Multiple fluid delivery system with multi-use disposable set and features thereof

• US 10,507,319 B2
• Filed: 01/07/2016
• Issued: 12/17/2019
• Est. Priority Date: 01/09/2015
• Status: Active Grant

• Current Assignee: Bayer Healthcare LLC (Bayer AG)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Haury, John A., Swantner, Michael, Sokolov, Richard, Cullen, Benjamin James, Norcott, Alison Ruth, Monis, Ernesto Hueso, Law, Kamman, Profaca, Mark Silvio, Spence, Patrick, Spohn, Michael A., Angert, Justin
• Primary Examiner(s): Stigell, Theodore J
• Application Number:
  US15/541,573
• Publication Number:
  US 20180015274A1
• Time in Patent Office: 1,440 Days
• CPC Class Codes: A61J 3/002 Compounding apparatus specially for enteral or parenteral nutritive solutions bottling liquids B67C
• CPC Class Codes: A61M 2205/07 having air pumping means
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 39/10 Tube connectors; Tube couplings A61M39/02 takes precedence; connecting needles to syringes or hubs A61M5/34; connecting catheter tubes to hubs A61M25/0014
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/1407 Infusion of two or more substances
• CPC Class Codes: A61M 5/14212 Pumping with an aspiration and an expulsion action
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/16881 Regulating valves on-off valves, e.g. clamps A61M39/28
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/3146 Priming, e.g. purging, reducing backlash or clearance

Abstract

A multi-use disposable set (MUDS) has at least one syringe having a proximal end and a distal end spaced apart from the proximal end along a longitudinal axis. The MUDS further has a plunger reciprocally movable within a syringe interior between the proximal end and the distal end. A manifold is in fluid communication with the distal end of the at least one syringe. At least one valve is in fluid communication with the syringe interior. The at least one valve is operable between a filling position for filling the syringe interior with fluid and a delivery position for delivering the fluid from the syringe interior. At least one connection port is in fluid communication with the manifold and the syringe interior when the at least one valve is in the delivery position. A multi-fluid delivery system having the medical convector and MUDS is also provided. Various features of the MUDS system are also described.

Claims

1. A multi-use disposable set (MUDS) comprising:

a plurality of syringes, each syringe having a proximal end and a distal end spaced apart from the proximal end along a longitudinal axis, a filling port and a discharge outlet at the distal end of each of the plurality of syringes, and a plunger reciprocally movable within a syringe interior of each of the plurality of syringes between the proximal end and the distal end;

a manifold in selectable fluid communication with the discharge outlet of each of the plurality of syringes;

at least one rotatable valve in fluid communication with the distal end of at least one of the plurality of syringes, wherein the at least one rotatable valve comprises a valve head with a slot recessed into the valve head, wherein the slot has a lip at one end of the slot which limits an orientation of a blade of a coupling mechanism of a fluid injector to a single self-aligned orientation, wherein the at least one rotatable valve is rotatably operable between a filling position for filling the syringe interior of the at least one of the plurality of syringes through the filling port and a delivery position for delivering fluid from the syringe interior of the at least one of the plurality of syringes to the manifold through the discharge outlet; and

at least one connection port in fluid communication with the manifold when the at least one rotatable valve is in the delivery position,

wherein the filling port is in fluid isolation from the syringe interior when the at least one rotatable valve is in the delivery position.

2. The MUDS of claim 1, wherein the at least one connection port is provided on a frame connected to at least one of the plurality of syringes.

3. The MUDS of claim 1, wherein the at least one connection port is in fluid communication with the manifold through a delivery line.

4. The MUDS of claim 1, further comprising a waste port in fluid connection with a waste reservoir.

5. The MUDS of claim 1, wherein each of the plurality of syringes further comprises a filling line with a spike configured for connection to a bulk fluid source, and wherein each filling line is configured for filling the syringe interior with a fluid from the bulk fluid source when the at least one rotatable valve is in the filling position.

6. The MUDS of claim 1, wherein the manifold has a fluid pathway in fluid communication with the discharge outlet of each of the plurality of syringes.

