×

Compounds for inducing anti-tumor immunity and methods thereof

  • US 10,450,566 B2
  • Filed: 03/14/2018
  • Issued: 10/22/2019
  • Est. Priority Date: 09/25/2013
  • Status: Active Grant
First Claim
Patent Images

1. A method for treatment of cancer in a subject in need thereof, the method comprising:

  • contacting antigen presenting cells (APCs) with a direct inhibitor of IRE-1α

    , wherein the direct inhibitor of IRE1α

    is present in an amount sufficient to increase antigen presentation in the APCs; and

    administering the APCs contacted with the direct inhibitor of IRE-1α

    , to a subject, wherein the subject has a solid cancer, and wherein the solid cancer comprises an epithelial cancer, a germ cell cancer, or a stromal tumor.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×