System and method to automatically maintain electrical stimulation intensity

• US 10,456,585 B2
• Filed: 03/22/2018
• Issued: 10/29/2019
• Est. Priority Date: 10/26/2006
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Thacker, James R., Haut, Harold, Nathan, Robert, Peterson, David K. L., Bradley, Kerry
• Primary Examiner(s): Levicky, William J
• Application Number:
  US15/933,194
• Publication Number:
  US 20180207432A1
• Time in Patent Office: 586 Days
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36146 specified by the stimulation parameters
• CPC Class Codes: A61N 1/36171 Frequency
• CPC Class Codes: A61N 1/36175 Pulse width or duty cycle
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

Tissue stimulation systems generally include a pulse generating device for generating electrical stimulation pulses, at least one implanted electrode for delivering the electrical stimulation pulses generated by the pulse generating device, and a programmer capable of communicating with the pulse generating device. Stimulation pulses may be defined by several parameters, such as pulse width and amplitude. In methods of stimulating the tissue with the stimulation system, a user may adjust one of the parameters such as pulse width. The programmer may automatically adjust the pulse amplitude in response to the change in pulse width in order to maintain a substantially constant effect of the stimulation pulses.

Claims

1. A system, comprising:

a programmer configured to instruct a stimulator to electrical energy by delivering electrical current to at least one electrode that is in contact with tissue of a patient to provide a stimulation effect, wherein the stimulation effect includes at least one of an evoked potential feature, an electroencephalogram (EEG) feature, or an electromyography (EMG) feature, wherein adjustable stimulation parameters are used to define the electrical current that provides the stimulation effect;

wherein the programmer is configured to automatically respond to a manual adjustment of at least a first one of the stimulation parameters by automatically adjusting at least a second of the stimulation parameters to maintain the stimulation effect using a defined relationship of the adjustable stimulation parameters to the stimulation effect.

2. The system of claim 1, wherein the defined relationship between the adjustable stimulation parameters and the stimulation effect includes a defined relationship of an amplitude and a pulse width to the stimulation effect, and the controller is configured to automatically respond to a manual adjustment of the amplitude by automatically adjusting the pulse width using the defined relationship to maintain the stimulation effect.

3. The system of claim 1, wherein the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of an amplitude and a pulse width to the stimulation effect, and the controller is configured to automatically respond to a manual adjustment of the pulse width by automatically adjusting the amplitude to maintain the stimulation effect.

4. The system of claim 1, wherein:

the stimulator is configured to deliver pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude;

the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of the amplitude, the pulse width and the pulse frequency to the stimulation effect; and

the controller is configured to automatically respond to a manual adjustment of the pulse frequency by automatically adjusting both the amplitude and the pulse width to maintain the stimulation effect.

5. A method, comprising:

delivering electrical current to at least one electrode that is in contact with tissue of a patient to provide a stimulation effect, wherein the stimulation effect includes at least one of an evoked potential feature, an electroencephalogram (EEG) feature, or an electromyography (EMG) feature, wherein adjustable stimulation parameters are used to define the delivered electrical current that provides the stimulation effect; and

adjusting at least a first one of the stimulation parameters, and then automatically adjusting at least a second of the stimulation parameters in response to adjusting the at least the first of the stimulation parameters, wherein the at least the second of the stimulation parameters is automatically adjusted to maintain the stimulation effect using a defined relationship of the adjustable stimulation parameters to the stimulation effect.

6. The method of claim 5, wherein adjusting the at least the first one of the stimulation parameters includes adjusting an amplitude.

7. The method of claim 6, wherein:

delivering electrical current includes delivering pulsed electrical current that has pulses that have a pulse width;

the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of the amplitude and the pulse width to the stimulation effect; and

automatically adjusting the at least the second of the stimulation parameters includes automatically adjusting the pulse width using the defined relationship.

8. The method of claim 5, wherein delivering electrical current includes delivering pulsed electrical current that has pulses that have a pulse width, and adjusting the at least the first one of the stimulation parameters includes adjusting the pulse width.

