Devices, systems, and methods for the treatment of vascular defects

• US 10,478,195 B2
• Filed: 08/04/2016
• Issued: 11/19/2019
• Est. Priority Date: 08/04/2016
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Aboytes, Maria, Rosqueta, Arturo, Engelson, Erik, Wilson, Scott
• Primary Examiner(s): McEvoy, Thomas M
• Application Number:
  US15/228,278
• Publication Number:
  US 20180036012A1
• Time in Patent Office: 1,202 Days
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014

Abstract

Devices, systems, and methods for treating vascular defects are disclosed herein. One aspect of the present technology, for example, is directed toward an occlusion device that includes a proximal portion, a distal portion, and an intermediate portion extending between the proximal portion and the distal portion. The distal portion can include a directing region and a lead-in member that extends distally from the directing region. When the occlusion device is in a deployed configuration, the intermediate portion can form a preset bend in the occlusion device that positions the directing region at an angle with respect to the proximal portion. As a result, as the occlusion device is pushed distally out of a delivery catheter into the aneurysm, the directing region directs the distal portion away from exiting the aneurysm through the neck such that the proximal portion crosses the neck and generally remains within the aneurysm.

Claims

1. A vascular occlusion device for treating an aneurysm, wherein a neck of the aneurysm opens to a blood vessel, the device comprising:

a proximal portion having a mesh configured to be positioned within the aneurysm;

a distal portion including a directing region having;

a proximal terminus that coincides with a proximal terminus of the distal portion,

a distal terminus, wherein the directing region extends along a first direction that runs through the proximal terminus and the distal terminus, and

a length measured along the first longitudinal direction between the proximal terminus and the distal terminus; and

an intermediate mesh portion between the proximal and distal portions that, when in a deployed configuration, forms a preset bend in the device that orients the first longitudinal direction of the directing region at an angle to a portion of the proximal portion adjacent the intermediate mesh portion, wherein the angle is between about 45 degrees and about 135 degrees, and

wherein, when the device is being pushed distally out of a delivery catheter into the aneurysm, the directing region directs the distal portion to inhibit the distal portion from exiting the aneurysm through the neck such that the proximal portion crosses the neck and generally remains within the aneurysm,

wherein the device is configured to be implanted within the aneurysm.

2. The device of claim 1 wherein the directing region includes an elongated, generally cylindrical portion of the mesh.

3. The device of claim 1 wherein:

the intermediate mesh portion includes a portion of the mesh having a preset, curved shape; and

the directing region includes an elongated, generally cylindrical portion of the mesh.

4. The device of claim 1 wherein the directing region has a generally linear shape.

5. The device of claim 1 wherein the proximal portion has a second longitudinal direction immediately adjacent the intermediate mesh portion, and wherein the angle is between the first longitudinal direction of the directing region and the second longitudinal direction of the proximal portion.

6. The device of claim 1 wherein the mesh is a braid.

7. The device of claim 1 wherein the length of the directing region is from about 25% to about 75% of a diameter of the aneurysm.

8. The device of claim 1 wherein the length of the directing region is between about 0.05 inches and about 0.20 inches.

9. The device of claim 1 wherein the length of the directing region is between about 0.021 inches and about 0.20 inches.

10. The device of claim 1 wherein the length of the directing region is between about 0.021 inches and about 0.18 inches.

11. The device of claim 1 wherein the angle is between about 65 degrees and about 115 degrees.

12. The device of claim 1 wherein the angle is between about 70 degrees and about 110 degrees.

13. The device of claim 1 wherein the angle is between about 80 degrees and about 105 degrees.

14. A vascular occlusion device for treating an aneurysm, wherein a neck of the aneurysm opens to a blood vessel, the device comprising:

an expandable mesh having an elongated configuration and a deployed configuration, wherein, in the deployed configuration, the mesh includes;

a proximal portion formed of a flattened tubular braid configured to contact and conform to an inner surface of the aneurysm,

a radially compacted distal portion,

an intermediate mesh portion extending between the proximal portion and the distal portion, wherein the intermediate mesh portion is curved such that the distal portion is positioned at a predetermined angle with respect to the proximal portion; and

a directing region at the distal portion of the expandable mesh having a proximal terminus and a distal terminus, wherein the directing region extends along a first longitudinal direction that runs through the proximal terminus and the distal terminus, and wherein the directing region is positioned at an angle relative to the proximal portion between about 45 degrees and about 135 degrees, and

wherein, when the device is being pushed distally out of a delivery catheter into the aneurysm, the directing region directs the distal portion to inhibit the distal portion from exiting the aneurysm through the neck such that the proximal portion crosses the neck and generally remains within the aneurysm,

wherein the device is configured to be implanted within the aneurysm.

15. The device of claim 14 wherein the directing region includes an elongated, generally cylindrical portion of the mesh.

16. The device of claim 14 wherein the directing region has a generally linear shape.

17. The device of claim 14 wherein the proximal portion of the mesh forms a predetermined three-dimensional structure when the mesh is in a deployed configuration.

18. The device of claim 14 wherein the proximal portion of the mesh forms a plurality of curved, broad portions that together form a three-dimensional spherical structure when the mesh is in the deployed configuration.

19. The device of claim 14 wherein, when the mesh is in the deployed configuration, the proximal portion of the mesh forms (1) a first plurality of concave, broad portions that together form a first three-dimensional structure, and (2) a second plurality of concave, broad portions that together form a second three-dimensional structure that is configured to be deployed within an interior region defined by the first three-dimensional structure.