Method for automatically detecting sepsis and displaying dynamic sepsis images in a hospital room

• US 10,468,135 B2
• Filed: 11/07/2014
• Issued: 11/05/2019
• Est. Priority Date: 02/06/2001
• Status: Active Grant

• Current Assignee: Lawrence A. Lynn
• Original Assignee: Lawrence A. Lynn
• Inventors: Lynn, Lawrence A., Lynn, Eric N.
• Primary Examiner(s): Nguyen, Trang T
• Application Number:
  US14/535,838
• Publication Number:
  US 20150066533A1
• Time in Patent Office: 1,824 Days
• Field of Search: 705 2, 705 3
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 30/20 for handling medical images, e.g. DICOM, HL7 or PACS
• CPC Class Codes: G16H 30/40 for processing medical images, e.g. editing
• CPC Class Codes: G16H 40/60 for the operation of medical equipment or devices
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients
• CPC Class Codes: H04N 9/87 Regeneration of colour television signals H04N9/80 takes precedence

Abstract

A system for automatically detecting and displaying sepsis images in a hospital system is described herein. In some examples, the system can include receiving data related to a plurality of physiological parameters from a patient over time, and identifying and organizing patterns of perturbations of the data. The system can also include analyzing the perturbations to identify known relational physiologic patterns and detecting a pattern of sepsis, the pattern being comprised of a plurality of perturbations and/or relational physiologic patterns. Furthermore, the system can include organizing and synthesizing the plurality of relational physiologic patterns into a set of sepsis images, which as an aggregate whole make up an image representation of the complex and dynamic state of sepsis, and displaying the sepsis images. The images can be color motion images of cascades which display the severities of individual perturbations and relational physiologic patterns along the cascade pattern.

Claims

1. A patient monitoring system for monitoring a plurality of patients in a healthcare system and automatically detecting sepsis among the plurality of patients and for displaying sepsis images in the healthcare system, comprising:

a plurality of local patient safety monitors, each of the plurality of local patient safety monitors configured to receive physiological measurements from at least a pulse oximeter and a blood pressure monitor for one or more patients,

a central patient safety monitor remote from the plurality of local patient safety monitors, the central patient safety monitor having a processor programmed for;

receiving data related to a plurality of physiological parameters from a patient over time;

generating a respective time series from the data from each of the plurality of physiological parameters;

identifying and organizing patterns and threshold violations along the plurality of time series into discrete objects forming object streams;

analyzing said discrete objects to identify known relational patterns;

converting said relational patterns into instances of relational binaries based on a physiological relationship between the discrete objects;

detecting a pattern of sepsis, the pattern being comprised of said relational binaries;

organizing and synthesizing said relational binaries into a set of failure images, which as an aggregate whole make up an image representation of the complex and dynamic state of sepsis; and

displaying the set of images as a motion image representation of the dynamic evolution of sepsis afflicting said patient on at least one of the central patient safety monitor or one of the plurality of local patient safety monitors upon the detection of said pattern of sepsis.

2. The system recited in claim 1, wherein both the identified patterns of the data and the relational patterns are converted into objects.

3. The system recited in claim 2, wherein the sepsis pattern comprises a cascade pattern of said objects spreading within a plurality of physiologic systems.

4. The system recited in claim 3, wherein the objects are color display objects and wherein the color of the display objects are responsive to severities of the corresponding identified patterns and relational patterns which are converted into the display objects so that the severities of individual perturbations and individual relational physiologic patterns are readily visible along the cascade pattern.

5. The system recited in claim 3, comprising determining a rate of growth of the cascade pattern responsive to a number and/or severity of new objects being added per unit time to the cascade pattern.

6. The system recited in claim 3, comprising determining a rate of growth of the cascade pattern responsive to the number of new physiologic systems being affected by the cascade per unit time.

7. The system recited in claim 1, comprising providing an automatic alarm at one of the plurality of local patient safety monitors upon the detection of said pattern of sepsis for a patient associated with said local patient safety monitor.

8. The system recited in claim 1, comprising generating a color motion image display of sepsis, the motion image display being dynamically responsive to a severity of the sepsis over time.

9. The system recited in claim 1, comprising generating a color motion image display of sepsis, the motion image display being dynamically responsive to a severity of the identified patterns over time.

10. The system recited in claim 1, comprising generating a color motion image display of sepsis, the motion image display being dynamically responsive to a severity of the relational patterns.

11. The system recited in claim 1, wherein the sepsis pattern comprises a cascade pattern of a plurality of said relational patterns, said relational patterns being derived from physiologic parameters from a progressively increasing number of physiologic systems over time.

12. The system recited in claim 11, wherein the healthcare system comprises an electronic medical record repository of data which comprises data from a plurality of patients and/or hospitals, and wherein the processor is programmed to identify the patient whose physiologic data is used to generate the cascade pattern and/or the hospital in which the patient whose physiologic data is used to generate a cascade pattern is located.

13. The system recited in claim 1, wherein the sepsis pattern comprises a cascade pattern of a plurality of said identified patterns of the data said identified patterns being derived from physiologic parameters from a progressively increasing number of physiologic systems over time.

14. The system recited in claim 13, comprising determining a plurality of states of evolution of the cascade pattern over time.

15. The system recited in claim 13, comprising determining a medical procedure preceding the cascade pattern wherein the cascade pattern comprises a potential complication of the medical procedure.

16. The system recited in claim 13, comprising determining a rate of growth of the cascade pattern responsive to a number and/or severity of new identified patterns being added to the cascade pattern over time.

17. The system recited in claim 13, comprising determining a rate of growth of the cascade pattern responsive to a number of new physiologic systems affected by the cascade pattern over time.

18. The system recited in claim 13, wherein the healthcare system comprises an electronic medical record repository of data which comprises data from a plurality of patients and/or hospitals, and wherein the processor is programmed to identify the patient whose physiologic data is used to generate the cascade pattern and/or the hospital in which said patient is located.

19. The system recited in claim 13, comprising, generating a color image display of sepsis, the color image display being responsive to a severity of the identified patterns along the cascade pattern.

20. The system recited in claim 13, comprising generating a plurality of time segments of the cascade pattern.

21. The system recited in claim 20, wherein the plurality of time segments of the cascade pattern comprises a set of sequential time segments of the cascade pattern.

22. The system recited in claim 21, wherein each new time segment of the set of sequential time segments has a longer duration than the time segment which preceded the new time segment.

23. The system recited in claim 22, wherein each new time segment of the set of sequential time segments contains the time segment which preceded the new time segment so that the cascade pattern grows in duration over time as each additional time segment is added to the set of sequential time segments.