Intraocular lens that improves overall vision where there is a local loss of retinal function

• US 10,456,242 B2
• Filed: 01/15/2018
• Issued: 10/29/2019
• Est. Priority Date: 03/10/2014
• Status: Active Grant

• Current Assignee: Amo Groningen B.V (Johnson & Johnson)
• Original Assignee: Amo Groningen B.V (Johnson & Johnson)
• Inventors: Rosen, Robert, Weeber, Hendrik A., Canovas Vidal, Carmen, Van Der Mooren, Marrie, Sellitri, Dora
• Primary Examiner(s): Prebilic, Paul B
• Application Number:
  US15/871,861
• Publication Number:
  US 20180221140A1
• Time in Patent Office: 652 Days
• CPC Class Codes: A61B 3/0025 characterised by electronic signal processing, e.g. eye models
• CPC Class Codes: A61B 3/028 for testing visual acuity; for determination of refraction, e.g. phoropters
• CPC Class Codes: A61B 3/1005 for measuring distances inside the eye, e.g. thickness of the cornea A61B3/11 takes precedence
• CPC Class Codes: A61B 3/103 for determining refraction, e.g. refractometers, skiascopes
• CPC Class Codes: A61B 3/107 for determining the shape or measuring the curvature of the cornea
• CPC Class Codes: A61B 3/14 Arrangements specially adapted for eye photography apparatus or arrangements for taking photographs per se G03B
• CPC Class Codes: A61F 2/1602 Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes
• CPC Class Codes: A61F 2/1605 Anterior chamber lenses for use in addition to the natural lenses of the eyes, e.g. iris fixated, iris floating
• CPC Class Codes: A61F 2/1613 having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
• CPC Class Codes: A61F 2/1618 Multifocal lenses
• CPC Class Codes: A61F 2/1637 Correcting aberrations caused by inhomogeneities; correcting intrinsic aberrations, e.g. of the cornea, of the surface of the natural lens, aspheric, cylindrical, toric lenses
• CPC Class Codes: A61F 2/164 Aspheric lenses
• CPC Class Codes: A61F 2/1645 Toric lenses
• CPC Class Codes: A61F 2/1648 Multipart lenses
• CPC Class Codes: A61F 2/1654 Diffractive lenses
• CPC Class Codes: A61F 2/1656 Fresnel lenses, prisms or plates
• CPC Class Codes: A61F 2/1659 having variable absorption coefficient for electromagnetic radiation, e.g. photochromic lenses
• CPC Class Codes: A61F 2002/1681 having supporting structure for lens, e.g. haptics
• CPC Class Codes: A61F 2240/002 Designing or making customized prostheses

Abstract

Systems and methods are provided for improving overall vision in patients suffering from a loss of vision in a portion of the retina (e.g., loss of central vision) by providing symmetric or asymmetric optic with aspheric surface which redirects and/or focuses light incident on the eye at oblique angles onto a peripheral retinal location. The intraocular lens can include a redirection element (e.g., a prism, a diffractive element, or an optical component with a decentered GRIN profile) configured to direct incident light along a deflected optical axis and to focus an image at a location on the peripheral retina. Optical properties of the intraocular lens can be configured to improve or reduce peripheral errors at the location on the peripheral retina. One or more surfaces of the intraocular lens can be a toric surface, a higher order aspheric surface, an aspheric Zernike surface or a Biconic Zernike surface to reduce optical errors in an image produced at a peripheral retinal location by light incident at oblique angles.

Claims

1. An intraocular lens configured to improve vision for a patient'"'"'s eye, the intraocular lens comprising:

an optic comprising a first surface and a second surface opposite the first surface, the first surface and the second surface intersected by an optical axis, the optic being symmetric about the optical axis, wherein the first and the second surface of the optic are aspheric, the first surface having a first radius of curvature and a first conic constant and the second surface having a second radius of curvature and a second conic constant,

wherein the first surface of the optic is configured to face the cornea and the second surface of the optic is configured to face the retina when the optic is implanted in the patient'"'"'s eye,

wherein the first radius of curvature is less than the second radius of curvature,

wherein the first conic constant is greater than the second conic constant, and

wherein the optic is configured to improve image quality of an image produced by light incident on the patient'"'"'s eye at an oblique angle with respect to the optical axis and focused at a peripheral location disposed at a distance from the fovea and at an eccentricity between about 1 degree and about 25 degrees with respect to the optical axis at the fovea.

2. The intraocular lens of claim 1, wherein the image quality is improved by reducing coma at the peripheral retinal location.

3. The intraocular lens of claim 1, wherein the image quality is improved by reducing oblique astigmatism at the peripheral retinal location.

4. The intraocular lens of claim 1, wherein the oblique angle is between about 1 degree and about 30 degrees.

5. The intraocular lens of claim 1, wherein a modulation transfer function (MTF) of the intraocular lens for a spatial frequency of 30 cycles/mm for both the tangential and the sagittal foci at the peripheral retinal location is at least 0.3.

6. The intraocular lens of claim 1, wherein a modulation transfer function (MTF) of the intraocular lens for a spatial frequency of 100 cycles/mm for both the tangential and the sagittal foci at the fovea is at least 0.2.

7. The intraocular lens of claim 1, wherein the optic is a meniscus lens with a vertex curving inwards from edges of the optic.

8. The intraocular lens of claim 1, wherein one of the first or second surface comprises one or more diffractive elements.

9. The intraocular lens of claim 1, wherein the optic element includes prismatic features.

10. The intraocular lens of claim 1, wherein the first conic constant is greater than or equal to 10 and less than or equal to 1000.

11. The intraocular lens of claim 1, wherein the second conic constant is less than 10.

12. The intraocular lens of claim 1, wherein the optic has a thickness between about 0.25 mm and about 1.5 mm.

13. The intraocular lens of claim 1, wherein the peripheral retinal location is disposed at a distance less than about 3.0 mm from the fovea.