Scanning apparatus and methods useful for detection of chemical and biological analytes
First Claim
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1. A method of scanning a vessel, comprising(a) providing a detection apparatus that comprises(i) a vessel that comprises analytes;
- (ii) a detector(iii) a reference surface that forms a structural loop with the detector; and
(iv) a preload;
(b) examining a first subset of the analytes in the vessel while applying the preload to a first portion of the vessel but not a second portion of the vessel, wherein the preload facilitates contact between a first region of the vessel and the reference surface to position the first subset of analytes to occupy an area in an xy plane that is detected by the detector;
(c) translating the vessel along the reference surface; and
(d) examining a second subset of the analytes in the vessel while applying the preload to the second portion of the vessel but not the first portion of the vessel, wherein the preload facilitates contact between a second region of the vessel and the reference surface to position the second subset of the analytes to occupy the area in the xy plane that is detected by the detector.
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Abstract
An apparatus can include a vessel, a reference surface, a preload, a scan actuator, and a transmitter. The reference surface can form a structural loop with a detector. The preload can be configured to urge the vessel to contact an area on the reference surface. The scan actuator can be configured to slide the vessel along the reference surface in a scan dimension. The transmitter can be configured to direct signal from the vessel to a detector and/or direct energy from an energy source to the vessel, when the vessel is urged by the preload to contact the reference surface.
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Citations
20 Claims
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1. A method of scanning a vessel, comprising
(a) providing a detection apparatus that comprises (i) a vessel that comprises analytes; -
(ii) a detector (iii) a reference surface that forms a structural loop with the detector; and (iv) a preload; (b) examining a first subset of the analytes in the vessel while applying the preload to a first portion of the vessel but not a second portion of the vessel, wherein the preload facilitates contact between a first region of the vessel and the reference surface to position the first subset of analytes to occupy an area in an xy plane that is detected by the detector; (c) translating the vessel along the reference surface; and (d) examining a second subset of the analytes in the vessel while applying the preload to the second portion of the vessel but not the first portion of the vessel, wherein the preload facilitates contact between a second region of the vessel and the reference surface to position the second subset of the analytes to occupy the area in the xy plane that is detected by the detector. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification