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Method to produce chemical pattern in micro-fluidic structure

  • US 10,486,153 B2
  • Filed: 05/23/2017
  • Issued: 11/26/2019
  • Est. Priority Date: 09/27/2013
  • Status: Active Grant
First Claim
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1. A method of forming a flow cell, the method comprising:

  • transferring an adhesive promoter onto one or both of a first substrate and a second substrate according to a pattern, wherein one or both of the first substrate and the second substrate are transparent;

    transferring a bio-medium onto the adhesive promoter to form a capture site pattern;

    forming a polymer layer on one or both of the first substrate and the second substrate; and

    polymer bonding the first substrate to the second substrate such that the polymer layer extends between a surface of the first substrate and a surface of the second substrate.

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