Devices, systems and methods for treating benign prostatic hyperplasia and other conditions

• US 10,492,792 B2
• Filed: 12/19/2016
• Issued: 12/03/2019
• Est. Priority Date: 05/20/2005
• Status: Active Grant

• Current Assignee: Teleflex Life Sciences III LLC
• Original Assignee: NeoTract, Inc. (Teleflex Incorporated)
• Inventors: Catanese, III, Joseph, Lamson, Theodore C., Makower, Joshua
• Primary Examiner(s): Anderson, Gregory A
• Application Number:
  US15/382,929
• Publication Number:
  US 20170100125A1
• Time in Patent Office: 1,079 Days
• CPC Class Codes: A61B 1/307 for the urinary organs, e.g. urethroscopes, cystoscopes
• CPC Class Codes: A61B 17/00234 for minimally invasive surgery A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/0218 for minimally invasive surgery A61B17/0281, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 17/0401 Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811
• CPC Class Codes: A61B 17/0467 Instruments for cutting sutures surgical cutting instruments A61B17/32
• CPC Class Codes: A61B 17/0469 Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
• CPC Class Codes: A61B 17/0482 Needle or suture guides guides for drills, pins or wire A61B17/17; for puncturing needles A61B17/3403
• CPC Class Codes: A61B 17/0487 Suture clamps, clips or locks, e.g. for replacing suture knots; Instruments for applying or removing suture clamps, clips or locks suture anchors A61B17/0401; wound clamps or clips A61B17/08; ligaturing clamps or clips A61B17/122
• CPC Class Codes: A61B 17/06109 Big needles, either gripped by hand or connectable to a handle
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 17/12 for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord specially adapted for vas deferens or fallopian tubes A61F6/20; materials for ligaturing blood vessels A61L17/00
• CPC Class Codes: A61B 17/12013 for use in minimally invasive surgery, e.g. endoscopic surgery
• CPC Class Codes: A61B 17/1227 Spring clips
• CPC Class Codes: A61B 17/32 Surgical cutting instruments A61B18/042 takes precedence; suture cutters A61B17/0467; instruments for ligaturing or cutting A61B17/128; instruments for rupturing the amniotic membrane A61B17/4208; specially adapted knives for eye surgery A61F9/0133
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61B 17/3478 Endoscopic needles, e.g. for infusion biopsy needles A61B10/0233; catheters with injection needles A61M25/0067
• CPC Class Codes: A61B 17/42 Gynaecological or obstetrical instruments or methods ligaturing clamps or clips for the umbilical cord A61B17/122; curettage A61B17/320708; dilators A61M29/00
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 18/20 : using laser
• CPC Class Codes: A61B 2017/00022 : Sensing or detecting at the treatment site
• CPC Class Codes: A61B 2017/00274 : Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2017/00792 : Plastic surgery
• CPC Class Codes: A61B 2017/00796 : Breast surgery
• CPC Class Codes: A61B 2017/00805 : Treatment of female stress urinary incontinence
• CPC Class Codes: A61B 2017/00862 : elastic or resilient
• CPC Class Codes: A61B 2017/00867 : shape memory effect
• CPC Class Codes: A61B 2017/00876 : magnetic
• CPC Class Codes: A61B 2017/00893 : pharmaceutically effective
• CPC Class Codes: A61B 2017/0404 : Buttons
• CPC Class Codes: A61B 2017/0409 : Instruments for applying suture anchors
• CPC Class Codes: A61B 2017/0417 : T-fasteners
• CPC Class Codes: A61B 2017/0419 : H-fasteners
• CPC Class Codes: A61B 2017/0451 : Cams or wedges holding the suture by friction
• CPC Class Codes: A61B 2017/0454 : the anchor being crimped or clamped on the suture
• CPC Class Codes: A61B 2017/0456 : Surface features on the anchor, e.g. ribs increasing friction between the suture and the anchor
• CPC Class Codes: A61B 2017/0458 : Longitudinal through hole, e.g. suture blocked by a distal suture knot
• CPC Class Codes: A61B 2017/0462 : One way system, i.e. also tensioning the suture
• CPC Class Codes: A61B 2017/0464 : for soft tissue
• CPC Class Codes: A61B 2017/0488 : Instruments for applying suture clamps, clips or locks
• CPC Class Codes: A61B 2017/06052 : Needle-suture combinations in which a suture is extending inside a hollow tubular needle, e.g. over the entire length of the needle
• CPC Class Codes: A61B 2017/06176 : with protrusions, e.g. barbs
• CPC Class Codes: A61B 2017/22061 : for spreading elements apart
• CPC Class Codes: A61B 2018/0022 : Balloons
• CPC Class Codes: A61B 2018/00547 : Prostate
• CPC Class Codes: A61B 2018/1407 : Loop
• CPC Class Codes: A61B 2018/1425 : Needle
• CPC Class Codes: A61B 2018/144 : Wire
• CPC Class Codes: A61B 2018/1475 : Electrodes retractable in or deployable from a housing
• CPC Class Codes: A61B 2090/3925 : ultrasonic
• CPC Class Codes: A61B 2090/3966 : Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61F 2002/041 : Bile ducts
• CPC Class Codes: A61M 5/158 : Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body

