional medical device is configured to be displaced within the subject during the medical procedure, wherein an electrical source is disposed on or in the interventional medical device and is configured to emit an electrical signal to a region of a body of the subject away from the interventional medical device being displaced within the subject during the medical procedure, and

wherein the one or more electrical sensors disposed on or in the interventional medical device and is configured to receive a response electrical signal from the region of the body in response to the emitted electrical signal from the electrical source to generate a feedback signal based at least on the received response electrical signal;

d) processing the feedback signal generated from the one or more electrical sensors;

e) analyzing, based on the anatomical data set, the feedback signal to identify positional information of the interventional medical device relative to the anatomical data set and the anatomy of the subject during the displacement of the interventional medical device within the subject, wherein the positional information comprises a first position of the interventional medical device and a second position of the interventional medical device different from the first position and indicative of the displacement of the interventional medical device; and

f) displaying at least the first position and the second position of the interventional medical device with respect to the anatomical dataset.

9. The method as recited in claim 8 wherein the anatomical dataset is a previously stored dataset acquired from a non-transitive memory.

10. The method as recited in claim 8 wherein feedback signal indicates bio-electric signals received by the one or more electrical sensors.

11. The method as recited in claim 8 further comprising processing at least one of a velocity and a positional change of the interventional medical device to identify the positional information of the interventional medical device.

12. The method as recited in claim 11, wherein the one or more electrical sensors comprise a plurality of electrical sensors generating a plurality of feedback signals, the plurality of electrical signals disposed on or in the interventional medical device at a distal position to a proximal position, and determining time delays reflected in the first and second feedback signals in order to determine the velocity of the interventional medical device.

13. The method as recited in claim 8 wherein the anatomical dataset includes at least one of a prior fluoroscopy, computed tomography (CT), and magnetic resonance imaging (MRI) dataset.

14. The method as recited in claim 8 wherein the interventional medical device is at least one of a catheter, guidewire, laparoscope or endoscope.