Convection current freeze drying apparatus and method of operating the same

• US 10,451,346 B1
• Filed: 03/31/2019
• Issued: 10/22/2019
• Est. Priority Date: 03/31/2019
• Status: Active Grant

• Current Assignee: Vinamit Jsc
• Original Assignee: Vinamit USA LLC
• Inventors: Nguyen, Vien Lam
• Primary Examiner(s): Gravini, Stephen M
• Application Number:
  US16/371,097
• Time in Patent Office: 205 Days
• Field of Search: 34296
• CPC Class Codes: F26B 21/06 Controlling, e.g. regulating, parameters of gas supply F26B21/14 takes precedence; control in general G05
• CPC Class Codes: F26B 5/044 for drying materials in a batch operation in an enclosure having a plurality of shelves which may be heated F26B5/045 takes precedence
• CPC Class Codes: F26B 5/06 the process involving freezing
• CPC Class Codes: F26B 5/065 the product to be freeze-dried being sprayed, dispersed or pulverised
• CPC Class Codes: F26B 9/066 the products to be dried being disposed on one or more containers, which may have at least partly gas-previous walls, e.g. trays or shelves in a stack F26B9/003 takes precedence; in combination with duct systems F26B21/00

Abstract

A convection current vacuum freeze drying apparatus is disclosed which includes a dryer chamber unit comprising a plurality of trays for depositing products to be freeze dried; a convection current condenser unit, mechanically connected to the dryer chamber unit, comprising a plurality of first elongate heat exchange tubes each having fins arranged around an outer circumference of the first elongate heat exchange tube; a refrigerator unit mechanically connected to the convection current condenser unit, operable to provide cold temperature to the plurality of elongate heat exchange tubes; a cooling tower unit mechanically connected to the convection current condenser unit; a primary vacuum pump unit, mechanically connected to the convection current condenser unit and the cooling tower unit, operable to provide a vacuum pressure to said convection current condenser unit; and a heater unit mechanically connected to provide a heat energy to both the dryer chamber unit and the convection current condenser unit.

Claims

1. A convection current vacuum freeze drying apparatus, comprising:

a dryer chamber unit comprising a plurality of trays for depositing products to be freeze dried;

a convection current condenser unit, mechanically connected to said dryer chamber unit, comprising a plurality of first elongate heat exchange tubes, each of said plurality of first elongate heat exchange tubes having fins arranged around an outer circumference of each of said plurality of first elongate heat exchange tubes, wherein said plurality of first elongate heat exchange tubes substantially fill the internal volume of said convection current condenser unit;

a refrigerator unit mechanically connected to said convection current condenser unit, operable to provide a cold refrigerant gas to said plurality of elongate heat exchange tubes;

a cooling tower unit mechanically connected to said convection current condenser unit;

a primary vacuum pump unit, mechanically connected to said convection current condenser unit and said cooling tower unit, operable to provide a vacuum pressure to said convection current condenser unit; and

a heater unit mechanically connected to provide a heat energy to both said dryer chamber unit and said convection current condenser unit.

2. The convection current vacuum freeze drying apparatus of claim 1 further comprising:

a controller unit; and

a database electrically coupled to communicate with said controller unit, wherein said controller unit is electrically coupled to control and receive sensed operational settings from said dryer chamber unit, said convection current condenser unit, said refrigerator unit, said cooling tower unit, said principle vacuum pump unit, and said heater unit, wherein said database is configured to store predetermined operational settings and wherein said controller unit is operable to compare said sensed operational settings and said predetermined operational settings.

3. The convection current vacuum freeze drying apparatus of claim 1 further comprising an auxiliary vacuum unit mechanically connected to said convection current condenser unit and said controller unit.

4. The convection current vacuum freeze drying apparatus of claim 1 further comprising a plurality of sensors, wherein said plurality of sensors further comprise thermometers, pressure sensors, timing devices, pumps, valves, and flow meters.

5. The convection current vacuum freeze drying apparatus of claim 1 wherein said controller unit further comprises a desktop computer, a laptop computer, a programmable logic controller (PLC), and a supervisory control and data acquisition (SCADA).

6. The convection current vacuum freeze drying apparatus of claim 4 wherein said apparatus is connected to a network and said controller unit communicates with said plurality of sensors via a first communication channel and wherein said controller unit performs a convection current freeze drying process via a second communication channel.

7. The convection current vacuum freeze drying apparatus of claim 1 wherein said plurality of first elongate heat exchange tubes forms a three-dimensional N×

M×

L array of first elongate heat exchange tubes, where N is a number of said plurality of first elongate heat exchange tubes arranged in a first direction and M is a number of said plurality of first elongate heat exchange tubes arranged in a second direction, and each of said plurality of first elongate heat exchange tubes has is straight with a length L extended in a third direction, wherein said L, M, and N are non-zero integers.

8. The convection current vacuum freeze drying apparatus of claim 7 wherein each column of said three-dimensional N×

M×

L array comprises a vertical zig-zag heat exchange tubes formed by said N of said plurality of first elongate heat exchange tubes.

