Probability based controller gain
First Claim
1. A method for estimating glucose level of a person having diabetes and selecting automatically open-loop and closed-loop control for a connected therapy delivery device, the method comprising:
- receiving into a blood glucose management device having a microcontroller a plurality of measured glucose results and corresponding impedance values from a glucose sensor coupled to the person;
using the microcontroller to analyze the plurality of measured glucose results and corresponding impedance values with a probability analysis tool configured to determine a total quality score Qtotal that is based on the minimum constraint of a set of quality metrics which comprises a probability of glucose sensor accuracy PA based on the plurality of measured glucose results and a probability of sensing quality Qac based on the impedance values;
using the microcontroller to estimate the glucose level of the person with a recursive filter configured to estimate the glucose level based on the plurality of measured glucose results weighted with the total quality score Qtotal; and
switching, via the microcontroller, the connected therapy delivery device automatically between open-loop control and closed-loop control based on the value of the total quality score Qtotal .
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Abstract
Methods and systems are disclosed for estimating a glucose level of a person having diabetes and selecting automatically open-loop and closed-loop control for a connected therapy delivery device. The method may comprise analyzing measured glucose results and corresponding impedance values received from a glucose sensor coupled to the person with a probability analysis tool implemented by a microcontroller to determine a total quality score that is based on the minimum constraint of a probability of glucose sensor accuracy determined measured glucose results and a probability of sensing quality determined from the impedance values. The microcontroller may estimate the glucose level of the person with a recursive filter based on the plurality of measured glucose results weighted with the total quality score and select automatically either open-loop control or closed-loop control for the connected therapy delivery device based on the value of the total quality score.
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Citations
44 Claims
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1. A method for estimating glucose level of a person having diabetes and selecting automatically open-loop and closed-loop control for a connected therapy delivery device, the method comprising:
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receiving into a blood glucose management device having a microcontroller a plurality of measured glucose results and corresponding impedance values from a glucose sensor coupled to the person; using the microcontroller to analyze the plurality of measured glucose results and corresponding impedance values with a probability analysis tool configured to determine a total quality score Qtotal that is based on the minimum constraint of a set of quality metrics which comprises a probability of glucose sensor accuracy PA based on the plurality of measured glucose results and a probability of sensing quality Qac based on the impedance values; using the microcontroller to estimate the glucose level of the person with a recursive filter configured to estimate the glucose level based on the plurality of measured glucose results weighted with the total quality score Qtotal; and
switching, via the microcontroller, the connected therapy delivery device automatically between open-loop control and closed-loop control based on the value of the total quality score Qtotal . - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 43)
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21. An apparatus for estimating a glucose level of a person having diabetes and selecting automatically open-loop and closed-loop control for a connected therapy delivery device, the apparatus comprising a microcontroller and a display, wherein:
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the microcontroller is configured to; receive a plurality of measured glucose results and corresponding impedance values from a glucose sensor coupled to the person, analyze the plurality of measured glucose results and corresponding impedance values with a probability analysis tool configured to determine a total quality score Qtotal that is based on the minimum constraint of a set of quality metrics which comprises a probability of glucose sensor accuracy PA based on the plurality of measured glucose results and a probability of sensing quality Qac based on the impedance values, estimate the glucose level of the person with a recursive filter configured to estimate the glucose level based on the plurality of measured glucose results weighted with the total quality score Qtotal, switch the connected therapy delivery device automatically between open-loop control and closed-loop control based on the value of the total quality score Qtotal, and transmit to the display information related to the estimate of the glucose level of the person and the control switch of the therapy delivery device. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 44)
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41. A method for estimating glucose level of a person having diabetes, the method comprising:
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collecting, via a blood glucose management device having a microcontroller, a plurality of measured glucose results and corresponding impedance values from a glucose sensor coupled to the person; using the microcontroller to analyze the plurality of measured glucose results and corresponding impedance values with a probability analysis tool configured to determine a total quality score Qtotal that is based on the minimum constraint of a set of quality metrics which comprises a probability of glucose sensor accuracy PA based on the plurality of measured glucose results and a probability of sensing quality Qac based on the impedance values; using the microcontroller to estimate the glucose level of the person with a recursive filter configured to estimate the glucose level based on the plurality of measured glucose results weighted with the total quality score Qtotal; and alerting via the microcontroller updating a display of the management device with a warning upon the estimated glucose level of the person being one of hypoglycemic and hyperglycemic.
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42. An apparatus for estimating a glucose level of a person having diabetes, the apparatus comprising a microcontroller and a display, wherein:
the microcontroller is configured to; collect a plurality of measured glucose results and corresponding impedance values from a glucose sensor coupled to the person, analyze the plurality of measured glucose results and corresponding impedance values with a probability analysis tool configured to determine a total quality score Qtotal that is based on the minimum constraint of a set of quality metrics which comprises a probability of glucose sensor accuracy PA based on the plurality of measured glucose results and a probability of sensing quality Qac based on the impedance values, estimate the glucose level of the person with a recursive filter configured to estimate the glucose level based on the plurality of measured glucose results weighted with the total quality score Qtotal, transmit to the display information related to the estimate of the glucose level of the person, and alert via the display with a warning upon the estimated glucose level of the person being one of hypoglycemic and hyperglycemic.
Specification