Dry powder inhaler

• US 10,456,535 B2
• Filed: 04/11/2017
• Issued: 10/29/2019
• Est. Priority Date: 05/23/2016
• Status: Active Grant

• Current Assignee: Presspart Manufacturing Ltd. (Heitkamp & Thumann KG)
• Original Assignee: Presspart Manufacturing Ltd. (Heitkamp & Thumann KG)
• Inventors: Hemy, Julian, Turner, Richard, Schmelzer, Hans-Peter, Schmitz, Dietmar, Hoffmann, Stefan, Sule, Ameet, Sule, Sunita, Seiler, Matthias, Bostock, George Alexander, Einari Laakso, Aki Hannu, Worth, Michael, Schumann, Matthew
• Primary Examiner(s): Boecker, Joseph D.
• Application Number:
  US15/484,232
• Publication Number:
  US 20170333646A1
• Time in Patent Office: 931 Days
• CPC Class Codes: A61M 11/00 Sprayers or atomisers specially adapted for therapeutic purposes in general B05B; aerosol containers B65D83/14
• CPC Class Codes: A61M 11/003 by passing the aerosol trough sieves or filters
• CPC Class Codes: A61M 15/0005 with means for agitating the medicament
• CPC Class Codes: A61M 15/0021 Mouthpieces therefor
• CPC Class Codes: A61M 15/0028 using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
• CPC Class Codes: A61M 15/0041 with movable piercing or cutting means
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2206/11 Laminar flow
• CPC Class Codes: A61M 2206/16 Rotating swirling helical flow, e.g. by tangential inflows

Abstract

The present invention relates to an inhaler device for delivering a dose of medicament in dry powder form from a container to a patient in need thereof. The inhaler comprises a swirl chamber in which particles of the medicament entrained in an airflow swirl upon inhalation thereby breaking up the agglomerates into finest dispersed powder.

Claims

1. An inhaler device comprising

an inhaler housing comprising at least one air inlet duct;

an elongated capsule chamber adapted for receiving a capsule which contains a dose of medicament in dry powder form, and wherein the capsule chamber has a longitudinal axis and is defined by a wall arrangement including a first and a second supporting wall portion opposing each other in a direction perpendicular to the longitudinal axis and first and second sidewall portions opposing each other in the direction of the longitudinal axis;

a mouthpiece portion through which the medicament in dry powder form is dispensable; and

at least first and second airflow paths which each extend between the at least one air inlet duct, the capsule chamber and the mouthpiece portion to enable an inhalation airflow formed upon inhalation to flow through the at least one air inlet duct via the capsule chamber and the mouthpiece portion such that the dose of medicament is entrained in air and dispensed through the mouthpiece portion;

wherein the first airflow path comprises at least a first intermediate duct extending from the at least one air inlet duct to a first capsule chamber inlet adjacent to the first sidewall portion, and at least a first outlet duct extending from a first capsule chamber outlet adjacent to the first sidewall portion in direction to the mouthpiece portion; and

the second airflow path comprises at least a second intermediate duct extending from the at least one air inlet duct to a second capsule chamber inlet adjacent to the second sidewall portion, and at least a second outlet duct extending from a second capsule chamber outlet adjacent to the second sidewall portion in direction to the mouthpiece portion,

wherein

the at least first and second outlet ducts extend, upon exit from the capsule chamber, towards a swirl chamber and are connected to it,

wherein said swirl chamber comprises a base from which an inner wall surrounding that base vertically extends towards a swirl chamber outlet and,

wherein the swirl chamber outlet is connected to the mouthpiece portion and encloses a flow cross-section area which is smaller than an area of the base surrounded by the inner wall.

2. An inhaler device according to claim 1, wherein the at least first and second outlet ducts extend, upon exit from the capsule chamber, towards the swirl chamber in a helix shaped manner.

3. An inhaler device according to claim 1, wherein the at least first and second outlet ducts that extend towards the swirl chamber converge, spiraling inwards, or diverge, spiraling outwards from a vertical axis (180) along which the inner wall extends from the base.

4. An inhaler device according to claim 1, wherein the first and second outlet ducts are fed into the swirl chamber substantially parallel to the inner wall.

5. An inhaler device according to claim 1, wherein the first and second outlet ducts are fed into the swirl chamber through the base adjacent to the inner wall.

6. An inhaler device according to claim 1, wherein the swirl chamber comprises a dome like shape having a top, at which the swirl chamber outlet is located.

7. An inhaler device according to claim 1, wherein the swirl chamber is rotationally symmetrical to a vertical axis along which the inner wall extends from the base.

8. An inhaler device according to claim 1, wherein the inner wall forms a polygon surrounding the base.

9. An inhaler device according to claim 1, wherein the mouthpiece portion comprises a mouthpiece duct which extends from the swirl chamber to a mouthpiece dispensing opening.

10. An inhaler device according to claim 9, wherein a mesh is positioned in the mouthpiece duct, wherein the mesh extends perpendicular to a flow direction of the airflow.

11. An inhaler device according to claim 9, wherein at least one plate is positioned in the mouthpiece duct, wherein the plate extends in flow direction of the airflow.

12. An inhaler device according to claim 9, wherein a cross formed by two plates arranged perpendicular to each other is positioned in the mouthpiece duct, wherein the plates extend in flow direction of the airflow.

13. An inhaler device according to claim 1, characterized in that the first and second airflow paths are arranged such that during inhalation, the capsule having a longitudinal axis and first and second end sections delimiting the capsule on opposing ends located in the capsule chamber performs an oscillating movement in the capsule chamber parallel to the longitudinal axis of the capsule between the first and the second sidewall portions when an airflow is initiated through the at least first and the second airflow paths in a direction from the at least one air inlet duct towards the mouthpiece portion.

14. The inhaler device according to claim 1, further comprising a moveable piercing means located in the first and second sidewall portions of the capsule chamber for piercing the capsule located in the capsule chamber at first and second end sections of the capsule.