Advanced analyte sensor calibration and error detection
First Claim
1. A method for calibrating sensor data generated by a continuous analyte sensor, comprising:
- generating sensor data using a continuous analyte sensor;
iteratively determining, with an electronic device, a sensitivity value of the continuous analyte sensor by applying a priori information comprising a sensitivity profile, wherein the sensitivity profile is a function, wherein time is an input of the function, wherein the sensitivity profiled is generated based on calibration-check information of the continuous analyte sensor;
iteratively determining a baseline estimation modeled after in vivo or in vitro measurements of baseline; and
calibrating the sensor data based at least in part on the determined sensitivity value and based at least in part on the baseline estimation.
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Abstract
Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.
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Citations
13 Claims
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1. A method for calibrating sensor data generated by a continuous analyte sensor, comprising:
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generating sensor data using a continuous analyte sensor; iteratively determining, with an electronic device, a sensitivity value of the continuous analyte sensor by applying a priori information comprising a sensitivity profile, wherein the sensitivity profile is a function, wherein time is an input of the function, wherein the sensitivity profiled is generated based on calibration-check information of the continuous analyte sensor; iteratively determining a baseline estimation modeled after in vivo or in vitro measurements of baseline; and calibrating the sensor data based at least in part on the determined sensitivity value and based at least in part on the baseline estimation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification