Ocular tear film peak detection and stabilization detection systems and methods for determining tear film layer characteristics
First Claim
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1. An apparatus for peak detection of a tear film layer thickness(es) (TFLT), comprising:
- a control system configured to;
receive a plurality of images containing optical wave interference of specularly reflected light from a region of interest of an ocular tear film captured by an imaging device while illuminated by a multi-wavelength light source;
convert at least a portion of each image among the plurality of images representing the optical wave interference of specularly reflected light from at least a portion of the region of interest of the ocular tear film into at least one color-based value;
measure the TFLT of the at least a portion of the region of interest of the ocular tear film in each image among the plurality of images based on a comparison of the at least one color-based value to a tear film layer optical wave interference model;
determine a peak TFLT from a measured TFLT of the at least a portion of the region of interest of the ocular tear film among the plurality of images; and
generate a resulting image comprising the peak TFLT for the at least a portion of the region of interest of the ocular tear film.
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Abstract
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for peak detection and/or determining stabilization of an ocular tear film. Embodiments disclosed herein also include various image capturing and processing methods and related systems for providing various information about a patient'"'"'s ocular tear film (e.g., the lipid and aqueous layers) and a patient'"'"'s meibomian glands that can be used to analyze tear film layer thickness(es) (TFLT), and related characteristics as it relates to dry eye.
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Citations
14 Claims
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1. An apparatus for peak detection of a tear film layer thickness(es) (TFLT), comprising:
a control system configured to; receive a plurality of images containing optical wave interference of specularly reflected light from a region of interest of an ocular tear film captured by an imaging device while illuminated by a multi-wavelength light source; convert at least a portion of each image among the plurality of images representing the optical wave interference of specularly reflected light from at least a portion of the region of interest of the ocular tear film into at least one color-based value; measure the TFLT of the at least a portion of the region of interest of the ocular tear film in each image among the plurality of images based on a comparison of the at least one color-based value to a tear film layer optical wave interference model; determine a peak TFLT from a measured TFLT of the at least a portion of the region of interest of the ocular tear film among the plurality of images; and generate a resulting image comprising the peak TFLT for the at least a portion of the region of interest of the ocular tear film. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
Specification