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System and method for temporal and spatial detection of seizure onset

  • US 10,448,878 B2
  • Filed: 04/17/2017
  • Issued: 10/22/2019
  • Est. Priority Date: 10/07/2016
  • Status: Active Grant
First Claim
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1. A system for temporal and spatial detection of seizure onset comprising:

  • an electrode unit for positioning inside or on an outer surface of a brain portion, said electrode unit including at least one electrode collection sub-unit, each electrode collection sub-unit containing a plurality of electrodes for corresponding a plurality of detection points, the quantity of the electrodes being defined as M, the quantity of detection points being defined as M as well; and

    a processing unit being electrically connected to said electrode unit and including an original electrical voltage collecting module, an electrical voltage difference processing module, a frequency separating processing module, an electrical voltage wave envelope processing module, and a co-relation processing module;

    said original electrical voltage collecting module being configured to detect said detection points via said electrodes for a working time so as to obtain a plurality of electric voltage variation wave information;

    wherein the quantity of M being a positive integer and being greater than or equal to 4;

    said electrical voltage difference processing module which connects with said original electrical voltage collecting module being configured to get all the electric voltage variation wave information having the quantity of M and then to compute a subtract operation between two neighboring electrical voltage variation wave information respectively, wherein a plurality of electrical voltage difference waves having the quantity of M−

    1 are obtained;

    said frequency separating processing module which connects with said electrical voltage difference processing module being configured to conduct a frequency separating process for every electrical voltage difference wave, so that each electrical voltage difference wave being filtered out and separated into a first band wave signal and a second band wave signal, in which said first band wave signal having a frequency range of 80-250 Hz, said second band wave signal having a frequency range of 250-600 Hz;

    said electrical voltage wave envelope processing module which connects with said frequency separating processing module adapted to get a plurality of wave envelope lines of said first band wave signals so as to obtain several first band wave envelope signals and to get a plurality of wave envelope lines of said second band wave signals so as to obtain several second band wave envelope signals; and

    said co-relation processing module which connects with said electrical voltage wave envelope processing module being configured to conduct a co-relation processing during a time segment of said working time and said co-relation processing being performed between respective first band wave envelope signals and second band wave envelope signals, so that a co-relation table in a two-dimensional (M−

    1) by (M−

    1) forms, so as to determine a position where an intracranial brain wave abnormality occurs.

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