Thrombo-embolic protection and embolectomy/thrombectomy devices and methods

• US 10,456,159 B2
• Filed: 10/15/2015
• Issued: 10/29/2019
• Est. Priority Date: 10/17/2014
• Status: Active Grant

• Current Assignee: TransMed7, LLC
• Original Assignee: TransMed7, LLC
• Inventors: Vetter, James W, Vetter, Eugene H
• Primary Examiner(s): David, Shaun L
• Application Number:
  US14/884,491
• Publication Number:
  US 20160287283A1
• Time in Patent Office: 1,475 Days
• Field of Search: None
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 2017/22079 with suction of debris
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/320716 comprising means for preventing embolism by dislodged material
• CPC Class Codes: A61B 2017/320733 with a flexible cutting or scraping element, e.g. with a whip-like distal filament member
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting

Abstract

A device for intra-vascular embolic-thrombolic protection, as well as embolectomy/thrombectomy and atherectomy interventional procedures and methods. At least a portion of the working end of the device may be formed monolithically from a single hypodermic tube, or may be formed of monolithic inner and outer tubes with fixed or movable guide wire elements and imaging modalities. The device may comprise structures enabling coring, expansion within a vascular structure and vascular wall shaving, as well as filtration, stabilization and capturing of thrombotic or embolitic material during an intervention procedure.

Claims

1. A device, comprising:

a handle;

a first tube coupled to the handle, a distal portion of the first tube defining a work element comprising;

a proximal end;

a distal end; and

a plurality of slats formed by cutting the first tube between the proximal end and the distal end of the work element such that each of the plurality of slats spans a non-zero radial angle from the proximal end of the work element to the distal end of the work element;

a second tube, the second tube being coupled to proximal ends of the plurality of slats and being configured to move distally within the first tube;

wherein distally-directed movement of the second tube causes the plurality of slats to selectively expand away from the second tube, and wherein further distally-directed movement of the second tube causes the plurality of slats to expand further away from the second tube until a proximal portion of each the plurality of slats buckles and inverts back toward the second tube.

2. The device of claim 1, further comprising a nose cone coupled to the distal end of the work element.

3. The device of claim 2, wherein the nose cone comprises a plurality of cutting elements.

4. The device of claim 2, wherein a distal end of each of the plurality of slats is coupled to the nose cone.

5. The device of claim 4, wherein differential rotation of the nose cone relative to the first tube or differential rotation of the first tube relative to the nose cone causes radial movement of the plurality of slats.

6. The device of claim 2, wherein a distal end of the second tube is coupled to the nose cone.

7. The device of claim 6, configured such that differential rotation of the first and second tubes causes the plurality of slats to move in a radial direction.

8. The device of claim 1, wherein the plurality of slats in at least a portion of the work element form a spiral pattern.

9. The device of claim 1, wherein the plurality of slats in at least a portion of the work element are substantially parallel to a long axis of the first tube.

10. The device of claim 1, wherein the plurality of slats are configured to selectively bow radially outward and radially inward between the proximal end of the work element and the distal end of the work element.

11. The device of claim 1, wherein the plurality of slats are configured to selectively bow radially outward and bow radially inward in response to differential rotation of the nose cone and the first tube.

12. The device of claim 1, wherein the plurality of slats are configured to selectively bow radially outward and bow radially inward in response to respective torsional forces applied to the first tube.

13. The device of claim 1, wherein the bucking and inversion of the proximal portion of each of the plurality of slats is configured causes them to assume an angle of less than 90 degrees with a corresponding distal portion thereof.

14. The device of claim 1, wherein at least the proximal portion of each of the plurality of slats is configured to be drawn toward the distal end of the work element until a circumferential rim is formed.

15. The device of claim 1, wherein each of the plurality of slats forms a living hinge that is formed from the first tube.

16. The device of claim 1, wherein each of the plurality of slats is formed by laser cutting the distal portion of the first tube along a predetermined path.

17. The device of claim 16, wherein at least a portion of the predetermined path forms a non-zero angle relative to a long axis of the first tube.

18. The device of claim 1, wherein at least one of the plurality of slats comprises a cutting edge.

19. The device of claim 1, configured as an embolectomy device.

20. The device of claim 1, configured as a thrombo-embolic protective device.

21. The device of claim 1, configured as an atherectomy device.

22. The device of claim 1, configured for insertion in a patient vasculature and configured, in operation, to enable blood flow at least from a point distal to the work element to a point proximal thereto.

23. The device of claim 1, wherein distal portions of the plurality of slats are stiffer than the proximal portions thereof.