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Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties

  • US 10,463,276 B2
  • Filed: 11/03/2016
  • Issued: 11/05/2019
  • Est. Priority Date: 09/01/2009
  • Status: Active Grant
First Claim
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1. A device for measuring a mechanical property of a tissue for needle-free injection, the device comprising:

  • a probe configured to contact a surface of the tissue;

    an electromagnetic actuator coupled to the probe to move the probe laterally with respect to the surface of the tissue;

    a detector configured to measure a physical response of the tissue to the lateral movement of the probe;

    an electronic controller coupled to the actuator and the detector, the controller configured to move the probe laterally with respect to the surface of the tissue by driving the actuator using a stochastic sequence and determine the mechanical property of the tissue by using the measured response received from the detector when the stochastic sequence is used to drive the actuator; and

    a needle-free injector configured to control needle-free injection using the determined mechanical property.

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