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Reservoir device for intraocular drug delivery

  • US 10,470,924 B2
  • Filed: 10/11/2017
  • Issued: 11/12/2019
  • Est. Priority Date: 06/12/2001
  • Status: Expired due to Term
First Claim
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1. A sustained release delivery device, the delivery device comprising:

  • an elongate body having a proximal end and a distal end;

    an elastomeric wall disposed around at least a portion of the elongate body forming a reservoir having a reservoir volume;

    an inlet portion configured to be penetrated for injection of an amount of therapeutic agent into the reservoir after implantation in an eye; and

    at least one outlet from the reservoir,wherein the distal end of the elongate body is positioned away from the inlet and extends external to the reservoir,wherein the elastomeric wall is configured to adopt a collapsed configuration having a first cross-sectional dimension and an expanded configuration having a second cross-sectional dimension larger than the first cross-sectional dimension after injection of the amount of therapeutic agent into the reservoir, andwherein pressure of the elastomeric wall on the reservoir volume provides a driving force for delivery of the therapeutic agent from the reservoir through the at least one outlet into the vitreal cavity.

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