Lipase variants and polynucleotides encoding same
First Claim
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1. A variant of a parent lipase, wherein the variant has at least 90% but less than 100% sequence identity to SEQ ID NO:
- 2, has lipase activity, comprises a substitution at position 92 and/or 96; and
remains unaltered at positions 231, 233 and 254 of SEQ ID NO;
2;
wherein the substitution at position 92 is Asp or Lys; and
wherein the substitution at position 96 is IIe, Leu or Thr.
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Abstract
The present invention relates to a variant of a parent lipase, wherein said variant has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, has lipase activity, comprises a substitution at a position corresponding to position 92 and/or 96; and remains unaltered at the positions corresponding to positions 231, 233 and 254 of SEQ ID NO: 2. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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Citations
16 Claims
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1. A variant of a parent lipase, wherein the variant has at least 90% but less than 100% sequence identity to SEQ ID NO:
- 2, has lipase activity, comprises a substitution at position 92 and/or 96; and
remains unaltered at positions 231, 233 and 254 of SEQ ID NO;
2;wherein the substitution at position 92 is Asp or Lys; and wherein the substitution at position 96 is IIe, Leu or Thr. - View Dependent Claims (2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
- 2, has lipase activity, comprises a substitution at position 92 and/or 96; and
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3. The variant of 1, wherein the parent lipase comprises or consists of SEQ ID NO:
- 2;
SEQ ID NO;
4;
or SEQ ID NO;
6.
- 2;
Specification