Portable viscometer

• US 10,451,532 B2
• Filed: 04/26/2011
• Issued: 10/22/2019
• Est. Priority Date: 04/26/2010
• Status: Active Grant

• Current Assignee: RheoSense, Inc.
• Original Assignee: RheoSense, Inc.
• Inventors: Baek, Seong-Gi
• Primary Examiner(s): Caputo, Lisa M
• Assistant Examiner(s): Devito, Alex
• Application Number:
  US13/094,710
• Publication Number:
  US 20120096929A1
• Time in Patent Office: 3,101 Days
• Field of Search: 73 5413
• CPC Class Codes: G01N 11/08 by measuring pressure required to produce a known flow

Abstract

A portable viscometer includes a pump mechanism which cooperates with a positive displacement sample container referred to as a positive displacement pipette, for dispensing, at a known flow rate, a sample of liquid for which viscosity is desired to be determined. The dispensed liquid flows through a flow through miniature viscosity sensor having at least two pressure sensors which measure the pressure drop of the liquid as it flows through a rectangular flow channel, the pressure drop at the known flow rate being proportional to the viscosity. A controller controls operation of the viscometer and processes sensor data, and the resulting measurements of viscosity can be displayed on a display. The positive displacement pipette is removably positioned in the viscometer so that it can be removed from the viscometer when a viscosity test is completed and replaced with another positive displacement pipette containing another liquid to be tested.

Claims

1. A portable viscometer comprising:

a viscosity sensor having a rectangular liquid flow channel with an interior space having four sides, wherein the interior space has a fixed depth, a liquid inlet connector coupled to the rectangular liquid flow channel, and at least two separate pressure sensors positioned along the rectangular liquid flow channel that measure a pressure drop of fully developed flow of a liquid flowing through the rectangular liquid flow channel based on an amount of deflection of at least a portion of a side wall of the rectangular liquid flow channel;

a dispensing pump mechanism adapted to couple with a positive displacement pipette that is adapted to contain a liquid, for which a measurement of viscosity is desired, so that operation of the dispensing pump mechanism, in cooperation with the positive displacement pipette, dispenses the liquid from the positive displacement pipette, and the viscosity sensor adapted to couple directly with the positive displacement pipette through the liquid inlet connector so that the liquid for which a measurement of viscosity is desired is forced into the viscosity sensor through the liquid inlet connector when dispensed from the positive displacement pipette; and

a controller that controls operation of the viscometer and processes sensor data, the controller configured to control the viscosity sensor to measure, with the at least two separate pressure sensors, pressures of the liquid flowing through the rectangular liquid flow channel at an initially set flow rate, and automatically determine a flow rate of the liquid, that is distinct from the initially set flow rate, based on the pressures with the at least two separate pressure sensors, so that the liquid is subsequently injected into the rectangular liquid flow channel at the determined flow rate corresponding to subsequent pressures measured by the at least two separate pressure sensors, wherein the at least two separate pressure sensors include a first sensor and a second sensor that is separate from the first sensor, and the controller is further configured to determine whether the pressures measured with the at least two separate pressure sensors are less than threshold pressure for the viscosity measurement, including determining that at least one of the pressure measured with the first pressure sensor and the pressure measured with the second pressure sensor is less than the threshold pressure for the viscosity measurement and increase the flow rate of the liquid so that pressures, measured by the at least two separate pressure sensors, of the liquid flowing through the rectangular liquid flow channel at the increased flow rate are greater than the threshold pressure.

2. The portable viscometer according to claim 1, additionally including a display that shows test results.

3. The portable viscometer according to claim 1, wherein the controller includes a programmed microcontroller.

4. The portable viscometer according to claim 3, wherein the controller includes a user interface for inputting test variables.

5. The portable viscometer according to claim 1, wherein the positive displacement pipette includes a pipette barrel, and a pipette plunger sealingly and slidably positioned within the pipette barrel, wherein the pipette plunger includes a plunger end portion that extends from the pipette barrel by which the pipette plunger can be slidingly moved in the pipette barrel.

6. The portable viscometer according to claim 5, wherein the pipette plunger is slidingly movable in two opposite directions with respect to the pipette barrel, movement in a filling direction providing for filling of the pipette barrel with a liquid and movement in a dispensing direction providing for dispensing of liquid from the pipette barrel.

7. The portable viscometer according to claim 6, wherein the dispensing pump mechanism is adapted to move the pipette plunger in the dispensing direction with respect to the pipette barrel at a known rate to dispense the liquid in the pipette barrel from the pipette barrel at a known flow rate.