9. The convection current vacuum freeze drying apparatus of claim 8 wherein each of said vertical zig-zag heat exchange tubes are arranged in a horizontally staggered manner and strung together by first curved connecting tubes which alternatively connect two proximate ends and two distal ends of two adjacent said plurality of first elongate heat exchange tubes so that said vertical zig-zag elongate tubes are configured to receive a cold refrigerant gas from said refrigerator unit via said vertical zig-zag tubes located at the bottom row of said N×

M×

L matrix and to output a warm refrigerant liquid back to said refrigerator unit via said vertical zig-zag tubes located at the bottom row of said N×

M×

L matrix.

10. The convection current vacuum freeze drying apparatus of claim 9 wherein said convection current condenser unit further comprises a three-dimensional M×

N×

L array of a plurality of second elongate tubes without fins, wherein said three-dimensional M×

N×

L array of said plurality of first elongate tubes is fixed on top of said M×

N×

L array of said plurality of second elongate tubes without fins.

11. The convection current vacuum freeze drying apparatus of claim 10 wherein each column of said three-dimensional N×

M×

L array of a plurality of second elongate tubes without fins comprises N of said plurality of second elongate heat exchange tubes without fins arranged in a horizontally staggered manner and strung together by second curved connecting tubes which alternatively connect two consecutive proximate ends and two consecutive distal ends of two adjacent of said plurality of second elongate heat exchange tubes without fins so as to form second vertical zig-zag elongate tubes configured to receive a cold refrigerant gas from said refrigerator unit via said second vertical zig-zag elongate tubes located at the bottom row of said N×

M×

L array and output a warm refrigerant liquid back to said refrigerator unit via said second vertical zig-zag elongate tubes located at the top row of said N×

M×

L array of said three-dimensional N×

M array.

12. The convection current vacuum freeze drying apparatus of claim 11 wherein M equals to 8 and N equals to 12 and wherein each of said plurality of first elongate heat exchange tubes has a length of 30 mm.

13. The convection current vacuum freeze drying apparatus of claim 12 wherein said cylindrical tube is made of an aluminum alloy and has a circumference of 89.9 mm, a radius of 35 mm and a thickness of 3.4 mm and wherein said rectangular fin has a width of 30 mm and a length of 30 mm and a thickness of 4 mm.

14. The convection current vacuum freeze drying apparatus of claim 13 wherein each of said plurality of first elongate heat exchange tubes further comprises a cylindrical tube and five rectangular fins arranged around an outer circumference of said cylindrical tube, wherein one of said five rectangular fins is located on top of said cylindrical tube and four rectangular fins are arranged on lateral sides of said cylindrical tube pointing downward so as to prevent ice and water from being collected on said cylindrical tube.

15. A method of operating a convection current vacuum freeze drying apparatus including a controller unit, a database storing specific freeze drying settings for different products, a drying chamber unit, an ice condenser unit having a plurality of elongate heat exchange tubes with fins that substantially occupies an internal volume of said ice condenser unit, a refrigerator unit, a cooling tower unit, a main vacuum pump unit, an auxiliary vacuum pump unit, a heater unit, said method comprising:

loading said specific freeze drying settings for a specific product from said database into said controller unit, whereupon said controller unit is operable to cause said convection current vacuum freeze drying apparatus to perform the following operational steps;

performing a preliminary convection current vacuum freeze drying step which includes turning on said cooling tower unit, turning on said refrigerator unit by a rate of 5°

C./minute, loading said products, avoid overloading of said vacuum pump unit, and turning on said vacuum pump unit at a rate of 5%/minute;

performing a primary convection current vacuum freeze drying step by lowering the temperature and pressure to a sublimation triple point temperature;

performing a secondary convection current vacuum freeze drying step by increasing the temperature to further dry said product; and

performing a post convection current vacuum freeze drying step by increasing said pressure and lowering said temperature to an ambient condition.

16. The method of claim 15 wherein performing said primary convection current vacuum freeze drying step further comprising increasing the freezing rate to accelerate lowering the temperature of said product to a triple point (or sublimation) by using natural convection currents created by said plurality of elongate heat exchange tubes with fins.

17. The method of claim 15 wherein performing said primary convection current vacuum freeze drying step further comprising accelerating lowering the pressure inside said ice condenser unit by using said auxiliary vacuum pump unit in addition to said primary vacuum pump unit.

18. The method of claim 15 wherein performing said secondary convection current vacuum freeze drying step further comprises increasing the temperature to said product inside said dryer unit by circulating hot water vapors from said heater unit by means of a plurality of tubes directly contacted metal surfaces where said products are deposited.

19. The method of claim 15 wherein said operational steps further comprises an ice defrosting step by increasing the temperature inside said ice condenser unit to defrost all ice formation on said plurality of first elongate heat exchange tubes.

20. sensing real-time freeze drying settings for each of said preliminary convection current vacuum freeze drying step, said primary convection current vacuum freeze drying step, said secondary convection current vacuum freeze drying step, and said post convection current vacuum freeze drying step, wherein said specific freeze drying settings further comprise temperatures, pressures, predetermined time durations, flow rates, pump rates, open or close states of valves, and freezing rates;

and

comparing said real-time freeze drying settings with said specific freeze drying settings stored in said database, if said real-time vacuum freeze drying settings are different from said specific vacuum freeze drying settings than predetermined levels, adjusting said real-time vacuum freeze drying settings;

otherwise, continuing said operational steps.