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Tagged chimeric effector molecules and receptors thereof

  • US 10,494,434 B2
  • Filed: 12/22/2014
  • Issued: 12/03/2019
  • Est. Priority Date: 12/20/2013
  • Status: Active Grant
First Claim
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1. A single chain fusion protein, comprising an extracellular component and an intracellular component connected by a hydrophobic portion,wherein the extracellular component comprises a plurality of tag cassettes and a connector region comprising a hinge,wherein the intracellular component comprises an effector domain, andwherein at least one of the plurality of tag cassettes comprises a peptide having a length of up to 20 amino acids that includes the amino acid sequence of SEQ ID NO.:

  • 1 or 2.

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