8. The portable viscometer according to claim 7, wherein the dispensing pump mechanism includes a motor, a lead screw coupled to the motor so that operation of the motor results in rotation of the lead screw, and a push back coupled to the lead screw so that rotation of the lead screw results in linear movement of the push back, said push back also coupled to the plunger end portion whereby linear movement of the push back moves the pipette plunger in the dispensing direction.

9. The portable viscometer according to claim 8, wherein the controller controls operation of the motor.

10. The portable viscometer according to claim 7, additionally including mounting mechanism for removably mounting the positive displacement pipette in the viscometer.

11. The portable viscometer according to claim 1, additionally including mounting mechanism for removably mounting the positive displacement pipette in the viscometer.

12. The portable viscometer according to claim 1, wherein the viscosity sensor comprises:

a monolithic sensor plate having (i) a smooth sensing surface corresponding to the side wall of the rectangular liquid flow channel and (ii) a plurality of separate pressure sensors at different locations; and

a channel substrate with at least one flow channel formed therein having three side walls, a flow channel entrance, and a flow channel exit, wherein a combination of the channel substrate and the monolithic sensor plate collectively enables full containment of liquid during flow through the at least one flow channel, and the at least two separate pressure sensors of the plurality of separate pressure sensors in the monolithic sensor plate are positioned along the at least one flow channel sufficiently away from the flow channel entrance and flow channel exit so that a pressure drop of fully developed flow of the liquid in the at least one flow channel is measured as the liquid flows in the flow channel.

13. The portable viscometer according to claim 12, wherein the monolithic sensor plate includes a semiconductor material.

14. The portable viscometer according to claim 12, wherein the flow channel has a depth and the depth is greater than 1 micrometer and less than 1 mm.

15. The portable viscometer according to claim 1, wherein the portable viscometer stores a database of known viscosity values for a plurality of liquids.

16. The portable viscometer according to claim 1, wherein the viscometer stores a history of measured viscosity values.

17. The portable viscometer according to claim 1, wherein the controller includes communication means to enable communication between the controller and a remote computer.

18. The portable viscometer according to claim 1, additionally including at least one temperature control device to control the temperature of the liquid for which a measurement of viscosity is desired.

19. The portable viscometer according to claim 11, wherein the at least one temperature control device controls the temperature of the liquid for which a measurement of viscosity is desired in the positive displacement pipette prior to the liquid in the positive displacement pipette being forced into the viscosity sensor.

20. The portable viscometer according to claim 12, wherein the at least one temperature control device controls the temperature of the liquid for which a measurement of viscosity is desired as the liquid flows through the viscosity sensor.

21. The portable viscometer according to claim 1, wherein the at least two pressure sensors are positioned directly on a wall of the flow channel.

22. The portable viscometer according to claim 1, wherein the controller is configured to control the dispensing pump mechanism to dispense the liquid from the positive displacement pipette at the determined flow rate so that the liquid is injected into the rectangular liquid flow channel at the determined flow rate.

23. A portable viscometer comprising:

a dispensing pump mechanism;

a viscosity sensor having a rectangular liquid flow channel with an interior space having four sides, wherein the interior space has a fixed depth, a liquid inlet connector coupled to the rectangular liquid flow channel, and at least two separate pressure sensors positioned along the rectangular liquid flow channel that measure a pressure drop of fully developed flow of a liquid flowing through the rectangular liquid flow channel based on an amount of deflection of at least a portion of a side wall of the rectangular liquid flow channel;

a mounting mechanism adapted to removably mount a positive displacement pipette adapted to contain a liquid for which a measurement of viscosity is desired, said mounting mechanism adapted to mount the positive displacement pipette in position to cooperate with the dispensing pump mechanism so that the positive displacement pipette couples directly with the viscosity sensor through the liquid inlet connector and operation of the dispensing pump mechanism dispenses the liquid from the positive displacement pipette, and to cooperate with the viscosity sensor so that the liquid for which a measurement of viscosity is desired is forced into the viscosity sensor through the liquid inlet connector when dispensed from the positive displacement pipette; and

a controller that controls operation of the viscometer and processes sensor data, the controller configured to control the viscosity sensor to measure, with the at least two separate pressure sensors, pressures of the liquid flowing through the rectangular liquid flow channel at an initially set flow rate, and automatically determine a flow rate of the liquid, that is distinct from the initially set flow rate, based on the pressures with the at least two separate pressure sensors, so that the liquid is subsequently injected into the rectangular liquid flow channel at the determined flow rate corresponding to subsequent pressures measured by the at least two separate pressure sensors, wherein the at least two separate pressure sensors include a first sensor and a second sensor that is separate from the first sensor, and the controller is further configured to determine whether the pressures measured with the at least two separate pressure sensors are less than threshold pressure for the viscosity measurement, including determining that at least one of the pressure measured with the first pressure sensor and the pressure measured with the second pressure sensor is less than the threshold pressure for the viscosity measurement and increase the flow rate of the liquid so that pressures, measured by the at least two separate pressure sensors, of the liquid flowing through the rectangular liquid flow channel at the increased flow rate are greater than the threshold pressure.

