Wipe for killing spores

• US 10,455,838 B2
• Filed: 09/16/2016
• Issued: 10/29/2019
• Est. Priority Date: 04/28/2014
• Status: Active Grant

• Current Assignee: American Sterilizer Company (Steris Corporation)
• Original Assignee: American Sterilizer Company (Steris Corporation)
• Inventors: Burke, Peter A., Leggett, Mark James, Centanni, Michael A.
• Primary Examiner(s): Yoo, Regina M
• Application Number:
  US15/267,459
• Publication Number:
  US 20170000117A1
• Time in Patent Office: 1,138 Days
• CPC Class Codes: A01N 25/34 Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
• CPC Class Codes: A01N 37/16 containing the group; Thio analogues thereof
• CPC Class Codes: A01N 59/00 Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/327 Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
• CPC Class Codes: A61K 33/40 Peroxides
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61K 8/0208 Tissues; Wipes; Patches
• CPC Class Codes: A61K 8/22 Peroxides; Oxygen; Ozone
• CPC Class Codes: A61K 9/0014 Skin, i.e. galenical aspects of topical compositions non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00
• CPC Class Codes: A61K 9/7007 Drug-containing films, membranes or sheets A61K9/0041, A61K9/0043, A61K9/006, A61K9/0063 take precedence
• CPC Class Codes: A61L 2/0088 Liquid substances
• CPC Class Codes: A61L 2/186 Peroxide solutions
• CPC Class Codes: A61L 2202/21 Pharmaceuticals, e.g. medicaments, artificial body parts
• CPC Class Codes: A61L 2202/24 Medical instruments, e.g. endoscopes, catheters, sharps
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: B65D 75/30 Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
• CPC Class Codes: B65D 75/5805 for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness

Abstract

This invention relates to a wipe for killing spores comprising an absorbent sheet holding an aqueous composition and a sealed package containing the absorbent sheet, wherein the aqueous composition comprises water, an antimicrobial agent and a peroxide. The invention also relates to a process for killing spores using the above-indicated wipe.

Claims

1. A process for killing bacterial spores positioned on a substrate, comprising:

contacting the bacterial spores with an aqueous composition using an absorbent sheet, the aqueous composition consisting essentially of water, peracetic acid, acetic acid, sulfuric acid, and hydrogen peroxide, the concentration of the hydrogen peroxide in the water being in the range from 0.1 to 0.8% by weight, the concentration of the peracetic acid being in the range from 0.005 to 0.08% by weight, the weight ratio of the peracetic acid to the hydrogen peroxide being in the range from 0.001 to 0.1, the concentration of acetic acid being in the range from 0.001 to 0.3% by weight, and the concentration of sulfuric acid being in the range from 0.001 to 0.3% by weight; and

maintaining the aqueous composition in contact with the bacterial spores at a temperature in the range from about 1°

C. to about 40°

C. for an effective period of time to effect at least a 4 log reduction in the number of bacterial spores capable of returning to vegetative growth.

2. The process of claim 1 wherein the absorbent substrate is made of a material comprising brass, copper, aluminum, stainless steel, carbon steel, rubber, plastic, glass, wood, painted surface, or a combination of two or more thereof.

3. The process of claim 1 wherein the absorbent substrate comprises a table top, counter top, floor, wall, ceiling, window, door, door handle, sink, faucet, toilet or toilet seat.

4. The process of claim 1 wherein the absorbent substrate comprises a medical, dental, pharmaceutical, veterinary or mortuary device.

5. The process of claim 1 wherein the effective period of time is from about 30 seconds to about 20 minutes.

6. The process of claim 1 wherein the bacterial spores comprise bacteria of the Bacillus or Clostridia genera.

7. The process of claim 1 wherein the bacterial spores comprise Geobacillus stearothermophilus, Bacillus atrophaeus, Bacillus subtilis, Bacillus pumilus, Bacillus coagulans, Clostridium sporogenes, Bacillus subtilis globigii, Bacillus cereus, Bacillus circulans, Bacillus anthracis, or a mixture of two or more thereof.

8. The process of claim 1 wherein the bacterial spores comprise one or more Bacillus subtilis strains.

9. The process of claim 1 wherein the aqueous composition is maintained in contact with the bacterial spores for an effective period of time to effect at least a 5 log reduction in the number of bacterial spores capable of returning to vegetative growth.

10. The process of claim 1 wherein the aqueous composition is maintained in contact with the bacterial spores for an effective period of time to effect at least a 6 log reduction in the number of bacterial spores capable of returning to vegetative growth.