Monitoring medication adherence

• US 10,496,796 B2
• Filed: 01/07/2016
• Issued: 12/03/2019
• Est. Priority Date: 12/23/2009
• Status: Active Grant

• Current Assignee: AI Cure Technologies LLC
• Original Assignee: AI Cure Technologies LLC
• Inventors: Hanina, Adam, Kessler, Gordon
• Primary Examiner(s): Ruhl, Dennis W
• Application Number:
  US14/990,226
• Publication Number:
  US 20160117483A1
• Time in Patent Office: 1,426 Days
• Field of Search: None
• CPC Class Codes: G06Q 10/10 Office automation; Time management
• CPC Class Codes: G16H 10/20 for electronic clinical trials or questionnaires
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 20/00 ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 20/60 relating to nutrition control, e.g. diets
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

A system and method of a clinical trial is provided. The system comprises a summary page providing an overview of each clinical trial participant in a graphical format, each clinical trial participant being represented by a unique clinical trial participant identifier and one or more clinical trial participant identifier modifiers applicable to modify one or more of the clinical trial participant identifiers, each modifier indicative of a different status of the particular participant identifier to which it is applied. A zoom selector is provided for zooming in on a subset of the clinical trial participant identifiers included with the summary page. Upon selection of a particular level of zoom, a corresponding amount of detailed information related to the subset of the clinical trial identifiers is provided; the detailed information including at least an indication of the level of compliance of a clinical trial participant to a prescribed clinical trial protocol represented by a corresponding clinical trial participant identifier, and further information related to any particular clinical trial participant identifier modifiers applied to any one of the clinical trial participant identifiers included within the subset.

Claims

1. A system for monitoring participant medication adherence in one or more clinical trials, the system comprising a computer configured to output to a display:

a graphical user interface comprising a summary page providing an overview of each clinical trial participant of a plurality of clinical trial participants in a graphical format, each clinical trial participant of the plurality of clinical trial participants being represented by a corresponding unique clinical trial participant identifier;

a plurality of clinical trial participant identifier modifiers applicable to modify a graphical representation of one or more of the clinical trial participant identifiers in the summary page, the plurality of modifiers including different types of modifiers, each different type of modifier being indicative of a different clinical trial participant status, wherein at least one modifier provides an indication of a deviation in compliance with a medical protocol by a clinical trial participant, an indication of a training status of the clinical trial participant, an indication of one or more usability errors, or an indication of a communication from the clinical trial participant; and

detailed information related to a subset of the clinical trial participant identifiers.

2. The system of claim 1, further comprising a computing device employing computer vision, wherein the computing device is operable to determine compliance with a medical protocol, by a clinical trial participant, by performing real-time automated video activity recognition operations comprising:

determining one or more procedures for administering a prescription regimen in accordance with a clinical trial;

identifying one or more video activity sequences associated with the one or more determined procedures;

capturing video activity sequences of the at least one clinical trial participant attempting to administer the prescription regimen;

storing the captured video activity sequences to a non-transitory computer readable storage medium; and

determining automatically in real time in accordance with the captured video activity sequences, whether the at least one clinical trial participant has properly administered the prescription regimen.

3. The system of claim 1, wherein the detailed information further includes one or more questions from at least one clinical trial participant.

4. The system of claim 1, wherein the detailed information further includes a status of review of instructions by at least one clinical trial participant represented by the corresponding clinical trial participant indicator.

5. The system of claim 1, wherein the detailed information further includes a status of medical supplies of at least one clinical trial participant represented by the corresponding clinical trial participant indicator.

6. The system of claim 1, wherein the detailed information further includes information about a medication prescribing physician associated with at least one clinical trial participant represented by the corresponding clinical trial participant indicator.

7. The system of claim 6, further comprising a communication system for communicating with the medication prescribing physician.

8. The system of claim 1, further comprising a communication system for communicating with one or more of the plurality of clinical trial participants.

9. A method for monitoring participant medication adherence in one or more clinical trials, comprising:

outputting from a computer to a display, a graphical user interface comprising a summary page depicting an overview of each clinical trial participant of a plurality of clinical trial participants in a graphical format, each clinical trial participant of the plurality of clinical trial participants being represented by a corresponding unique clinical trial participant identifier;

designating, on the display, one or more clinical trial participant identifier modifiers applicable to modify a graphical representation of one or more of the clinical trial participant identifiers in the summary view, the plurality of modifiers including different types of modifiers, each different type of modifier being indicative of a different clinical trial participant status, wherein at least one modifier provides an indication of a deviation in compliance with a medical protocol by a clinical trial participant, an indication of a training status of the clinical trial participant, an indication of one or more usability errors, or an indication of a communication from the clinical trial participant;

displaying, on the display detailed information related to a subset of clinical trial participant identifiers.

10. The method of claim 9, further comprising:

receiving a command to select a particular clinical trial participant identifier; and

responsive to receiving the command to select the particular clinical trial participant identifier, displaying, on the display, a more detailed set of information related to the selected clinical trial participant identifier.

11. The method of claim 10, comprising determining a deviation in compliance with a medical protocol by at least one clinical trial participant in accordance with real-time automated video activity sequence recognition, wherein determining the deviation comprises:

determining one or more procedures for administering a prescription regimen in accordance with a clinical trial;

identifying one or more video activity sequences associated with the one or more determined procedures;

capturing video activity sequences of the at least one clinical trial participant attempting to administer the prescription regimen;

storing the captured video activity sequences to a non-transitory computer readable storage medium; and

determining, automatically, in real time, in accordance with the captured video activity sequences, whether the at least one clinical trial participant has properly administered the prescription regimen.

12. The method of claim 9, further comprising broadcasting information related to one or more changes to a medication protocol to one or more of the plurality of clinical trial participants by selecting one or more of the clinical trial participant indicators from the summary screen on the display.

13. The method of claim 12, wherein the broadcasting information comprises video, audio or written instructions.

14. The method of claim 12, wherein the broadcasting information comprises a warning.

15. A system for monitoring medication adherence in one or more patients, the system comprising a computer configured to output to a display:

a graphical user interface comprising a summary page providing an overview of each of the one or more patients in a graphical format, each of the one or more patients being represented by a corresponding unique patent identifier;

a plurality of patient identifier modifiers applicable to modify a graphical representation of one or more of the patient identifiers in the summary view, the plurality of modifiers including different types of modifiers, each different type of modifier being indicative of a different patient status, wherein at least one modifier provides an indication of a deviation in compliance with a medical protocol by at least one patient, an indication of the training status of the at least one patient, an indication of one or more use errors, or an indication of a communication from the at least one patient; and

detailed information related to a subset of the patient identifiers.

16. The system of claim 15, wherein the computer comprises a processor operable to perform operations comprising:

determining one or more procedures for administering a prescription regimen;

identifying one or more video activity sequences associated with the one or more determined procedures;

capturing video activity sequences of at least one patient attempting to administer the prescription regimen;

storing the captured video activity sequences to a non-transitory computer readable storage medium; and

determining, automatically in real time, in accordance with the captured video activity sequences, whether the at least one patient has properly administered the prescription regimen.

17. The system of claim 15, wherein the detailed information includes one or more questions from at least one patient.

18. The system of claim 15, wherein the detailed information includes a status of review of instructions by at least one patient represented by the corresponding patient indicator.

19. The system of claim 15, wherein the detailed information includes a status of medical supplies of at least one patient represented by the corresponding patient indicator.

20. The system of claim 15, wherein the detailed information includes information about a medication prescribing physician associated with at least one patient represented by the corresponding patient indicator.