24. The portable viscometer according to claim 23, additionally including at least one temperature control device to control the temperature of the liquid for which a measurement of viscosity is desired.

25. The portable viscometer according to claim 24, wherein the at least one temperature control device cooperates with the mounting mechanism to control the temperature of the liquid for which a measurement of viscosity is desired in the positive displacement pipette when the positive displacement pipette is mounted in the mounting mechanism prior to the liquid being forced from the positive displacement pipette into the viscosity sensor.

26. The portable viscometer according to claim 24, wherein the at least one temperature control device controls the temperature of the liquid for which a measurement of viscosity is desired as the liquid flows through the viscosity sensor.

27. The portable viscometer according to claim 23, wherein the dispensing pump mechanism includes a motor, a lead screw coupled to the motor so that operation of the motor results in rotation of the lead screw, and a push back coupled to the lead screw so that rotation of the lead screw results in linear movement of the push back, said push back adapted to mate with an end of a plunger extending from the positive displacement pipette when mounted in the mounting mechanism whereby linear movement of the push back moves the pipette plunger in a dispensing direction at a known rate to dispense the liquid from the positive displacement pipette at a known flow rate into the viscosity sensor.

28. A method of obtaining a measurement of viscosity of a liquid for which a measurement of viscosity is desired, comprising the steps of:

obtaining a portable viscometer comprising;

a dispensing pump mechanism;

a viscosity sensor having a rectangular liquid flow channel with an interior space having four sides, wherein the interior space has a fixed depth, a liquid inlet connector coupled to the rectangular liquid flow channel, and at least two separate pressure sensors positioned along the rectangular liquid flow channel that measure a pressure drop of fully developed flow of a liquid flowing through the rectangular liquid flow channel based on an amount of deflection of at least a portion of a side wall of the rectangular liquid flow channel;

a mounting mechanism adapted to removably mount a positive displacement pipette adapted to contain a sample liquid for which a measurement of viscosity is desired, said mounting mechanism adapted to mount the positive displacement pipette in position to cooperate with the dispensing pump mechanism so that the positive displacement pipette couples directly with the viscosity sensor through the liquid inlet connector and operation of the dispensing pump mechanism dispenses the sample liquid from the positive displacement pipette, and to cooperate with the viscosity sensor so that the sample liquid for which a measurement of viscosity is desired is forced into the viscosity sensor through the liquid inlet connector when dispensed from the positive displacement pipette; and

a controller that controls operation of the viscometer and processes sensor data, the controller configured to control the viscosity sensor to measure, with the at least two separate pressure sensors, pressures of the liquid flowing through the rectangular liquid flow channel at an initially set flow rate, and automatically determine a flow rate of the liquid, that is distinct from the initially set flow rate, based on the pressures with the at least two separate pressure sensors, so that the liquid is subsequently injected into the rectangular liquid flow channel at the determined flow rate corresponding to subsequent pressures measured by the at least two separate pressure sensors;

obtaining a positive displacement pipette containing a liquid for which a measurement of viscosity is desired;

placing the positive displacement pipette containing the liquid for which a measurement of viscosity is desired in the mounting mechanism; and

operating the portable viscometer to obtain a measurement of the viscosity of the liquid, for which a measurement of viscosity is desired, contained in the positive displacement pipette while the liquid flows through the portable viscometer, wherein the at least two separate pressure sensors include a first sensor and a second sensor that is separate from the first sensor, and the controller is further configured to determine whether the pressures measured with the at least two separate pressure sensors are less than threshold pressure for the viscosity measurement, including determining that at least one of the pressure measured with the first pressure sensor and the pressure measured with the second pressure sensor is less than the threshold pressure for the viscosity measurement and increase the flow rate of the liquid so that pressures, measured by the at least two separate pressure sensors, of the liquid flowing through the rectangular liquid flow channel at the increased flow rate are greater than the threshold pressure.