9. The method of claim 8, wherein:

the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of an amplitude and the pulse width to the stimulation effect; and

automatically adjusting the at least the second of the stimulation parameters includes automatically adjusting the amplitude of the pulses using the defined relationship.

10. The method of claim 5, wherein:

delivering electrical current includes delivering pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude;

the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of the amplitude, the pulse width and the pulse frequency to the stimulation effect;

adjusting the at least the first one of the stimulation parameters includes adjusting the pulse frequency of the pulsed electrical current; and

automatically adjusting the at least the second of the stimulation parameters includes using the defined relationship to automatically adjust the amplitude, or automatically adjust the pulse width, or automatically adjust both the amplitude and the pulse width.

11. The method of claim 5, wherein delivering electrical current includes delivering pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude;

the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of the amplitude, the pulse width and the pulse frequency to the stimulation effect;

adjusting the at least the first one of the stimulation parameters includes adjusting the amplitude; and

automatically adjusting the at least the second of the stimulation parameters includes using the defined relationship to automatically adjust the pulse frequency.

12. The method of claim 5, wherein the delivered electrical current includes delivering pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude;

the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of the amplitude, the pulse width and the pulse frequency to the stimulation effect;

adjusting the at least the first one of the stimulation parameters includes adjusting the pulse width; and

automatically adjusting the at least the second of the stimulation parameters includes using the defined relationship to automatically adjust the pulse frequency.

13. The method of claim 5, wherein the at least the first of the stimulation parameters or the at least the second of the stimulation parameters includes a pulse rise time, or a pulse fall time, or both the pulse rise time and the pulse fall time.

14. A non-transitory machine-readable medium including instructions, which when executed by a machine, cause the machine to:

instruct a stimulator to deliver electrical current to at least one electrode that is in contact with tissue of a patient to provide a stimulation effect, wherein the stimulation effect includes at least one of an evoked potential feature, an electroencephalogram (EEG) feature, or an electromyography (EMG) feature, wherein adjustable stimulation parameters are used to define the electrical current that provides the stimulation effect; and

automatically respond to a manual adjustment of at least a first one of the stimulation parameters by automatically adjusting at least a second of the stimulation parameters to maintain the stimulation effect using a defined relationship of the adjustable stimulation parameters to the stimulation effect.

15. The non-transitory machine-readable medium of claim 14, wherein the automatically respond includes automatically respond to an adjustment of an amplitude by automatically adjusting a pulse width to maintain the stimulation effect.

16. The non-transitory machine-readable medium of claim 14, wherein the automatically respond includes automatically respond to an adjustment of a pulse width by automatically adjusting an amplitude to maintain the stimulation effect.

17. The non-transitory machine-readable medium of claim 14, wherein:

the deliver electrical current includes deliver pulsed electrical current that has pulses and that has a pulse frequency and an amplitude;

the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of the amplitude, the pulse width and the pulse frequency to the stimulation effect; and

the automatically respond includes automatically respond to an adjustment of a pulse frequency by automatically adjusting the amplitude to maintain the stimulation effect using the defined relationship.

18. The non-transitory machine-readable medium of claim 14, wherein:

the deliver electrical current includes deliver pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency;

the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of the amplitude, the pulse width and the pulse frequency to the stimulation effect; and

the automatically respond includes automatically respond to an adjustment of a pulse frequency by automatically adjusting the pulse width to maintain the stimulation effect using the defined relationship.

19. The non-transitory machine-readable medium of claim 14, wherein:

the deliver electrical current includes deliver pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude;

the defined relationship of the adjustable stimulation parameters to the stimulation effect includes a defined relationship of the amplitude, the pulse width and the pulse frequency to the stimulation effect; and

the automatically respond includes automatically respond to an adjustment of a pulse frequency by automatically adjusting both the amplitude and the pulse width to maintain the stimulation effect using the defined relationship.

20. The non-transitory machine-readable medium of claim 14, wherein the at least the first of the stimulation parameters or the at least the second of the stimulation parameters includes a pulse rise time, or a pulse fall time, or both the pulse rise time and the pulse fall time.