Method for optimizing a brachytherapy radiation treatment plan

• US 10,449,386 B2
• Filed: 09/27/2013
• Issued: 10/22/2019
• Est. Priority Date: 03/14/2013
• Status: Active Grant

• Current Assignee: Siemens Healthineers International AG (Siemens AG)
• Original Assignee: Varian Medical Systems International AG (Siemens AG)
• Inventors: Bask, Joni, Taiminen, Toni
• Primary Examiner(s): Dorna, Carrie R
• Application Number:
  US14/040,186
• Publication Number:
  US 20140275713A1
• Time in Patent Office: 2,216 Days
• CPC Class Codes: A61N 5/1001 using radiation sources introduced into or applied onto the body; brachytherapy
• CPC Class Codes: A61N 5/1031 using a specific method of dose optimization
• CPC Class Codes: A61N 5/1038 taking into account previously administered plans applied to the same patient, i.e. adaptive radiotherapy
• CPC Class Codes: A61N 5/1047 with movement of the radiation head during application of radiation, e.g. for intensity modulated arc therapy or IMAT
• CPC Class Codes: A61N 5/1048 Monitoring, verifying, controlling systems and methods
• CPC Class Codes: A61N 5/1064 for adjusting radiation treatment in response to monitoring

Abstract

A control circuit optimizes a brachytherapy radiation treatment plan for a patient target volume by defining a radiation-control structure that conformally surrounds the patient target volume and then automatically removes part, but not all, of the radiation-control structure to control consideration of radiation sources that are not disposed within the patient target volume. By one approach the control circuit selectively removes parts of the radiation-control structure as a function of the geometry as corresponds to placement of one or more of the radiation sources. For many application settings it serves well for the radiation-control structure to represent a radiation-avoidance area.

Claims

1. A method for optimizing a brachytherapy radiation treatment plan for a patient target volume comprising:

by a control circuit;

defining a radiation-control structure that conformally surrounds the patient target volume and wherein the radiation-control structure is a radiation-avoidance area and hence an area that a brachytherapy radiation treatment plan optimizer should avoid as much as possible and wherein the radiation-control structure has a user-chosen thickness;

automatically removing part, but not all, of the radiation-control structure to thereby leave only a remaining part of the radiation-control structure to control consideration of radiation source locations that are not disposed within the patient target volume; and

optimizing the brachytherapy radiation treatment plan for the patient target volume with respect to at least one of the radiation source locations that is not disposed within the patient target volume as a function, at least in part, of the remaining part of the radiation-control structure; and

placing radiation sources in a patient with respect to the patient target volume in accordance with the optimized brachytherapy radiation treatment plan.

2. The method of claim 1 wherein the brachytherapy radiation treatment plan presumes pre-placement of a plurality of radiation source locations with respect to the patient target volume.

3. The method of claim 2 wherein automatically removing part, but not all, of the radiation-control structure comprises automatically removing part, but not all, of the radiation-control structure as a function, at least in part, of geometry as corresponds to placement of at least some of the plurality of radiation sources.

4. The method of claim 1 wherein the radiation-avoidance area presents non-uniform radiation-avoidance preferences.

5. The method of claim 4 wherein the non-uniform radiation-avoidance preferences comprise a gradient of radiation-avoidance preferences.

6. The method of claim 1 wherein controlling consideration of the radiation source locations that are not disposed within the patient target volume comprises controlling consideration of the radiation source locations that are not disposed within the patient target volume when optimizing the brachytherapy radiation treatment plan for the patient target volume.

7. The method of claim 6 wherein optimizing the brachytherapy radiation treatment plan for the patient target volume comprises optimizing the brachytherapy radiation treatment plan for the patient target volume with respect to at least one of:

a number of radiation-source applicators;

placement of at least one radiation-source applicators;

placement of at least one of the radiation source locations;

a radiation-source strength;

dwell time for radiation source irradiation exposure.

8. A method comprising:

by a control circuit configured to optimize a brachytherapy radiation treatment plan for a patient target volume;

defining a radiation-control structure that conformally surrounds the patient target volume and wherein the radiation-control structure is a radiation-avoidance area and hence an area that a brachytherapy radiation treatment plan optimizer should avoid as much as possible;

automatically removing part, but not all, of the radiation-control structure to thereby leave only a remaining part of the radiation-control structure to control consideration of radiation source locations that are not disposed within the patient target volume; and

optimizing the brachytherapy radiation treatment plan for the patient target volume with respect to at least one of the radiation source locations that is not disposed within the patient target volume as a function, at least in part, of the remaining part of the radiation-control structure; and

placing radiation sources in a patient with respect to the patient target volume in accordance with the optimized brachytherapy radiation treatment plan.