Abstract

Devices, systems and methods for compressing, cutting, incising, reconfiguring, remodeling, attaching, repositioning, supporting, dislocating or altering the composition of tissues or anatomical structures to alter their positional or force relationship to other tissues or anatomical structures. In some applications, the invention may be used to improve patency or fluid flow through a body lumen or cavity (e.g., to limit constriction of the urethra by an enlarged prostate gland).

Claims

1. A method for treating prostatic tissue with an implant delivery system, comprising:

accessing an interventional site adjacent prostatic tissue with the implant delivery system;

positioning the implant delivery system to deliver at least a portion of a retaining member within prostatic tissue;

delivering a substance capable of reducing blood flow to prostatic tissue, wherein the substance is a drug, biologic, or cell; and

maintaining compression of prostatic tissue with the retaining member after removal of the implant delivery system from the interventional site.

2. The method of claim 1 further comprising inducing atrophy in prostatic tissue.

3. The method of claim 1 further comprising inducing necrosis in prostatic tissue.

4. The method of claim 1 wherein compression is maintained for at least one month.

5. The method of claim 1 wherein the retaining member is bioabsorbable.

6. The method of claim 1 further comprising determining the extent of compression of prostatic tissue.

7. The method of claim 6 wherein the extent of compression of prostatic tissue is determined by visual inspection of displacement of the prostatic urethra.

8. The method of claim 1 wherein the substance is introduced into or near a prostate or adjacent tissue through a catheter.

9. The method of claim 1 wherein the substance is introduced into or near a prostate or adjacent tissue through a cannula needle.

10. The method of claim 1 wherein the substance is a hemostatic agent.

11. The method of claim 1 wherein the substance is a vasoconstricting agent.

12. The method of claim 1 wherein the substance is an antineoplastic agent.

13. The method of claim 1 wherein the substance creates a coagulative lesion.

14. The method of claim 1 wherein the substance causes the prostate to decrease in size.

15. The method of claim 1 wherein the substance is a vascularization inhibitor.

16. The method of claim 1 wherein the substance is an antitumor agent.

17. A method for treating prostatic tissue with an implant delivery system, comprising:

accessing an interventional site adjacent prostatic tissue with the implant delivery system;

positioning the implant delivery system to deliver at least a portion of a retaining member within prostatic tissue;

delivering a substance capable of reducing blood flow to prostatic tissue; and

maintaining compression of prostatic tissue with the retaining member after removal of the implant delivery system from the interventional site, wherein compression is maintained for at least three months.

18. The method of claim 17 wherein compression is maintained for at least six months.

19. The method of claim 17 wherein the retaining member is bioabsorbable.

20. The method of claim 17 wherein the substance is introduced into or near a prostate or adjacent tissue through a catheter.

21. The method of claim 17 wherein the substance is introduced into or near a prostate or adjacent tissue through a cannula needle.

22. The method of claim 17 wherein the substance is a hemostatic agent.

23. The method of claim 17 wherein the substance is a vasoconstricting agent.

24. The method of claim 17 wherein the substance is an antineoplastic agent.

25. The method of claim 17 wherein the substance creates a coagulative lesion.

26. The method of claim 17 wherein the substance causes the prostate to decrease in size.

27. The method of claim 17 wherein the substance is a vascularization inhibitor.

28. The method of claim 17 wherein the substance is an antitumor agent.