Method and apparatus for providing data processing and control in a medical communication system

• US 10,463,310 B2
• Filed: 09/07/2015
• Issued: 11/05/2019
• Est. Priority Date: 05/14/2007
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Hayter, Gary Alan
• Primary Examiner(s): Mallari, Patricia
• Assistant Examiner(s): Catina, Michael A
• Application Number:
  US14/846,986
• Publication Number:
  US 20150374299A1
• Time in Patent Office: 1,520 Days
• CPC Class Codes: A61B 2560/0242 adapted to measure environmental factors, e.g. temperature, pollution
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/1451 for interstitial fluid
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61B 5/7405 using sound
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: A61B 5/7455 characterised by tactile indication, e.g. vibration or electrical stimulation

Abstract

Methods and apparatus for providing data processing and control for use in a medical communication system are provided.

Claims

1. An analyte monitoring system, comprising:

an in vivo analyte sensor for positioning in fluid contact with interstitial fluid under a skin layer and configured to generate a plurality of analyte signals corresponding to a monitored analyte level in the interstitial fluid; and

one or more processors configured to;

receive one or more data packets including at least a current value and a plurality of prior values, generated from the plurality of analyte signals;

determine a rate of change of the monitored analyte level based on the current value and the plurality of prior values;

select, from a plurality of bins each corresponding to a respective rate of change, a bin for the current value and plurality of prior values based on the determined rate of change, each bin of the plurality of bins being associated with a position of a trend indicator on a display coupled to the one or more processors, each position of the trend indicator associated with a different rate of change for the monitored analyte level;

dynamically modify an uncertainty parameter based on time spacing between the current value and the plurality of prior values; and

output the trend indicator on the display at the position associated with the selected bin to indicate the associated rate of change when the dynamically modified uncertainty parameter based on the time spacing between the current value and plurality of prior values does not exceed a predetermined threshold level.

2. The system of claim 1, wherein the one or more processors are further configured to generate an output notification when an adverse data condition of the analyte sensor is detected.

3. The system of claim 1, wherein the one or more processors are further configured to generate an output notification when an out of range temperature value associated with the received one or more data packets is detected.

4. The system of claim 1, wherein the one or more data packets include at least two data packets, and wherein the one or more processors are further configured to generate an output notification when a predefined persistent low condition associated with the one or more data packets is detected.

5. The system of claim 4, wherein the persistent low condition associated with the one or more data packets includes a condition of at least two consecutive signals from the one or more data packets being below a predetermined signal level.

6. The system of claim 5, wherein the predetermined signal level is associated with a failed analyte sensor state.

7. The system of claim 1, wherein the one or more processors are further configured to generate an output notification when an error condition of the analyte sensor is detected.

8. The system of claim 7, wherein the error condition of the analyte sensor includes unacceptable data quality of the one or more data packets.

9. The system of claim 1, further comprising an output unit configured to output one or more of an audible output signal or a vibratory output signal.

10. The system of claim 1, wherein the one or more processors are further configured to generate an output notification including an indication to replace the analyte sensor.

11. The system of claim 1, wherein the trend indicator depicts a change in the analyte level.

12. The system of claim 1, wherein the one or more processors are further configured to remove the trend indicator when the dynamically modified uncertainty parameter based on the time spacing between the current value and plurality of prior values exceeds the predetermined threshold level.

13. The system of claim 1, wherein the one or more processors are further configured to perform a flashing of the trend indicator.

14. The system of claim 1, wherein the one or more processors are further configured to change a characteristic of the trend indicator, including at least one of a change in color, a change in shape, or a change in size of the trend indicator.

15. The system of claim 1, wherein the one or more processors are further configured to perform at least one of a change in a length or a change in a width of the trend indicator.

16. The system of claim 1, wherein the in vivo analyte sensor comprises a plurality of electrodes including a working electrode comprising an analyte-responsive enzyme bonded to a polymer disposed on the working electrode.

17. The system of claim 16, wherein the analyte-responsive enzyme is chemically bonded to the polymer.

18. The system of claim 16, wherein the working electrode further comprises a mediator.

19. The system of claim 1, wherein the in vivo analyte sensor comprises a plurality of electrodes including a working electrode comprising a mediator bonded to a polymer disposed on the working electrode.

20. The system of claim 19, wherein the mediator is chemically bonded to the polymer.