Synthetic blood vessels and uses thereof
First Claim
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1. A method of determining the risk for a cerebrovascular dysfunction in a subject in need thereof comprising:
- i) providing a synthetic blood vessel;
ii) providing an Aβ
peptide;
iii) contacting the synthetic blood vessel with a sample from the subject; and
iv) determining the level of Aβ
deposition or transport in the sample,wherein the subject has an increased risk for a cerebrovascular dysfunction if the level of Aβ
deposition is increased or if Aβ
transport is reduced.
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Abstract
The present invention provides a synthetic blood vessel and use thereof in drug screening, drug delivery and prognoses of cerebrovascular dysfunction.
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Citations
7 Claims
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1. A method of determining the risk for a cerebrovascular dysfunction in a subject in need thereof comprising:
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i) providing a synthetic blood vessel; ii) providing an Aβ
peptide;iii) contacting the synthetic blood vessel with a sample from the subject; and iv) determining the level of Aβ
deposition or transport in the sample,wherein the subject has an increased risk for a cerebrovascular dysfunction if the level of Aβ
deposition is increased or if Aβ
transport is reduced.- View Dependent Claims (2, 3, 4, 5, 6, 7)
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Specification