Devices for detecting organ contents using impedance and methods of using the same to provide various therapies

• US 10,456,060 B2
• Filed: 02/22/2013
• Issued: 10/29/2019
• Est. Priority Date: 02/22/2012
• Status: Active Grant

• Current Assignee: 3DT Holdings LLC
• Original Assignee: Ghassan S. Kassab
• Inventors: Kassab, Ghassan S.
• Primary Examiner(s): Fernandes, Patrick
• Application Number:
  US13/775,099
• Publication Number:
  US 20130267867A1
• Time in Patent Office: 2,440 Days
• Field of Search: 600547
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/4238 stomach
• CPC Class Codes: A61B 5/4836 Diagnosis combined with treatment in closed-loop systems or methods A61B5/0036 takes precedence

Abstract

Devices for detecting organ contents using impedance and methods of using the same to provide various therapies. In an exemplary embodiment of a device for detecting organ contents of the present disclosure, the device comprises a body having a detector coupled thereto, the device configured for placement at or near an outside of an organ and operable to detect contents on an inside of the organ using impedance.

Claims

1. A device for detecting organ contents, the device comprising:

a body having a detector coupled directly to the body, and at least one detector aperture defined within the body and the at least one detector aperture positioned outside and immediately adjacent the detector, the detector comprising a pair of detection electrodes and a pair of excitation electrodes and the at least one detector aperture sized and shaped to minimize interference that would compromise data obtained by the detector, the at least one detector aperture extending a length from a start of one electrode of the pair of detection electrodes or the pair of excitation electrodes to a start of another electrode of the pair of detection electrodes or the pair of excitation electrodes;

the body configured for external placement at or near an outside of an organ, but not within or surrounding the organ or within a lumen thereof, and the detector configured to both detect a presence or absence of contents within the lumen of the organ using impedance and to distinguish between any contents detected over time based on conductance data by obtaining first conductance data when solid contents are within the lumen, by obtaining second conductance data when liquid contents are within the lumen, and identifying a difference between the first conductance data and the second conductance data.

2. The device of claim 1, wherein the body is configured as a patch and the organ is selected from a group consisting of a stomach, an intestine, a bladder, and a lung.

3. The device of claim 1, wherein the detection electrodes of the detector are positioned on the body in between the pair of excitation electrodes of the detector.

4. The device of claim 3, wherein the pair of excitation electrodes are spaced apart from one another sufficient to generate a field that extends to an inside of the organ.

5. The device of claim 4, wherein the pair of detection electrodes is capable of detecting the field generated by the pair of excitation electrodes.

6. The device of claim 1, wherein the detector is operable to detect whether or not an inside of the organ has a liquid content therein.

7. The device of claim 6, wherein the detector is operable to detect changes in an amount of the liquid content inside of the organ.

8. The device of claim 1, wherein the detector is operable to detect whether or not an inside of the organ has a solid content therein.

9. The device of claim 8, wherein the detector is operable to detect changes in an amount of the solid content inside of the organ.

10. The device of claim 1, further comprising:

an adhesive pad coupled to the body, the adhesive pad configured to secure the device to the outside of the organ.

11. The device of claim 1, further comprising:

at least one suture aperture defined within the body, the at least one suture aperture sized and shaped to receive at least one suture therethrough to secure the device to the outside of the organ.

12. The device of claim 1, further comprising:

a power source coupled directly to the body and operably connected to the detector, the power source configured to provide power to the detector so to operate the detector.

13. The device of claim 1, further comprising:

an internal memory coupled directly to the body and operably connected to the detector, the internal memory operable to store conductance data obtained by the detector.

14. The device of claim 11, wherein the body further comprises one or more tabs, wherein the at least one suture aperture is defined within the one or more tabs.

15. A method for using a device, the method comprising the steps of:

positioning the device at or near an outside of an organ of a patient within the patient'"'"'s body, but not within the organ or within a lumen of said organ, the device comprising a body having a detector coupled directly to the body, a power source coupled directly to the body and operably connected to the detector, and at least one detector aperture defined within the body and positioned outside the detector, the detector comprising a pair of detection electrodes and a pair of excitation electrodes, the at least one detector aperture extending a length from a start of one electrode of the pair of detection electrodes or the pair of excitation electrodes to a start of another electrode of the pair of detection electrodes or the pair of excitation electrodes, the power source configured to provide power to the detector so to operate the detector, the at least one detector aperture sized and shaped to minimize interference that would compromise data obtained by the detector, and the detector configured to both detect a presence or absence of contents within the lumen of the organ using impedance and distinguish between any contents detected over time based on conductance data by obtaining first conductance data when solid contents are within the lumen, by obtaining second conductance data when liquid contents are within the lumen, and identifying a difference between the first conductance data and the second conductance data; and

operating the device to detect contents within the lumen of the organ and distinguish between any contents detected therein over time.

16. The method of claim 15, wherein the operating step is performed by activating the detector to obtain conductance data, the conductance data indicative of the contents on the lumen of the organ.

17. The method of claim 15, wherein the positioning step is performed to position the device at or near the outside of an organ selected from a group consisting of a stomach, an intestine, a bladder, a lung, and a heart.

18. The method of claim 17, wherein the operating step yields conductance data from the detector, the conductance data indicative of a change in an amount of a liquid content on the inside of the organ.

19. The method of claim 15, further comprising:

administering a therapy to the patient based upon the contents detected on an inside of the organ.

20. A device for detecting organ contents, the device comprising:

a body having a detector, a power source coupled directly to the body and operably connected to the detector, an internal memory coupled directly to the body and operably connected to the detector, and a transmitter coupled directly to the body, wherein the body is configured as a patch, the power source is configured to provide power to the detector so to operate the detector, the internal memory is operable to store conductance data obtained by the detector, the transmitter operable to transmit conductance data to an external system, and the detector comprises a pair of detection electrodes positioned on the body in between a pair of excitation electrodes;

a pair of detector apertures on either side of the detector, one detector aperture of the pair of detector apertures disposed on a side of the detector, and the other detector aperture from the pair of detector apertures disposed on another side of the detector, each detector aperture of the pair of detector apertures defined within the body;

each of the detector apertures extending a length from a start of one electrode of the pair of detection electrodes or the pair of excitation electrodes to a start of another electrode of the pair of detection electrodes or the pair of excitation electrodes;

the body configured for external placement at or near an outside of an organ, but not within or surrounding the organ or within a lumen thereof, and the detector configured to both detect a presence or absence of contents within the lumen of the organ using impedance and distinguish between any contents detected therein over time based on conductance data by obtaining first conductance data when solid contents are within the lumen, by obtaining second conductance data when liquid contents are within the lumen, and identifying a difference between the first conductance data and the second conductance data;

wherein the pair of excitation electrodes are spaced apart from one another on the body sufficient to generate a field that extends into the lumen of the organ.