7. A multi-use disposable set (MUDS) comprising:

at least one syringe having a proximal end and a distal end spaced apart from the proximal end along a longitudinal axis, a filling port and a discharge outlet at the distal end of the at least one syringe, and a plunger reciprocally movable within an interior of the at least one syringe between the proximal end and the distal end;

a manifold in selectable fluid communication with the discharge outlet of each of the at least one syringe;

at least one rotatable valve in fluid communication with the interior of the at least one syringe, wherein the at least one rotatable valve comprises a valve head with a slot recessed into the valve head, wherein the slot has a lip at one end of the slot which limits an orientation of a blade of a coupling mechanism of a fluid injector to a single self-aligned orientation, wherein the at least one rotatable valve is rotatably operable between a filling position for filling the interior of the at least one syringe with fluid through the filling port and a delivery position for delivering the fluid from the interior of the at least one syringe to the manifold through the discharge port; and

at least one connection port in fluid communication with the manifold and the interior of the at least one syringe when the at least one rotatable valve is in the delivery position,

wherein the filling port is in fluid isolation from the interior of the at least one syringe when the at least one rotatable valve is in the delivery position.

8. The MUDS of claim 7, wherein the slot is shaped to receive the blade of the coupling mechanism for rotating the at least one rotatable valve between the filling position and the delivery position when the coupling mechanism engages the slot of the at least one rotatable valve.

9. The MUDS of claim 7, wherein the slot narrows in a direction from a distal end of the at least one rotatable valve to a proximal end of the at least one rotatable valve.

10. The MUDS of claim 7, wherein the at least one rotatable valve is rotatable between the filling position where the filling port is in fluid communication with the interior of the at least one syringe and the delivery position where the manifold is in fluid communication with the interior of the at least one syringe through the discharge outlet.

11. The MUDS of claim 7, wherein, in the filling position, the at least one rotatable valve is operable for filling the interior of the at least one syringe through the filling port in fluid communication with a bulk fluid source and in the delivery position, the at least one rotatable valve is operable for delivering fluid from the interior of the at least one syringe through the discharge outlet in fluid communication with the manifold.

12. The MUDS of claim 11, further comprising a filling line having a spike for connection to the bulk fluid source, wherein fluid flows from the bulk fluid source and the filling line into the interior of the at least one syringe through the filling port when the at least one rotatable valve is in the filling position.

13. The MUDS of claim 7, wherein the at least one connection port is provided on a frame connected to the at least one syringe.

14. The MUDS of claim 7, wherein the at least one connection port is in fluid communication with the manifold through a delivery line.

15. The MUDS of claim 7, wherein the at least one connection port has a waste port in fluid communication with a waste reservoir.

16. The MUDS of claim 7, wherein the manifold has a fluid pathway in fluid communication with the discharge outlet of the at least one syringe.

17. A multi-use disposable set (MUDS) comprising:

a plurality of syringes, each syringe having a proximal end and a distal end spaced apart from the proximal end along a longitudinal axis, a filling port and a discharge outlet at the distal end of each of the plurality of syringes, and a plunger reciprocally movable within a syringe interior of each of the plurality of syringes between the proximal end and the distal end;

a manifold connected to the discharge outlet of each of the plurality of syringes;

at least one rotatable valve associated with the manifold, the at least one rotatable valve rotatably operable between a filling position for filling the syringe interior of at least one of the plurality of syringes through the filling port and a delivery position for delivering fluid from the syringe interior of at least one of the plurality of syringes to the manifold through the discharge outlet;

at least one filling line in fluid communication with an interior of a bulk fluid source and the syringe interior of at least one of the plurality of syringes when the at least one rotatable valve is in the filling position; and

at least one connection port in fluid communication with the manifold and the syringe interior of at least one of the plurality of syringes when the at least one rotatable valve is in the delivery position,

wherein the at least one rotatable valve has a valve head with a slot recessed into the valve head,

wherein the slot is shaped to receive at least a portion of a coupling mechanism of a fluid injector for rotating the at least one rotatable valve between the filling position and the delivery position when the coupling mechanism engages the slot of the at least one rotatable valve wherein the slot has a lip at one end of the slot which limits an orientation of the portion of the coupling mechanism to a single self-aligned orientation; and

wherein the filling port is in fluid isolation from the syringe interior when the at least one rotatable valve is in the delivery position.

18. The MUDS of claim 17, wherein the manifold has a fluid pathway in fluid communication with the discharge outlet of each of the plurality of syringes.