Systems, methods, and devices for assessing microbiota of skin
First Claim
1. A system for assessing microbiota of skin comprising:
- an image-capture device including circuitry to capture at least one image of an inner surface of a skin-covering material, wherein the skin-covering material includes an inner surface and an outer surface, the inner surface of the skin-covering material substantially conforming in shape to a topography of a skin surface of an individual and including attached thereto a plurality of signal-generating complexes, one or more of the plurality of signal-generating complexes configured to emit one or more signals in response to at least one type of microbe, and wherein the image includes one or more signals emitted from one or more of the plurality of signal-generating complexes in response to the at least one type of microbe and to transform the captured at least one image into a digital output including information associated with at least one property and a spatial distribution of the imaged one or more signals; and
a computing device including a processor, the computing device operably coupled to the image-capture device and including circuitry configured toreceive the digital output from the image-capture device including the information associated with the at least one property and the spatial distribution of the imaged one or more signals emitted from the one or more of the plurality of signal-generating complexes in response to the at least one type of microbe;
compare the properties of the imaged one or more signals emitted from the one or more of the plurality of signal-generating complexes in response to the at least one type of microbe with a database of emitted signals of reference signal-generating complexes; and
generate a digital spatial profile of the at least one type of microbe based on the spatial distribution of the imaged one or more signals emitted from the one or more of the plurality of signal-generating complexes in response to the at least one type of microbe.
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Abstract
Devices, systems, and methods for assessing microbiota of skin are described, including: a skin-covering material including an inner surface and an outer surface, the inner surface substantially conforming to a topography of a skin surface of an individual and including a plurality of signal-generating complexes, one or more of the plurality of signal-generating complexes configured to emit one or more signals in response to at least one type of microbe; an image capture device to capture an image of the inner surface of the skin-covering material, the image including one or more signals emitted from the plurality of signal-generating complexes, and to transform the image into a digital output; and a computing device including circuitry configured to receive the digital output, compare the properties of the imaged one or more signals with a database of reference signal-generating complexes, and generate a digital spatial profile of microbes on the skin-covering material.
90 Citations
20 Claims
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1. A system for assessing microbiota of skin comprising:
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an image-capture device including circuitry to capture at least one image of an inner surface of a skin-covering material, wherein the skin-covering material includes an inner surface and an outer surface, the inner surface of the skin-covering material substantially conforming in shape to a topography of a skin surface of an individual and including attached thereto a plurality of signal-generating complexes, one or more of the plurality of signal-generating complexes configured to emit one or more signals in response to at least one type of microbe, and wherein the image includes one or more signals emitted from one or more of the plurality of signal-generating complexes in response to the at least one type of microbe and to transform the captured at least one image into a digital output including information associated with at least one property and a spatial distribution of the imaged one or more signals; and a computing device including a processor, the computing device operably coupled to the image-capture device and including circuitry configured to receive the digital output from the image-capture device including the information associated with the at least one property and the spatial distribution of the imaged one or more signals emitted from the one or more of the plurality of signal-generating complexes in response to the at least one type of microbe; compare the properties of the imaged one or more signals emitted from the one or more of the plurality of signal-generating complexes in response to the at least one type of microbe with a database of emitted signals of reference signal-generating complexes; and generate a digital spatial profile of the at least one type of microbe based on the spatial distribution of the imaged one or more signals emitted from the one or more of the plurality of signal-generating complexes in response to the at least one type of microbe. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method comprising:
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capturing at least one image of an inner surface of a skin-covering material with an image-capture device, wherein the skin-covering material has been removed from a skin surface of an individual, the inner surface of the skin-covering material substantially conforming in shape to a topography of the skin surface of the individual and including attached thereto a plurality of signal-generating complexes, one or more of the plurality of signal-generating complexes configured to emit one or more signals in response to at least one type of microbe, and wherein the at least one image includes one or more signals emitted from one or more of the plurality of signal-generating complexes in response to the at least one type of microbe and transforming the captured at least one image into a digital output including information associated with at least one property and a spatial distribution of the imaged one or more signals; receiving the digital output from the image-capture device, the digital output including information associated with at the least one property and the spatial distribution of the imaged one or more signals emitted from the one or more of the plurality of signal-generating complexes in response to the at least one type of microbe; identifying the at least one type of microbe by comparing the information associated with the at least one property of the imaged one or more signals emitted from the one or more of the plurality of signal-generating complexes with a database of signal properties of reference signal-generating complexes; generating a digital spatial profile of the at least one type of microbe based on the spatial distribution of the imaged one or more signals emitted from the one or more of the plurality of signal-generating complexes; and reporting to a user an identification and the digital spatial profile of the identified at least one type of microbe. - View Dependent Claims (19, 20)
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Specification