Device for soft tissue repair or replacement

• US 10,493,180 B2
• Filed: 06/09/2016
• Issued: 12/03/2019
• Est. Priority Date: 09/05/2008
• Status: Active Grant

• Current Assignee: Synovis Life Technologies Incorporated (Baxter International Inc.)
• Original Assignee: Synovis Life Technologies Incorporated (Baxter International Inc.)
• Inventors: Brunelle, John Eric, Weinstein, Al
• Primary Examiner(s): Scherbel, Todd J
• Application Number:
  US15/178,358
• Publication Number:
  US 20160325023A1
• Time in Patent Office: 1,272 Days
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable, resorptive for implantable prostheses A61F2210/0004
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61L 2300/414 Growth factors
• CPC Class Codes: A61L 2430/34 for soft tissue reconstruction
• CPC Class Codes: A61L 31/005 Ingredients of undetermined constitution or reaction products thereof
• CPC Class Codes: A61L 31/041 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 31/044 Collagen
• CPC Class Codes: A61L 31/145 Hydrogels or hydrocolloids
• CPC Class Codes: A61L 31/146 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

Disclosed are composite implantable tissue attachment devices comprising a mechanical reinforcing component and a cellular scaffold component. Disclosed devices include a wide, relatively flat portion for supporting long term repair of tissue. Disclosed devices can include a tapered portion at the end of the wide portions that can lead into a narrower elongated extension for aiding in placement of the device during a surgical procedure. The wide portion of the device can provide tensile strength along the longitudinal axis of the device as well as porosity. The wide devices can cover a larger surface area of a delivery site than standard suture. Disclosed materials can be utilized in, e.g., soft tissue repair such as tendon and ligament reconstruction and repair.

Claims

1. A composite implantable tissue attachment device, the device comprising:

a) a single-piece mechanical reinforcing component made of woven fibers comprising;

a central portion defining a length, a first width, and a depth, wherein the depth is less than the first width;

a first terminal portion; and

a single second terminal portion,

wherein the first terminal portion and the second terminal portion each define a second width, and wherein the second width is less than the first width, and

wherein the central portion defines a first porosity and each of the first terminal portion and second terminal portion define a second porosity that is less than the first porosity;

b) a first planar cellular scaffold component that overlays the central portion but not the first and second terminal portions of the mechanical reinforcing component; and

c) a second planar cellular scaffold component that overlays the central portion but not the first and second terminal portions of the mechanical reinforcing component;

wherein the first and second cellular scaffold components are discrete and layered directly upon opposite sides of the mechanical reinforcing component.

2. The composite implantable tissue attachment device according to claim 1, wherein the mechanical reinforcing component comprises multiple lengths of said central portion, wherein the multiple lengths are separated from one another by lengths of a neck.

3. The composite implantable tissue attachment device according to claim 1, wherein the first and second cellular scaffold components are collagen scaffolds.

4. The composite implantable tissue attachment device according to claim 3, wherein the collagen scaffolds comprise crosslinked collagen.

5. The composite implantable tissue attachment device according to claim 4, wherein the crosslinked collagen scaffolds are non-glutaraldehyde processed collagen scaffolds.

6. The composite implantable tissue attachment device according to claim 4, wherein the collagen scaffolds comprise crosslinked reconstituted collagen.

7. The composite implantable tissue attachment device according to claim 1, wherein the first and second cellular scaffold components comprise a hydrogel.

8. The composite implantable tissue attachment according to claim 1, wherein the fibers of the mechanical reinforcing component are polymeric fibers.

9. The composite implantable tissue attachment device according to claim 8, wherein the polymeric fibers comprise an absorbable polymer.

10. The composite implantable tissue attachment according to claim 1, the mechanical reinforcing component comprising a plurality of different fibers.

11. The composite implantable tissue attachment device according to claim 1, wherein the device is sterile.

12. The composite implantable tissue attachment device according to claim 1, wherein the first and second cellular scaffold components are shaped to match the shape of the central portion of the mechanical reinforcing component.

13. The composite implantable tissue attachment device according to claim 1, wherein the first and second cellular scaffold components are secured to a portion of a periphery of the mechanical reinforcing component.